Abstract: Alkylating agents such as the sulphur and nitrogen mustard gases react with the silver salts of dialkyl or diaryl substituted thiophosphoric acids at ambient temperature, thereby producing cholinesterase-inhibiting compounds. This new reaction is applied to a few prior art detection reactions and determination procedures of cholinesterase-inhibiting compounds.
Type:
Grant
Filed:
November 1, 1976
Date of Patent:
October 17, 1978
Assignee:
Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek ten behoeve van de Rijksverdediging
Inventors:
Anton Willem Barendsz, Cornelis De Borst, Alfred Johannes Antonius Post, Joannes Schimmel