Abstract: According to embodiments, a pulse band region is identified in a wavelet scalogram of a physiological signal (e.g., a plethysmograph or photoplethysmograph signal). Components of the scalogram at scales larger than the identified pulse band region are then used to determine a baseline signal in wavelet space. The baseline signal may then be used to normalize the physiological signal. Physiological information may be determined from the normalized signal. For example, oxygen saturation may be determined using a ratio of ratios or any other suitable technique.
Type:
Grant
Filed:
July 30, 2009
Date of Patent:
July 2, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
Braddon M. Van Slyke, Paul Stanley Addison, James Nicholas Watson, Scott McGonigle
Abstract: The present disclosure relates to systems and methods for analyzing and normalizing signals, such as PPG signals, for use in patent monitoring. The PPG signal may be detected using a continuous non-invasive blood pressure monitoring system and the normalized signals may be used to determine whether a recalibration of the system should be performed.
Type:
Grant
Filed:
September 30, 2009
Date of Patent:
June 11, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
James N. Watson, Rakesh Sethi, Robert Stoughton, Paul Stanley Addison
Abstract: A method and system are provided for evaluating in patient monitoring whether a signal is sensed optimally by receiving a signal, transforming the signal using a wavelet transform, generating a scalogram based at least in part on the transformed signal, identifying a pulse band in the scalogram, identifying a characteristic of the pulse band, determining, based on the characteristic of the pulse band, whether the signal is sensed optimally; and triggering an event. The characteristics of the pulse band and scalogram may be used to provide an indication of monitoring conditions.
Abstract: Systems and methods are provided for determining the pulse rate of a patient from multiple fiducial points using Gaussian kernel smoothing. Based on acquired pleth signals, each recorded fiducial pulse period is converted to a Gaussian kernel function. The Gaussian kernel functions for all recorded fiducial points are summed to generate a Gaussian kernel smoothed curve. The pulse rate of a patient may be determined from the Gaussian kernel smoothed curve. All acquired fiducial pulse periods contribute to generate the Gaussian kernel smoothing curve. The number of fiducial points utilized may change to improve pulse rate determination or provide additional functionality to the system.
Abstract: A patient monitoring system may generate an autocorrelation sequence for a physiological signal such as a photoplethysmograph signal. A series of peak values may be identified for the autocorrelation sequence. The peak values may be modified based on a historical distribution of a physiological parameter. A physiological parameter such as respiration rate may be determined based on the modified peak values.
Type:
Application
Filed:
November 30, 2011
Publication date:
May 30, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
Clark R. Baker, JR., James Ochs, James H. Dripps, Paul S. Addison
Abstract: According to embodiment, systems and methods for processing a physiological measurement and generating alarms based on the measurement are provided. Multiple features of a single physiological measurement may be concurrently monitored to generate alarms. One or more of the features may be based on a trend of the physiological measurement. One or more of the features may be based on a wavelet transform of the physiological measurement. Different features may be used in different combinations to lower the percentage of false alarms while still recognizing valid alarm events.
Abstract: According to embodiments, a respiration signal may be processed to normalize respiratory feature values in order to improve and/or simplify the interpretation and subsequent analysis of the signal. Data indicative of a signal may be received at a sensor and may be used to generate a respiration signal. Signal peaks in the respiration signal may be identified and signal peak thresholds may be determined. The identified signal peaks may be adjusted based on the signal peak threshold values to normalize the respiration signal.
Type:
Grant
Filed:
June 9, 2009
Date of Patent:
May 21, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
Scott McGonigle, Paul S. Addison, James N. Watson
Abstract: In some embodiments, systems and methods for identifying a low perfusion condition are provided by transforming a signal using a wavelet transform to generate a scalogram. A pulse band and adjacent marker regions in the scalogram are identified. Characteristics of the marker regions are used to detect the existence of a lower perfusion condition. If such a condition is detected, an event may be triggered, such as an alert or notification.
Type:
Grant
Filed:
August 23, 2011
Date of Patent:
April 30, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
James Nicholas Watson, Paul Stanley Addison, Edward M McKenna
Abstract: The present disclosure relates generally to patient monitoring systems and, more particularly, to signal analysis for patient monitoring systems. In one embodiment, a method of analyzing a detector signal of a physiological patient sensor includes obtaining the detector signal from the physiological patient sensor, wherein the detector signal crosses a horizontal boundary more than once. The method also includes determining the relative time and the slope of the detector signal at each boundary crossing. The method further includes estimating the amplitude of the detector signal based, at least in part, on the determined relative time and slope of the detector signal at each boundary crossing. The method also includes determining a physiological parameter of a patient based, at least in part, on the estimate of the amplitude of the detector signal.
Abstract: A patient monitoring system may determine one or more reference points of a physiological signal. The system may select one or more fiducial points on the physiological signal relative to the reference points. The one or more fiducial points may be selected by selecting a point spaced by a time interval relative to one of the reference points. The time interval may be a predetermined constant, or the time interval may depend on physiological information. The system may generate a fiducial signal based on the selected fiducial points, calculate physiological information such as a respiration rate based on the selected fiducial points, or both.
Abstract: A patient monitoring system may receive a photoplethysmograph (PPG) signal including samples of a pulse waveform. The PPG signal may demonstrate morphology changes based on respiration. The system may calculate morphology metrics from the PPG signal, the first derivative of the PPG signal, the second derivative of the PPG signal, or any combination thereof. The morphology metrics may demonstrate amplitude modulation, baseline modulation, and frequency modulation of the PPG signal that is related to respiration. Morphology metric signals generated from the morphology metrics may be used to determine respiration information such as respiration rate.
Type:
Application
Filed:
September 23, 2011
Publication date:
March 28, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
Scott McGonigle, Paul S. Addison, James Ochs, James Watson
Abstract: A signal representing physiological information may include information related to respiration. A patient monitoring system may utilize a wavelet transform to generate a scalogram from the signal. A threshold for the scalogram may be calculated, and scalogram values may be compared to the threshold. One of the scales meeting the threshold may be selected as representing respiration information such as respiration rate. The respiration information may be determined based on the selected scale.
Type:
Application
Filed:
September 23, 2011
Publication date:
March 28, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
James Ochs, James Watson, Binwel Weng, Paul S. Addison, Scott McGonigle
Abstract: A signal representing physiological information may include information related to respiration. A patient monitoring system may generate a plurality of autocorrelation sequences from the signal and combine the autocorrelation sequences to generate a combined autocorrelation sequence. The combined autocorrelation sequence may be analyzed to identify one or more peaks that may correspond to respiration information. Respiration information such as respiration rate may be determined based on the one or more peaks.
Type:
Application
Filed:
September 23, 2011
Publication date:
March 28, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
Jimmy Dripps, James Ochs, Paul S. Addison, James Watson
Abstract: A patient monitoring system may receive a photoplethysmograph (PPG) signal including samples of a pulse waveform. A plurality of morphology metric signals may be generated from the PPG signal. The system may generate an autocorrelation sequence for each of the morphology metric signals. An autocorrelation metric may be generated from each of the autocorrelation sequences and may represent the regularity or periodicity of the morphology metric signal. The autocorrelation sequences may be combined to generate a combined autocorrelation sequence, with the weighting of the autocorrelation sequences based on the autocorrelation metric. The combined autocorrelation sequence may be used to determine physiological information.
Type:
Application
Filed:
September 23, 2011
Publication date:
March 28, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
James Ochs, Paul S. Addison, James Watson
Abstract: A method and system for automatically gating an imaging device is disclosed. Physiological process information of a patient may be derived from a plethysmographic signal, for example, by analyzing the plethysmographic signal transformed by a continuous wavelet transform. Other techniques for deriving physiological process information of a patient include, for example, analyzing a scalogram derived from the continuous wavelet transform. The physiological process information may be used to automatically gate imaging data acquired from an imaging device in order to synchronize the imaging data with the physiological process information.
Type:
Grant
Filed:
September 25, 2009
Date of Patent:
March 19, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
Robert Stoughton, Paul S. Addison, James N. Watson
Abstract: Methods and systems are discussed for determining venous oxygen saturation by calculating a ratio of ratios from respiration-induced baseline modulations. A calculated venous ratio of ratios may be compared with a look-up table value to estimate venous oxygen saturation. A calculated venous ratio of ratios is compared with an arterial ratio of ratios to determine whether baseline modulations are the result of a subject's respiration or movement. Such a determination is also made by deriving a venous ratio of ratios using a transform technique, such as a continuous wavelet transform. Derived venous and arterial saturation values are used to non-invasively determine a cardiac output of the subject.
Type:
Application
Filed:
September 9, 2011
Publication date:
March 14, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
Paul Addison, James Watson, Paul Mannheimer
Abstract: Methods and systems are discussed for determining venous oxygen saturation by calculating a ratio of ratios from respiration-induced baseline modulations. A calculated venous ratio of ratios may be compared with a look-up table value to estimate venous oxygen saturation. A calculated venous ratio of ratios is compared with an arterial ratio of ratios to determine whether baseline modulations are the result of a subject's respiration or movement. Such a determination is also made by deriving a venous ratio of ratios using a transform technique, such as a continuous wavelet transform. Derived venous and arterial saturation values are used to non-invasively determine a cardiac output of the subject.
Abstract: Methods and systems are discussed for determining venous oxygen saturation by calculating a ratio of ratios from respiration-induced baseline modulations. A calculated venous ratio of ratios may be compared with a look-up table value to estimate venous oxygen saturation. A calculated venous ratio of ratios is compared with an arterial ratio of ratios to determine whether baseline modulations are the result of a subject's respiration or movement. Such a determination is also made by deriving a venous ratio of ratios using a transform technique, such as a continuous wavelet transform. Derived venous and arterial saturation values are used to non-invasively determine a cardiac output of the subject.
Type:
Application
Filed:
September 9, 2011
Publication date:
March 14, 2013
Applicant:
Nellcor Puritan Bennett Ireland
Inventors:
Paul S. Addison, James Watson, James Ochs, Scott McGonigle
Abstract: Methods and systems are discussed for determining venous oxygen saturation by calculating a ratio of ratios from respiration-induced baseline modulations. A calculated venous ratio of ratios may be compared with a look-up table value to estimate venous oxygen saturation. A calculated venous ratio of ratios is compared with an arterial ratio of ratios to determine whether baseline modulations are the result of a subject's respiration or movement. Such a determination is also made by deriving a venous ratio of ratios using a transform technique, such as a continuous wavelet transform. Derived venous and arterial saturation values are used to non-invasively determine a cardiac output of the subject.
Abstract: According to embodiments, systems and methods for reducing noise in a signal are provided. A signal may be transformed using a continuous wavelet transform and a corresponding scalogram may be generated. Regions of noise may be identified from the resulting scalogram. These regions may be masked by, for example, removing, altering, or appropriately tagging the regions. After masking the regions of noise, the scalogram may be converted to a filtered signal using an inverse wavelet transform. Alternatively or additionally, desirable regions of non-noise may instead be identified from the resulting scalogram. These desirable regions may be extracted from the scalogram and an inverse wavelet transform performed on the extracted regions in order to generate a filtered signal.
Type:
Grant
Filed:
October 10, 2008
Date of Patent:
February 26, 2013
Assignee:
Nellcor Puritan Bennett Ireland
Inventors:
James Nicholas Watson, Paul Stanley Addison