Patents Assigned to Nellix, Inc.
  • Patent number: 10022249
    Abstract: Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: July 17, 2018
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
  • Patent number: 9814612
    Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: November 14, 2017
    Assignee: Nellix, Inc.
    Inventors: Charles S. Taylor, Christopher Zarins, Robert A. Geshlider, Dwight P. Morejohn, Peter Johansson, Susan W. Vican, James T. McKinley
  • Patent number: 9737425
    Abstract: Methods and systems for treating aneurysms using filling structures filled with a curable medium are described herein. Such methods can include positioning a double-walled filling structure across the aneurysm and filling with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device during and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: August 22, 2017
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Wantanabe, Amy Lee, Steven L. Herbowy
  • Patent number: 9730700
    Abstract: A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: August 15, 2017
    Assignee: Nellix, Inc.
    Inventors: Steven L. Herbowy, Michael A. Evans, Anant Kumar, K. T. Venkateswara Rao, Matthew R. Hellewell, Gil Laroya
  • Publication number: 20160030215
    Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.
    Type: Application
    Filed: October 21, 2015
    Publication date: February 4, 2016
    Applicant: NELLIX, INC.
    Inventors: CHARLES S. TAYLOR, CHRISTOPHER ZARINS, ROBERT A. GESHLIDER, DWIGHT P. MOREJOHN, PETER JOHANSSON, SUSAN W. VICAN, JAMES T. MCKINLEY
  • Patent number: 9113999
    Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: August 25, 2015
    Assignee: Nellix, Inc.
    Inventors: Charles S. Taylor, Christopher Zarins, Robert A. Geshlider, Dwight P. Morejohn, Peter Johansson, Susan W. Vican, James T. McKinley
  • Patent number: 8945199
    Abstract: A system for treating an aneurysm comprises at least a first double-walled filling structure having an outer wall and an inner wall and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to the inside surface of the aneurysm and the inner surface forms a generally tubular lumen to provide blood flow. The first filling structure comprises a sealing feature which forms a fluid seal between the filling structure and the aneurysm or an adjacent endograft when the filling structure is filled with the hardenable fluid filling medium, thereby minimizing or preventing blood flow downstream of the seal.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: February 3, 2015
    Assignee: Nellix, Inc.
    Inventors: Raj P. Ganpath, Amy Lee, Craig Rosenberg, Sherwin Llamido, Steven L. Herbowy, Michael A. Evans, Thomas A. Howell, Charles S. Taylor, K. T. Venkateswara Rao
  • Patent number: 8926682
    Abstract: A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: January 6, 2015
    Assignee: Nellix, Inc.
    Inventors: Steven L. Herbowy, Michael A. Evans, Anant Kumar, K. T. Venkateswara Rao, Matthew R. Hellewell, Gil Laroya
  • Patent number: 8906084
    Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: December 9, 2014
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
  • Publication number: 20110276078
    Abstract: A system for treating an aneurysm includes a first double-walled filling structure having an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a generally tubular lumen to permit blood flow therethrough. The inner wall comprises a blood contacting layer and a reinforcing layer. The reinforcing layer prevents circumferential creep or elastic expansion of the lumen.
    Type: Application
    Filed: December 13, 2010
    Publication date: November 10, 2011
    Applicant: Nellix, Inc.
    Inventors: K.T. Venkateswara Rao, Raj P. Ganpath, Amy Lee, Anupama Karwa
  • Publication number: 20110208042
    Abstract: The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
    Type: Application
    Filed: May 4, 2011
    Publication date: August 25, 2011
    Applicant: Nellix, Inc.
    Inventors: Amy Lee, Michael A. Evans
  • Patent number: 7951448
    Abstract: The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: May 31, 2011
    Assignee: Nellix, Inc.
    Inventors: Amy Lee, Michael A. Evans
  • Publication number: 20100312267
    Abstract: The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
    Type: Application
    Filed: August 17, 2010
    Publication date: December 9, 2010
    Applicant: Nellix, Inc.
    Inventors: Amy Lee, Michael A. Evans
  • Patent number: 7790273
    Abstract: The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: September 7, 2010
    Assignee: Nellix, Inc.
    Inventors: Amy Lee, Michael A. Evans
  • Publication number: 20100106087
    Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
    Type: Application
    Filed: January 7, 2010
    Publication date: April 29, 2010
    Applicant: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
  • Patent number: 7666220
    Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: February 23, 2010
    Assignee: Nellix, Inc.
    Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
  • Publication number: 20100036360
    Abstract: A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.
    Type: Application
    Filed: April 24, 2009
    Publication date: February 11, 2010
    Applicant: Nellix, Inc.
    Inventors: Steven L. Herbowy, Michael A. Evans, Anant Kumar, K.T. Venkateswara Rao, Matthew R. Hellewell, Gil Laroya
  • Publication number: 20100004728
    Abstract: A prosthesis comprises a tubular body that is expandable from a contracted configuration to a radially expanded configuration. The tubular body has a total length and comprises a first section, a second section and a central section disposed therebetween. The total length of the tubular body in the expanded configuration is at least 95% of the total length of the tubular body in the contracted configuration. The three sections have a plurality of tubular rings, each with a plurality of struts having a length and coupled together to form a series of peaks and valleys. A connector couples adjacent tubular rings together. The length of the central section struts is different than the length of the other struts and the central section is coupled with both the first and second sections.
    Type: Application
    Filed: February 13, 2009
    Publication date: January 7, 2010
    Applicant: Nellix, Inc.
    Inventors: K.T. Venkateswara Rao, Anant Kumar, Ivan Tzvetanov
  • Publication number: 20090318949
    Abstract: A system for treating an aneurysm comprises at least a first double-walled filling structure having an outer wall and an inner wall and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to the inside surface of the aneurysm and the inner surface forms a generally tubular lumen to provide blood flow. The first filling structure comprises a sealing feature which forms a fluid seal between the filling structure and the aneurysm or an adjacent endograft when the filling structure is filled with the hardenable fluid filling medium, thereby minimizing or preventing blood flow downstream of the seal.
    Type: Application
    Filed: June 4, 2009
    Publication date: December 24, 2009
    Applicant: Nellix, Inc.
    Inventors: Raj P. Ganpath, Amy Lee, Craig Rosenberg, Sherwin Llamido, Steven L. Herbowy, Michael A. Evans, Thomas A. Howell, Charles S. Taylor, K.T. Venkateswara Rao
  • Publication number: 20090319029
    Abstract: A system for treating an aneurysm in a blood vessel comprises a docking scaffold having with upstream and downstream ends, and a central passageway therebetween. The upstream end engages the blood vessel upstream of the aneurysm. A portion of a first and second scaffolds are slidably received in the central passageway such that an outside surface of the first and second scaffolds engage an inside surface of the docking scaffold. A double-walled filling structure has outer and inner walls and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow therethrough. The double-walled filling structure is coupled with at least one of the first and second leg scaffolds in expanded configuration.
    Type: Application
    Filed: June 4, 2009
    Publication date: December 24, 2009
    Applicant: Nellix, Inc.
    Inventors: Michael A. Evans, Ivan Tzvetanov, Steven L. Herbowy, Raj P. Ganpath, Amy Lee, Anant Kumar, Gwendolyn A. Watanabe, K.T. Venkateswara Rao