Patents Assigned to NEOMORPH, INC.
  • PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE
    Publication number: 20240034723
    Abstract: Disclosed are compounds and pharmaceutically acceptable salts, hydrates, solvates, prodrugs, stereoisomers, or tautomers thereof that may cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders associated with Helios and which may benefit from Helios degradation.
    Type: Application
    Filed: October 15, 2021
    Publication date: February 1, 2024
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., NEOMORPH, INC.
    Inventors: Hu Liu, Tinghu Zhang, Lyn Jones, Jianwei Che, Brian Bear, Whitney Petrilli