Abstract: The disclosure provides reagents, methods, and kits, for treating melanoma. The reagent encompasses interferon-gamma (IFN-gamma) responsive melanoma cells, where the cells are autophagic and non-apoptotic melanoma cells, and where the cells express MHC Class II. In another aspect, the reagent encompassed dendritic cells loaded with the IFN-gamma responsive, non-apoptotic, MHC Class II-expressing melanoma cells.
Abstract: The disclosure provides cancer stem cells, for use in stimulating immune response against a cancer, such as ovarian carcinoma. Methods for preparing and purifying the cancer stem cells are provided.
Abstract: The present disclosure provides reagents and methods for stimulating an immune response against an antigen associated with glioblastoma multiforme.
Type:
Application
Filed:
March 12, 2014
Publication date:
February 4, 2016
Applicant:
NEOSTEM ONCOLOGY, LLC
Inventors:
Candace Y. Hsieh, Andrew N. Cornforth, Gabriel Nistor
Abstract: The disclosure provides cancer stem cells, for use in stimulating immune response against a cancer, such as colon carcinoma (CC). Methods for preparing and purifying the cancer stem cells are provided.
Type:
Application
Filed:
March 12, 2014
Publication date:
January 28, 2016
Applicant:
NEOSTEM ONCOLOGY, LLC
Inventors:
Candace Y. Hsieh, Andrew N. Cornforth, Gabriel Nistor
Abstract: The disclosure provides cancer stem cells, for use in stimulating immune response against a cancer, such as hepatocellular carcinoma (HCC). Methods for preparing and purifying the cancer stem cells are provided.
Type:
Application
Filed:
March 6, 2014
Publication date:
January 21, 2016
Applicant:
NEOSTEM ONCOLOGY, LLC
Inventors:
Gabriel Nistor, Craig T. Frederickson, Andrew N. Cornforth