Abstract: Compounds represented by the following structure (II) are disclosed: as are methods for making such compounds. Compositions and methods for treating various disease conditions including cancer and non-cancer diseases associated with vascular proliferation are also disclosed.
Type:
Grant
Filed:
November 2, 2007
Date of Patent:
March 6, 2012
Assignee:
Nereus Pharmacuticals, Inc.
Inventors:
Michael A. Palladino, George Kenneth Lloyd, Yoshio Hayashi