Abstract: This invention is directed to a method to reduce microbial fouling on a surface. The present invention provides antifouling coatings similar to the protein glues secreted by marine mussels for adhesion to underwater substrates.

Abstract: Synthesis methods for creating polymeric compounds comprising dihydroxyphenyl derivatives (DHPD), or DHPp i.e. polymers modified with DHPD, with desired surface active effects are described. The polymer backbone of DHPp has structural or performance features that can be tailored to control physical properties of DHPp, allowing it to be useful for different applications i.e. tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.

Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.

Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.

Abstract: Embodiments of a delivery device, a kit comprising the delivery device, and methods of using the same are presented. In one embodiment, the delivery device includes a syringe assembly defining two or more reservoirs each configured to hold a dispensable material. Additionally, the delivery device may include a delivery tip. The delivery tip may have an inlet, an outlet, a central flow-restricting portion, and one or more channels adjacent to the central flow-restricting portion that provide fluid communication between the inlet and the outlet, the one or more channels including a section that tapers inwardly toward the outlet. In one embodiment, the delivery device is configured such that if the two or more reservoirs hold dispensable material then the syringe assembly can be actuated to dispense the dispensable material from the two or more reservoirs substantially simultaneously into the inlet.

Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.

Abstract: Synthesis methods for creating polymeric compounds comprising dihydroxyphenyl derivatives (DHPD), or DHPp i.e. polymers modified with DHPD, with desired surface active effects are described. The polymer backbone of DHPp has structural or performance features that can be tailored to control physical properties of DHPp, allowing it to be useful for different applications i.e. tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.

Abstract: The invention describes DOPA functionalized, branched, polyalkylene oxide materials that are useful as adhesives.