Patent number: 6180649
Abstract: The present invention discloses compounds of the formula
wherein the dotted bonds are optional extra bonds allowing any tautomeric isomers compatible with substituents X and R3;
R3 is non-existing, hydrogen, or alkyl;
X is O, S, imino, alkoxy, alkylthio, or amino;
R1 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, acyl, acylalkyl, alkoxyalkyl, dialkoxyalkyl, or phenylalkyl which may be substituted with alkyl, halogen, amino, nitro or cyano; and
R4, R5, R6 and R7 independently of each other are hydrogen; halogen; amino; nitro;
CN; CF3; COOH; COO-alkyl; alkyl; acyl; alkoxy; —(CH2)n,—OH wherein n is 0, 1, 2, or 3; —(CH2)m—O-alkyl wherein m is 0, 1,2, or 3; —(CH2)p—O-acyl wherein p is 0, 1,2, or 3;
or a pharmaceutically acceptable addition salt thereof.
Type:
Grant
Filed:
November 19, 1998
Date of Patent:
January 30, 2001
Assignee:
NeroSearch A/S
Inventors:
Peter Moldt, Bjarne Hugo Dahl, Jorgen Drejer, Oskar Axelsson