Patents Assigned to NerPharMa S.r.l.
  • Safe and efficient process for the preparation of carmustine
    Patent number: 10519104
    Abstract: Carmustine may be safely and efficiently produced by reacting 2-chloroethylamine hydrochloride and 1,1?-carbonyldiimidazole to afford 1,3-bis(2-chloroethyl)-1-urea, followed by nitrosation to give the final product.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: December 31, 2019
    Assignee: NerPharMa S.r.l.
    Inventors: Attilio Tomasi, Ilaria Candiani, Francesco Corcella, Francesco Saverio Caldarelli
  • SAFE AND EFFICIENT PROCESS FOR THE PREPARATION OF CARMUSTINE
    Publication number: 20170253557
    Abstract: Carmustine may be safely and efficiently produced by reacting 2-chloroethylamine hydrochloride and 1,1?-carbonyldiimidazole to afford 1,3-bis(2-chloroethyl)-1-urea, followed by nitrosation to give the final product.
    Type: Application
    Filed: February 28, 2017
    Publication date: September 7, 2017
    Applicant: NerPharMa S.r.l.
    Inventors: Attilio TOMASI, Ilaria Candiani, Francesco Corcella, Francesco Saverio Caldarelli