Patents Assigned to Neuralab Limited
  • Patent number: 6913745
    Abstract: Disclosed are pharmaceutical compositions and methods for preventing or treating a number of amyloid diseases, including Alzheimer's disease, prion diseases, familial amyloid neuropathies and the like. The pharmaceutical compositions include immunologically reactive amounts of amyloid fibril components, particularly fibril-forming peptides or proteins. Also disclosed are therapeutic compositions and methods which use immune reagents that react with such fibril components.
    Type: Grant
    Filed: June 1, 2000
    Date of Patent: July 5, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Publication number: 20050142132
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A? and antibodies binding to the same.
    Type: Application
    Filed: February 14, 2005
    Publication date: June 30, 2005
    Applicant: Neuralab Limited
    Inventors: Dale Schenk, Frederique Bard, Theodore Yednock
  • Patent number: 6905686
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A? and antibodies binding to the same.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: June 14, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Publication number: 20050123544
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A? and antibodies binding to the same.
    Type: Application
    Filed: November 24, 2004
    Publication date: June 9, 2005
    Applicant: Neuralab Limited
    Inventors: Dale Schenk, Frederique Bard, Theodore Yednock
  • Publication number: 20050118651
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Preferred agents include antibodies, e.g., humanized antibodies.
    Type: Application
    Filed: June 1, 2004
    Publication date: June 2, 2005
    Applicants: Neuralab Limited, Wyeth
    Inventors: Guriq Basi, Jose Saldanha, Frederique Bard
  • Patent number: 6890535
    Abstract: Disclosed are pharmaceutical compositions and methods for preventing or treating a number of amyloid diseases, including Alzheimer's disesase, prion diseases, familial amyloid neuropathies and the like. The pharmaceutical compositions include immunologically reactive amounts of amyloid fibril components, particularly fibril-forming peptides or proteins. Also disclosed are therapeutic compositions and methods which use immune reagents that react with such fibril components.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 10, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Patent number: 6875434
    Abstract: Disclosed are pharmaceutical compositions and methods for preventing or treating a number of amyloid diseases, including Alzheimer's disesase, prion diseases, familial amyloid neuropathies and the like. The pharmaceutical compositions include immunologically reactive amounts of amyloid fibril components, particularly fibril-forming peptides or proteins. Also disclosed are therapeutic compositions and methods which use immune reagents that react with such fibril components.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: April 5, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Publication number: 20050059591
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A? and antibodies binding to the same.
    Type: Application
    Filed: April 12, 2004
    Publication date: March 17, 2005
    Applicant: Neuralab Limited
    Inventors: Dale Schenk, Nicki Vasquez, Theodore Yednock
  • Patent number: 6866850
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: March 15, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Patent number: 6866849
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: March 15, 2005
    Assignee: Neuralab Limited
    Inventor: Dale B. Schenk
  • Publication number: 20050053614
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Application
    Filed: July 1, 2004
    Publication date: March 10, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050048049
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide, active fragments thereof or an antibody thereto.
    Type: Application
    Filed: August 20, 2004
    Publication date: March 3, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050037026
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Application
    Filed: September 2, 2004
    Publication date: February 17, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050031629
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Application
    Filed: March 31, 2004
    Publication date: February 10, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050019343
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide or an antibody thereto.
    Type: Application
    Filed: September 2, 2004
    Publication date: January 27, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050019330
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide, active fragments thereof or an antibody thereto.
    Type: Application
    Filed: August 20, 2004
    Publication date: January 27, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050019328
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A? in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A? and antibodies binding to the same.
    Type: Application
    Filed: April 12, 2004
    Publication date: January 27, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20050013815
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A? peptide, active fragments thereof or an antibody thereto.
    Type: Application
    Filed: August 20, 2004
    Publication date: January 20, 2005
    Applicant: Neuralab Limited
    Inventor: Dale Schenk
  • Publication number: 20040265308
    Abstract: The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A&bgr; peptide, active fragments thereof or an antibody thereto.
    Type: Application
    Filed: February 27, 2004
    Publication date: December 30, 2004
    Applicant: Neuralab Limited
    Inventor: Dale B. Schenk
  • Publication number: 20040265301
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A&bgr; in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A&bgr; and antibodies binding to the same.
    Type: Application
    Filed: July 12, 2004
    Publication date: December 30, 2004
    Applicant: Neuralab Limited
    Inventors: Dale B. Schenk, Frederique Bard, Theodore Yednock