Abstract: The invention concerns the use of PDE2 inhibitors for treating disorders of the central and peripheral nervous system, a method for therapeutic treatment by administering to an animal said inhibitors. More specifically, the invention concerns novel benzodiazepinone derivatives and their uses in therapeutics more particularly for treating pathologies involving activity of a cyclic nucleotide phosphodiesterase type 2. The invention also concerns methods for preparing same and novel synthesis intermediates.
Type:
Application
Filed:
October 30, 2003
Publication date:
June 15, 2006
Applicants:
NEURO3D, UNIVERSITE LOUIS PASTEUR
Inventors:
Jean-Jacques Bourguignon, Claire Lugnier, Mustapha Abarghaz, Yan Lagouge, Patrick Wagner, Cesare Mondadori, Jean-Paul Macher, Dominique Schultz, Pierre Raboisson