Abstract: The present invention relates to a pharmaceutical composition comprising (S)-2-(((4?-trifluoromethylbiphenyl-4-yl)methyl)amino)propanamide methanesulfonate or a pharmaceutically acceptable salt thereof as an effective ingredient for prevention or treatment of stroke.
Type:
Application
Filed:
April 1, 2019
Publication date:
December 30, 2021
Applicant:
NEUROBIOGEN CO.,LTD
Inventors:
Ki Duk PARK, Changjoon LEE, Soo-Jin OH, Ae Nim PAE, Sang Min LIM, Jong Hyun PARK, Min-Ho NAM, Hyoung Ihl KIM, Ji Young PARK, Jongwook CHO
Abstract: The present disclosure relates to an ?-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.
Type:
Grant
Filed:
April 24, 2020
Date of Patent:
July 6, 2021
Assignee:
NeuroBiogen Co., Ltd.
Inventors:
Ki Duk Park, ChangJoon Justin Lee, Dong Jin Kim, Ae Nim Pae, Hyun Ah Choo, Sun Joon Min, Yong Koo Kang, Yun Kyung Kim, Hyo Jung Song, Ji Won Choi, Min Ho Nam, Jun Young Heo, Seul Ki Yeon, Bo Ko Jang, Eun Ji Ju, Seon Mi Jo, Jong-Hyun Park
Abstract: The present invention relates to a pharmaceutical composition comprising (S)-2-(((4?-trifluoromethylbiphenyl-4-yl)methyl)amino)propanamide methanesulfonate or a pharmaceutically acceptable salt thereof as an effective ingredient for prevention or treatment of spinal cord injury.
Type:
Application
Filed:
February 7, 2019
Publication date:
February 4, 2021
Applicant:
NEUROBIOGEN CO.,LTD
Inventors:
Ki Duk PARK, Changjoon LEE, Ae Nim PAE, Soo-Jin OH, Sang Min LIM, Jong Hyun PARK, Jungmoo LEE, Yoon HA, Hye Yeong LEE