Abstract: A composition for improving sleep. In one embodiment, the composition comprises L-Tryptophan, L-Theanine, Reishi mushroom extract, Uridine, a polyphenol, and paeoniflorin. In certain embodiments, the composition further comprises citrus bioflavonoid extract, ?-Oryzanol, holy basil extract, saffron extract, Schisandra chinensis extract, sesamin extract, blueberry extract, quercetin, Polygala tenuifolia root extract, gotu kola extract, ashwagandha extract, betaine, magnesium, or combinations thereof. In other embodiments, the composition further comprises astaxanthin, lycopene, hawthorne extract, or combinations thereof. In certain embodiments, the composition is incorporated into pills. A method for promoting the brain pathways involved in sleep, relaxation, and calmness comprising: ingesting a composition comprising L-Tryptophan, L-Theanine, Reishi mushroom extract, Uridine, a polyphenol, and paeoniflorin. In one method, the composition is ingested at least one and a half hours before bedtime.