Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds containing both an amino acid functionality and multiple aromatic rings are disclosed of the general formula (1) where X is benzhydryl, or an aromatic or heteroaromatic ring.
Type:
Application
Filed:
May 14, 2008
Publication date:
January 8, 2009
Applicant:
Neuromed Phramaceuticals Ltd.
Inventors:
Robert Galemmo, JR., Richard Holland, Yanbing Ding, Lingyun Zhang, Gabriel Hum, Navjot Chahal, Joseph Duffy, Christian Stevenson, Andrew Ullman