Patents Assigned to Neuronautics, Inc.
  • Patent number: 6479528
    Abstract: Methods for inhibiting and/or reversing tau filament formation or polymerization are provided. These methods can be used for treating certain neurological disorders in vivo by administering pharmaceutical compositions which inhibit and/or reverse tau filament formation or polymerization. An especially preferred pharmaceutical composition contains an inhibitor of the general formula I wherein R1 is an aliphatic radical having one to six carbon atoms and wherein R2 and R3 independently are a second aliphatic radical having one to six carbon atoms, a hydroxyl-substituted aliphatic radical having one to six carbon atoms, or a pheny radical or a pharmaceutically acceptable salt of the inhibitor.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: November 12, 2002
    Assignee: Neuronautics, Inc.
    Inventors: Jeff Kuret, Sam Khatami