Abstract: An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.
Type:
Application
Filed:
October 21, 2024
Publication date:
April 23, 2026
Applicant:
NEURONOFF, INC.
Inventors:
Manfred Franke, Shaher Ahmad, Stephan Nieuwoudt, Amelia Howe, Aniruddha Upadhye, Emily Szabo, Derrick Liu, Sean Zuckermann, Craig Watson
Abstract: An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.
Type:
Application
Filed:
October 21, 2024
Publication date:
April 23, 2026
Applicant:
NEURONOFF, INC.
Inventors:
Manfred Franke, Shaher Ahmad, Stephan Nieuwoudt, Amelia Howe, Aniruddha Upadhye, Emily Szabo, Derrick Liu, Sean Zuckermann, Craig Watson
Abstract: A system for stimulating a tissue target in a body with an injectable electrode, either fully or partially implanted, may employ a protection device to prevent over-voltage or over-current from an external pulse generator (EPG) to the injectable electrode. Current is supplied from the EPG transcutaneously to the fully implanted injectable electrode and percutaneously to the partially implanted injectable electrode by various electrical connectors.
Abstract: An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.
Type:
Application
Filed:
March 27, 2025
Publication date:
July 31, 2025
Applicant:
NEURONOFF, INC.
Inventors:
Manfred Franke, Shaher Ahmad, Stephan Nieuwoudt, Amelia Howe, Aniruddha Upadhye, Emily Szabo, Derrick Liu, Sean Zuckermann, Craig Watson
Abstract: A system and associated methods for injection of a substantially linear and flexible medical device within a body. The system uses markings on a needle and on a plunger to guide the clinician in withdrawing a needle and advancing a plunger to create 3D anchors out of a substantially linear device.
Type:
Application
Filed:
February 3, 2023
Publication date:
May 1, 2025
Applicant:
NEURONOFF, INC.
Inventors:
STEPHAN NIEUWOUDT, ALAA ABD-ELSAYED, AMOL SOIN, EMILY SZABO, AMY HOWE, SHAHER AHMAD, JENNIFER PECK, KYLE GOLOBISH, MANFRED FRANKE
Abstract: An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.
Type:
Grant
Filed:
November 19, 2020
Date of Patent:
April 29, 2025
Assignee:
Neuronoff, Inc.
Inventors:
Manfred Franke, Shaher Ahmad, Stephan Nieuwoudt, Amelia Howe, Aniruddha Upadhye, Emily Szabo, Derrick Liu, Sean Zuckermann, Craig Watson
Abstract: A cured electrode comprising a mixture comprising conductive elements and a carrier which, upon injection into a body, cures from a liquid phase at a first time to a biocompatible solid phase at a second time at or on a target tissue within the body. The cured electrode is capable of being molded around contours of the target tissue so that, after curing, the cured electrode retains the contours of the target tissue. The cured electrode is capable of conducting electricity at a resistance of less than 10 ohm meters in the liquid or the solid phases. Carrier materials include hydgrogel, silicone, bone cement, cyanoacrylate, dental resin and a fibrin mix. The carrier material may also be used to anchor the cured electrode and provide great stability.
Type:
Grant
Filed:
June 12, 2019
Date of Patent:
April 9, 2024
Assignee:
NEURONOFF, INC.
Inventors:
Manfred Franke, Andrew Shoffstall, John W. Sheets, Jr.