Patents Assigned to Neurophyxia B.V.
  • 2-IMINOBIOTIN FOR USE IN THE TREATMENT OF STROKE
    Publication number: 20240173301
    Abstract: The invention relates to the field of medicine. In particular, the present invention relates to the use of 2-iminobiotin for use in the treatment of stroke, wherein 2-iminobiotin is administered in combination with a fibrinolytic drug. The invention in particular relates to the use of 2-iminobiotin for use in the treatment of acute ischemic stroke is due to vessel occlusion eligible for endovascular mechanical thrombectomy.
    Type: Application
    Filed: March 23, 2022
    Publication date: May 30, 2024
    Applicant: NEUROPHYXIA B.V.
    Inventors: Ido Remy VAN DEN WIJNGAARD, Cacha Marie Pétronelle Cathérine Dorothée PEETERS
  • 2-iminobiotin for use in the treatment of brain cell injury
    Patent number: 11426387
    Abstract: The present disclosure relates to the use of 2-iminobiotin for treating brain cell injury, in particular in adults. The treatment may be used for the treatment of cerebral hypoxia-ischemia and/or reperfusion injury, including one or more symptoms thereof. Provided are methods of treatment comprising administering a therapeutically effective dose of 2-iminobiotin to an individual in need thereof.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: August 30, 2022
    Assignee: Neurophyxia B.V.
    Inventors: Paul Willem Theresia Josef Leufkens, Cacha Marie Petronelle Catherine Dorothee Peeters, Huibert Alexander Tjabbes
  • 2-iminobiotin for use in the treatment of brain cell injury
    Patent number: 10722496
    Abstract: The present disclosure relates to the use of 2-iminobiotin for treating brain cell injury, in particular in adults. The treatment may be used for the treatment of cerebral hypoxia-ischemia and/or reperfusion injury, including one or more symptoms thereof. Provided are methods of treatment comprising administering a therapeutically effective dose of 2-iminobiotin to an individual in need thereof.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: July 28, 2020
    Assignee: Neurophyxia B.V.
    Inventors: Paul Willem Theresia Josef Leufkens, Cacha Marie Petronelle Catherine Dorothee Peeters, Huibert Alexander Tjabbes
  • 2-iminobiotin for use in the treatment of brain cell injury
    Patent number: 10525039
    Abstract: The present disclosure relates to the use of 2-iminobiotin for treating brain cell injury, in particular in adults. The treatment may be used for the treatment of cerebral hypoxia-ischemia and/or reperfusion injury, including one or more symptoms thereof. Provided are methods of treatment comprising administering a therapeutically effective dose of 2-iminobiotin to an individual in need thereof.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: January 7, 2020
    Assignee: Neurophyxia B.V.
    Inventors: Paul Willem Theresia Josef Leufkens, Cacha Marie Petronelle Catherine Dorothee Peeters, Huibert Alexander Tjabbes
  • 2-IMINOBIOTIN FOR USE IN THE TREATMENT OF BRAIN CELL INJURY
    Publication number: 20190262316
    Abstract: The present disclosure relates to the use of 2-iminobiotin for treating brain cell injury, in particular in adults. The treatment may be used for the treatment of cerebral hypoxia-ischemia and/or reperfusion injury, including one or more symptoms thereof. Provided are methods of treatment comprising administering a therapeutically effective dose of 2-iminobiotin to an individual in need thereof.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 29, 2019
    Applicant: Neurophyxia B.V.
    Inventors: Paul Willem Theresia Josef Leufkens, Cacha Marie Petronelle Catherine Dorothee Peeters, Huibert Alexander Tjabbes
  • 2-iminobiotin formulations and uses thereof
    Patent number: 9616135
    Abstract: The disclosure relates to improving the aqueous solubility of 2-iminobiotin. In a particular aspect, the disclosure pertains to formulations suitable for administration of 2-iminobiotin to mammals suffering from disorders or conditions that benefit from that administration.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: April 11, 2017
    Assignee: Neurophyxia B.V.
    Inventor: Paul W. T. J. Leufkens
  • 2-iminobiotin formulations and uses thereof
    Patent number: 9023878
    Abstract: The disclosure relates to improving the aqueous solubility of 2-iminobiotin. In a particular aspect, the invention pertains to formulations suitable for administration of 2-iminobiotin to mammals suffering from disorders or conditions that benefit from said administration.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: May 5, 2015
    Assignee: Neurophyxia B.V.
    Inventor: Paul W. T. J. Leufkens