Abstract: The invention provides methods for detection of medical disorders, associated with cellular oxidative stress, cell degeneration and/or cell death. The invention further relates to compounds comprising a thiol (—SH) group, for detecting cells undergoing oxidative stress, degeneration and/or a death process. The invention further provides methods for utilizing the compounds in medical practice, for diagnostic and therapeutic purposes.
Abstract: This invention provides new small-molecules capable of selective binding to membranes comprising and exposing phosphatidylserine on their surface and/or membranes which have increased amounts of phosphatidylethanolamine in their outer leaflet.