Abstract: Provided are novel methods comprising administering a therapeutically effective amount of (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane, in free or pharmaceutically acceptable salt form, to a patient in need thereof.
Type:
Application
Filed:
December 9, 2014
Publication date:
October 20, 2016
Applicant:
Neurovance, Inc.
Inventors:
Anthony MCKINNEY, Frank GENTILE, Timothy HSU, Franklin BYMASTER, Walter PISKORSKI, Richard WELTER
Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
Type:
Grant
Filed:
September 23, 2014
Date of Patent:
December 8, 2015
Assignee:
Neurovance, Inc.
Inventors:
Phil Skolnick, Anthony Basile, Zhengming Chen, Joseph W. Epstein
Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
Type:
Grant
Filed:
May 5, 2013
Date of Patent:
November 4, 2014
Assignee:
Neurovance, Inc.
Inventors:
Phil Skolnick, Anthony Basile, Zhengming Chen, Joseph W. Epstein
Abstract: The present invention relates to (1R,5S)-(+)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane and pharmaceutical compositions thereof, and methods employing their use in the treatment of conditions affected by monoamine neurotransmitters, including ADHD and substance abuse.
Type:
Application
Filed:
June 2, 2013
Publication date:
July 24, 2014
Applicant:
Neurovance, Inc.
Inventors:
Anthony Alexander McKINNEY, Frank Bymaster