Abstract: The present invention concerns immunogenic epitopes of Shigella-like toxins (SLTs), particularly the Shigella-like toxin of E. coli O157:H7, their use as immunogens and in treatment or diagnosis, agents (for example antibodies and antigen-binding fragments) which specifically neutralise them, their use in treatment and diagnosis, and methods for same.
Type:
Application
Filed:
May 30, 2002
Publication date:
April 3, 2003
Applicant:
NeuTech Pharma PLC
Inventors:
James Peter Burnie, Ruth Christine Matthews
Abstract: The present invention concerns immunogenic epitopes of Shigella-like toxins (SLTs), particularly the Shigella-like toxin of E. coli 0157:H7, their use as immunogens and in treatment or diagnosis, agents (for example antibodies and antigen-binding fragments) which specifically neutralise them, their use in treatment and diagnosis, and methods for same.
Type:
Grant
Filed:
January 20, 2000
Date of Patent:
June 25, 2002
Assignee:
NeuTech Pharma PLC
Inventors:
James Peter Burnie, Ruth Christine Matthews