Patents Assigned to Neutron Therapeutics, Inc.
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Publication number: 20230208130Abstract: An over-voltage protection system for an accelerator can include: a plurality of DC power supplies configured to provide a plurality of voltage levels up to a desired voltage level; and an acceleration tube electrically connected to the plurality of DC power supplies and configured to accelerate a charged particle. The acceleration tube can include a plurality of stages. Each stage can include a plurality of electrodes and a plurality of varistors configured to discharge energy in response to an overvoltage event. One electrode of the plurality of electrodes can be electrically coupled to a voltage level of the plurality of voltage levels. The plurality of electrodes and the plurality of varistors can be electrically coupled to each other and arranged in an alternating fashion.Type: ApplicationFiled: May 12, 2021Publication date: June 29, 2023Applicant: Neutron Therapeutics Inc.Inventors: Tyler R. Wills, William H. Park
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Patent number: 11589452Abstract: The present disclosures relates to an ion beam assembly where a relatively small deflection angle (approximately 15° from the center of the beam line) is used in conjunction with two beam dumps located on either side of the beam. In some embodiments, the combination of the two beam dumps and the magnet assembly can provide an ion beam filter. In some embodiments, the resulting system provides a smaller, safer and more reliable ion beam. In some embodiments, the ion beam can be a proton beam.Type: GrantFiled: May 5, 2017Date of Patent: February 21, 2023Assignee: Neutron Therapeutics, Inc.Inventors: Geoffrey Ryding, Takao Sakase, William H. Park, Theodore H. Smick
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Patent number: 11553584Abstract: Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.Type: GrantFiled: October 8, 2019Date of Patent: January 10, 2023Assignee: Neutron Therapeutics, Inc.Inventors: William H. Park, Jr., Mark Lambert, Joseph Gillespie, Noah Smick, Takao Sakase
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Publication number: 20210272716Abstract: Apparatuses and methods for producing neutrons for applications such as boron neutron capture therapy (BNCT) are described. An apparatus can include a rotary fixture with a coolant inlet and a coolant outlet, and a plurality of neutron-producing segments. Each neutron-producing segment of the plurality of neutron-producing segments is removably coupled to the rotary fixture, and includes a substrate having a coolant channel circuit defined therein and a solid neutron source layer disposed thereon. The coolant channel circuits are in fluid communication with the coolant inlet and the coolant outlet.Type: ApplicationFiled: May 3, 2021Publication date: September 2, 2021Applicant: Neutron Therapeutics Inc.Inventors: William H. Park, Jr., Steven P. Konish, Theodore H. Smick, Takao Sakase
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Patent number: 11024437Abstract: Apparatuses and methods for producing neutrons for applications such as boron neutron capture therapy (BNCT) are described. An apparatus can include a rotary fixture with a coolant inlet and a coolant outlet, and a plurality of neutron-producing segments. Each neutron-producing segment of the plurality of neutron-producing segments is removably coupled to the rotary fixture, and includes a substrate having a coolant channel circuit defined therein and a solid neutron source layer disposed thereon. The coolant channel circuits are in fluid communication with the coolant inlet and the coolant outlet.Type: GrantFiled: May 5, 2016Date of Patent: June 1, 2021Assignee: Neutron Therapeutics Inc.Inventors: William H. Park, Jr., Steven P. Konish, Theodore H. Smick, Takao Sakase
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Publication number: 20210120660Abstract: According to some embodiments, an electrostatic particle accelerator may include an assembly having a motor and support plate; an acceleration tube; one or more stage assemblies each having an alternator coupled to a common drive shaft, a power supply coupled to one of the plurality of electrodes, and an opening to receive a portion of the acceleration tube; a pressure vessel configured to enclose the acceleration tube when the pressure vessel is fastened to the support plate; and a circulator configured to pump high pressure gas into the pressure vessel. The acceleration tube can include an ion source, an extraction assembly, and a plurality of tube segments each having a plurality of electrodes and one or more power connectors attached to one of the electrodes.Type: ApplicationFiled: April 19, 2019Publication date: April 22, 2021Applicant: Neutron Therapeutics, Inc.Inventors: William H. Park, JR., Theodore H. Smick, Geoffrey Ryding, Ronald Horner
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Publication number: 20200196428Abstract: The present disclosures relates to an ion beam assembly where a relatively small deflection angle (approximately 15° from the center of the beam line) is used in conjunction with two beam dumps located on either side of the beam. In some embodiments, the combination of the two beam dumps and the magnet assembly can provide an ion beam filter. In some embodiments, the resulting system provides a smaller, safer and more reliable ion beam. In some embodiments, the ion beam can be a proton beam.Type: ApplicationFiled: May 5, 2017Publication date: June 18, 2020Applicant: Neutron Therapeutics, Inc.Inventors: Geoffrey RYDING, Takao SAKASE, William H. PARK, Theodore H. SMICK
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Publication number: 20200037430Abstract: Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.Type: ApplicationFiled: October 8, 2019Publication date: January 30, 2020Applicant: Neutron Therapeutics, Inc.Inventors: William H. Park, JR., Mark Lambert, Joseph Gillespie, Noah Smick, Takao Sakase
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Patent number: 10462893Abstract: Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.Type: GrantFiled: June 5, 2017Date of Patent: October 29, 2019Assignee: NEUTRON THERAPEUTICS, INC.Inventors: William H. Park, Jr., Mark Lambert, Joseph Gillespie, Noah Smick, Takao Sakase
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Patent number: 9887066Abstract: A system for controlling a high-power ion beam is disclosed, such as for steering, measuring, and/or dissipating the beam's power. In one embodiment, the ion beam can be controlled by being imparted into a cylindrical tube (e.g., a faraday cup), and deflected to strike an interior tube wall at an angle, thereby increasing an impact area of the beam on the wall. By also rotating the deflected beam around a circumference of the interior wall, the impact area of the ion beam may be further increased, thereby absorbing (dissipating) the high-power ion beam on the wall. In another embodiment, the ion beam may be passed through first, second, and third adjustable magnetic rings. By adjusting a relative angle between the rings and a combined rotation angle of all of the rings, a deflected ion beam may be rotated around a circumference of the interior wall of a power-absorbing tube, accordingly.Type: GrantFiled: July 8, 2015Date of Patent: February 6, 2018Assignee: NEUTRON THERAPEUTICS INC.Inventors: Geoffrey Ryding, Takao Sakase, Theodore Smick
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Patent number: 9883577Abstract: A continuous, thin layer of neutron source material, for example solid lithium, is formed into a belt. The belt is continuously advanced in front of a proton source to generate neutrons from the lithium target. Additionally, the belt is continuously cooled, as it passes through a gas cooling section. Through the continuous motion and cooling of the lithium target, the belt can provide an effective neutron source without melting the target neutron source material.Type: GrantFiled: April 24, 2017Date of Patent: January 30, 2018Assignee: Neutron Therapeutics, Inc.Inventors: Steven P. Konish, Theodore H. Smick