Abstract: Disclosed herein are embodiments of a electrochemical sensor device for rapidly determining whether a sample comprises analytes of interest. In particular embodiments, the analytes of interest are biomarkers associated with a physiological condition or disease. The electrochemical sensor device comprises a substrate-based platform having a working electrode comprising functionalized nanotubes that are functionalized with a metal ion and/or a polymer component. In some embodiments, the functionalized nanotubes comprise nanotubes prepared by a double anodization method that provides nanotubes having an average length greater than 3 ?m. In some additional embodiments, the substrate-based platform can comprise a substrate made of a fiber-based material.

Abstract: Tools adapted for spinal surgery are provided. More specifically, provided herein are apparatuses, systems, kits and methods for accurate, rapid and reliable placement of surgical cages or other medical implants in a patient's spine, and delivery of bone graft material thereto.

Abstract: A bone graft delivery system and method for using same to deliver graft material into a surgical site. The system includes an interbody implant having a securing site disposed on a surface of the implant and a holder having an elongated, hollow handle including a distal end. The distal end of the holder is configured to removably engage the securing site of the interbody implant to secure the interbody implant to the distal end of the holder until such time as a user desires to disengage the holder from the interbody implant. The interbody implant may be a cage implant having opposing anterior and posterior surfaces, opposing first and second lateral surfaces, and opposing top and bottom surfaces, wherein the top surface comprises a first aperture and the bottom surface comprises a second aperture, the posterior surface comprising a third aperture, the first, second, and third apertures all linking to a main cavity, the main cavity generally extending between the top surface and the bottom surface.

Abstract: Systems and methods are configured for power distribution in a hybrid fixed-wing VTOL drone aircraft. A drone aircraft includes two modes of operation. In a first mode of operation, the internal combustion engine is shut off while an electric motor-based VTOL system provides lift and thrust. In a second mode of operation, an internal combustion engine provides thrust while a set of fixed wings provide lift. In the second mode of operation, mechanical power from the internal combustion engine provides for power generation to charge an electrical battery to power the electric motor-based VTOL system.

Abstract: A system and method for identifying a customer's location within a facility or place of business, such as, but not limited to a casino. The system and method provides notification company representatives upon arrival of the customer at the given location. Additionally, the method and system allows for navigational services to be provided to customers, and real-time location determination, location tracking and confirmation to customers of location and rewards program status. The disclosed method and system can work through a system of wireless radio, sound and/or light-based beacons communicating with the customer's smartphone, computer system, or other electronic device.

Abstract: A composite core assembly includes a composite core structure having internal material interfaces and an attachment rail coupled to the composite core structure. The attachment rail includes a first planar surface and a second planar surface adjoined with the first planar surface. The first planar surface is arranged parallel to an internal material interface plane of the composite core structure, and the first planar portion is at least partially integrated into the composite core structure in an internal material interface plane. At least a portion of the first planar surface extends beyond a perimeter surface of the composite core structure, and the second planar surface is configured to attach to the surrounding support member. The core material does not have net edge facets or flat edges positioned next to surrounding structure, and/or may not have a structure arranged parallel to the adjacent support structure to attach to the support structure.

Abstract: A steerable beam antenna includes a plurality of semiconductor chips arranged along a longitudinal axis. Each of the chips has a ground plane on its upper surface, and is doped to form an array of semiconductor switches arranged along the longitudinal axis. A corresponding array of scattering elements, each having a first leg and a second leg, is mounted on each chip along the longitudinal axis. A first electrode of each switch is configured for connection to a control circuit, a second electrode is connected to the ground plane, and a third electrode is connected to the first leg of one of the array of scattering elements, the second leg of which is connected to the ground plane. A dielectric element is mounted on the antenna chips along the longitudinal axis above the arrays of switches and scattering elements and is separated from the scattering elements by an air gap.

Abstract: A system and method for identifying a customer's location at a business and provide notification to a company representative upon arrival of the customer at the business location. Real-time location determinations for the customer and customer location tracking can be provided. One or more wireless beacons communicate with the customer's electronic device. The beacons provide the system with real-time data about the customer's whereabouts, allowing for the confirmation and tracking of the customer at the location. A first non-limiting example of use, include a company that provides food and beverage allowing the customer to place an order for food and beverages on their electronic device and having the order delivered to the person at their current location as determined by the system. Another non-limiting example includes a company using the notification system to have assigned staff members notified of the customer's arrival.

Abstract: Provided herein are diaryl and arylalkyl phosphonates, useful as intermediates in, for example, the synthesis of leukocyte elastase inhibitors, potassium channel modulators, chemiluminescence materials, and flame retardants, and methods for making same. Also provided are N-heterocyclic phosphorodiamidic acids (NHPAs) useful in reactions such as, for example, in the preparation of diaryl and arylalkyl phosphonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Disclosed herein are embodiments of a molybdate-based composition and a conversion coating obtained therefrom that can replace conventional and toxic chromate-based conversion coatings in a variety of applications and industries. The molybdate-based composition provides conversion coatings that exhibit anodic inhibition and rapid repassivation when applied to objects, such as metal-based objects, and do not contain hexavalent chromium. The molybdate-based composition and conversion coating can be used to reduce corrosion. Embodiments of methods of protecting objects, such as metal surfaces, with the molybdate-based conversion coating also are disclosed.

Abstract: An unmanned aerial vehicle includes a fuselage having a first side and a second side, a first arm disposed on a first side of the fuselage, wherein the first arm is coupled to one or more first propellers, wherein the first arm is adapted to move between a first folded position in which the first arm is in a folded state inside the fuselage and a first extended position in which a first section of the first arm and the one or more first propellers are outside the fuselage, and a second arm disposed on the second side of the fuselage, wherein the second arm is coupled to one or more second propellers, wherein the second arm is adapted to move between a second folded position in which the second arm is in a folded state inside the fuselage and a second extended position in which a second section of the second arm and the one or more second propellers are outside the fuselage.

Abstract: Systems, methods, and devices for monitoring operation of industrial equipment are disclosed. In one embodiment, a monitoring system is provided that includes a passive backplane and one more functional circuits that can couple to the backplane. Each of the functional circuits that are coupled to the backplane can have access to all data that is delivered to the backplane. Therefore, resources (e.g., computing power, or other functionality) from each functional circuits can be shared by all active functional circuits that are coupled to the backplane. Because resources from each of the functional circuits can be shared, and because the functional circuits can be detachably coupled to the backplane, performance of the monitoring systems can be tailored to specific applications. For example, processing power can be increased by coupling additional processing circuits to the backplane.

Abstract: A VTOL drone aircraft can include a rechargeable battery, a primary processor, lift propellers, an internal combustion engine with a thrust propeller, a generator, and a power regulation controller. The generator can receive power from the internal combustion engine and deliver electrical power to the rechargeable battery, the lift propellers, or both. The power regulation controller can regulate dynamically power delivery from the internal combustion engine to the thrust propeller and the generator, and from the generator to the rechargeable battery based upon changing conditions during flight. The power regulation controller can prevent operation of the generator when peak power is needed from the internal combustion engine for the thrust propeller. The power regulation controller can also control a clutch coupled to the thrust propeller to regulate the delivery of power to the thrust propeller when the internal combustion engine is active.

Abstract: Superconductive materials and methods of making the same are described, in which the superconductive materials are grown on a crystalline substrate having lattice parameters that impart a strain on the superconductive materials that reduces an applied pressure at which the superconductive materials exhibit superconductivity.

Abstract: A gap compensated stress sensing system and methods for using the same are provided. The system can include a sensor head in communication with a controller. The sensor head can contain a stress sensor configured to generate a stress signal representing stress applied to a target based upon measurement of generated magnetic fluxes passing through the target. The system can also include a drive circuit configured to provide a current for generation of the magnetic fluxes, and to measure signals characterizing a gap between the sensor head and the target. The controller can analyze these signals to determine a gap-dependent reference signal that is relatively insensitive to electrical runout. The controller can further adjust the stress signal based upon the gap-dependent reference signal to determine an improved stress signal that has reduced sensitivity to gap changes.

Abstract: The present disclosure relates to kits for bone graft delivery, and specifically, for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The kits include integrated fusion cage and graft delivery devices that deliver and disperse biologic material through a fusion cage to a disc space and, that may, without withdrawal from the surgical site, allow for selectively detaching the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. The kits also include a cover plate that secures to the fusion cage.

Abstract: One aspect of the invention provides a computer-implemented method of identifying a species from mass spectra. The computer-implemented method includes: loading a data set including a species and associated mass spectra into memory on a computer; for each of the associated mass spectra, pre-processing to identify ranks of intensities of an in-bin peak across bins defining ranges of mass-to-charge ratio; and training a species binary classifier for each of a plurality of species using at least the ranks of intensities. Another aspect of the invention provides a system for identifying a species from mass spectra. The system includes: a processor; and computer-readable memory containing instructions to: implement an interface programmed to receive mass spectra; store the mass spectra in the computer-readable memory; and invoke execution of any of the methods described herein on the processor.

Abstract: A method of treating a patient to reduce risk of developing Clostridium difficile-associated disease or reducing existing Clostridium difficile-associated disease in a mammalian subject involves administering to a mammalian subject an effective amount of a germination-inhibiting compound derived from taurocholate. Novel compounds of this class are also provided.