Patents Assigned to New England Deacons Hospital Corp.
  • CEA-binding protein and uses thereof
    Patent number: 5281697
    Abstract: Disclosed is a protein that specifically binds carcinoembryonic actigen (CEA) in the presence of divalent cation in vitro. This protein has a molecular weight of about 20 kD as determined by SDS-polyacrylamide gel electrophoresis, is glycosylated, and includes the amino acid sequence set forth in the Sequence Listing as SEQ ID NO:4. Also disclosed are antibodies that recognize the CEA binding protein, methods of detecting carcinoma, methods of treating carcinoma, and a kit for screening a patient for carcinoma.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: January 25, 1994
    Assignees: Applied Biotechnology, Inc., New England Deacons Hospital Corp.
    Inventors: Carol A. Toth, Peter Thomas, Sibusisiwe M. Maswoswe, Joseph V. Briggman