Abstract: The present disclosure provides pharmaceutical compositions for treating fungal and bacterial infections. The pharmaceutical compositions of the disclosure comprise a cationic surfactant, a chelating agent, and at least one solvent. The pharmaceutical compositions of the disclosure can be used to treat drug-sensitive or multi drug-resistant bacterial or fungal infections.

Abstract: Disclosed herein are methods of treating a cancer that overexpresses NQO1 comprising administering KP372-1. In some embodiments, KP372-1 is administered with a polymerase inhibitor.

Abstract: The present disclosure describes a method of treating an infection, including a parasitic infection, using compounds of the invention. The compounds of the invention can selectively eradicate intracellular mammalian and human parasites.

Abstract: Disclosed herein is a composition and a method for energy harvesting and the autonomous detection of structural failure. This method can be used to monitor, for example, the structural integrity of unmanned aircraft systems.

Abstract: The disclosure provides a Sn—In electroplating bath that is Pb-free, environmentally safe, operates at room temperature, and does not require changes in existing plating assemblies. Room temperature aging and limited thermal cycling tests show that the electroplated Sn—In alloy film on a Cu substrate effectively mitigates whisker growth.

Abstract: The present disclosure provides pharmaceutical compositions for treating fungal and bacterial infections. The pharmaceutical compositions of the disclosure comprise a cationic surfactant, a chelating agent, and at least one solvent. The pharmaceutical compositions of the disclosure can be used to treat drug-sensitive or multi drug-resistant bacterial or fungal infections.

Abstract: The disclosure provides proteasome inhibitors that can be used to halt cell division of rapidly dividing cells by preventing the degradation of cell cycle-regulating proteins, such as cyclins, cyclin-dependent kinase inhibitors, and p53. The proteasome inhibitor compounds can be used to inhibit the proliferation of cancer cells.

Abstract: Disclosed herein is a composition and a method for energy harvesting and the autonomous detection of structural failure. This method can be used to monitor, for example, the structural integrity of unmanned aircraft systems.

Abstract: The present disclosure describes a method of separating particles using a combination of acoustophoresis and acoustic fluid relocation. The disclosure also describes a microfluidic device that can be used to separate particles using a combination of acoustophoresis and acoustic fluid relocation. The disclosure describes methods of separating nanoparticles, microparticles, nanoparticles from microparticles, and micron-sized particles from sub-micron-sized particles.

Abstract: The present disclosure describes a system and method of depositing ceramic or ceramic composite coatings on the inside surface area of a tubular shape. The system and method described herein can provide an interior coating for tubes and pipes to provide wear resistance, abrasion resistance, and anti-scaling effects.

Abstract: An Impact sensor for detecting strain or strain rate in a composite having one or more sensor nodes using a fracto-mechanoluminescent (FML) material, such as EuD4TEA crystals, encased in an optically transparent material such as PDMS. Optical fibers transmit light emitted by the FML material due to strain experienced by the composite. For honeycomb composites, the transparent material is disposed within cells of the honeycomb composite. A reflective material such as Mylar either surrounds the optically transparent material or lines the cell. The intensity of the light emitted by the FML material is related to the magnitude of strain or strain rate experienced by the composite as well as the distance of the FML material from the surface of the composite that receives the impact. Multiple sensor nodes disposed at different distances from the impact surface can provide a three-dimensional map of damage experienced by the composite.

Abstract: The present disclosure describes a method to treat conditions, including cancer, using compounds that can target resistant cancer cells. The compounds of the invention can decrease the rate of proliferation of drug-resistant cancer cells, such as glioma, lung cancer, and uterine sarcoma.

Abstract: The present disclosure describes a method to treat conditions, including bacterial infections and cancer, using a photosensitive compound that, upon exposure to white light, can be activated. The photosensitive compound can also interact synergistically with antibiotics used concomitantly to kill drug-resistant bacteria. The photosensitive compounds can also be used to inhibit the proliferation of cancer cells.