Patents Assigned to New York Blood Center
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Publication number: 20240018471Abstract: Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof.Type: ApplicationFiled: June 6, 2023Publication date: January 18, 2024Applicants: THE CHILDREN'S HOSPITAL OF PHILADELPHIA, NEW YORK BLOOD CENTER, INC.Inventors: Stella CHOU, Connie WESTHOFF
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Patent number: 11834757Abstract: The present specification provides libraries of HLA homozygous induced pluripotent cell lines.Type: GrantFiled: December 5, 2018Date of Patent: December 5, 2023Assignee: New York Blood Center, Inc.Inventors: Pablo Rubinstein, Christopher D. Hillyer
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Patent number: 11831705Abstract: A system, method, and apparatus for transferring blood donation files are disclosed. An example system includes a collection device located at a blood donation site and a collection server located in a remote location. The example collection device is configured to store blood donation information from blood donors within a blood donation batch file located at a designated directory of a memory, and store metadata related to the blood donation information to the blood donation batch file. The example collection device also transmits the blood donation batch file to a registered user device. The example collection server is configured to determine the registered user device is available via a network connection. Responsive to determining the user device is connected, the collection server acquires the blood donation batch file from the user device and aggregates the blood donation batch file with blood donation batch files received from other registered user devices.Type: GrantFiled: July 11, 2022Date of Patent: November 28, 2023Assignee: New York Blood Center, Inc.Inventor: Sabyasachi Sarkar
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Patent number: 11708559Abstract: Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof.Type: GrantFiled: October 29, 2018Date of Patent: July 25, 2023Assignees: The Children's Hospital of Philadelphia, New York Blood Center, Inc.Inventors: Stella Chou, Connie Westhoff
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Patent number: 11571409Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: December 8, 2020Date of Patent: February 7, 2023Assignee: New York Blood Center, Inc.Inventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 11388221Abstract: A system, method, and apparatus for transferring blood donation files are disclosed. An example system includes a collection device located at a blood donation site and a collection server located in a remote location. The example collection device is configured to store blood donation information from blood donors within a blood donation batch file located at a designated directory of a memory, and store metadata related to the blood donation information to the blood donation batch file. The example collection device also transmits the blood donation batch file to a registered user device. The example collection server is configured to determine the registered user device is available via a network connection. Responsive to determining the user device is connected, the collection server acquires the blood donation batch file from the user device and aggregates the blood donation batch file with blood donation batch files received from other registered user devices.Type: GrantFiled: March 1, 2021Date of Patent: July 12, 2022Assignee: New York Blood Center, Inc.Inventor: Sabyasachi Sarkar
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Publication number: 20220001006Abstract: The present disclosure provides virus like nanoparticles (VLPs), which are capable of displaying multiple copies of a SARS-CoV-2 antigen, for eliciting protective immunity against a SARS-CoV-2 infection, as well as polypeptides, compositions and methods thereof.Type: ApplicationFiled: June 29, 2021Publication date: January 6, 2022Applicants: Regents of the University of Minnesota, New York Blood Center, Inc.Inventors: Frank Jonathan Lee, Qibin Geng, Jian Shang, Marc Jenkins, Sung-Wook Hong, Lanying Du, Wanbo Tai, Yushun Wan
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Publication number: 20210355440Abstract: Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof.Type: ApplicationFiled: October 29, 2018Publication date: November 18, 2021Applicants: THE CHILDREN'S HOSPITAL OF PHILADELPHIA, NEW YORK BLOOD CENTER, INC.Inventors: Stella CHOU, Connie WESTHOFF
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Patent number: 11103575Abstract: Described herein are immunogenic compositions for preventing infection with Middle East respiratory syndrome coronavirus (MERS-CoV) wherein the immunogenic compositions comprise at least a portion of the MERS-CoV S protein and an immunopotentiator.Type: GrantFiled: November 17, 2017Date of Patent: August 31, 2021Assignee: The New York Blood Center, Inc.Inventors: Lanying Du, Fang Li, Shibo Jiang, Yusen Zhou
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Patent number: 11059808Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: August 23, 2016Date of Patent: July 13, 2021Assignees: New York Blood Center, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human ServicesInventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 10938885Abstract: A system, method, and apparatus for transferring blood donation files are disclosed. An example system includes a collection device located at a blood donation site and a collection server located in a remote location. The example collection device is configured to store blood donation information from blood donors within a blood donation batch file located at a designated directory of a memory, and store metadata related to the blood donation information to the blood donation batch file. The example collection device also transmits the blood donation batch file to a registered user device. The example collection server is configured to determine the registered user device is available via a network connection. Responsive to determining the user device is connected, the collection server acquires the blood donation batch file from the user device and aggregates the blood donation batch file with blood donation batch files received from other registered user devices.Type: GrantFiled: April 5, 2017Date of Patent: March 2, 2021Assignee: New York Blood Center, Inc.Inventor: Sabyasachi Sarkar
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Patent number: 10869856Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: January 30, 2020Date of Patent: December 22, 2020Assignees: New York Blood Center, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human ServicesInventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 10612000Abstract: The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from a plurality of blood units, and inactivating any pathogen contained therein. A storage solution added to the cellular component results in a cell-containing product that is essentially pathogen and white blood cell free and has an extended shelf life of about 42 to about 100 days. The cell-containing product is further divided into units which comprise a uniform dose of RBCs per unit.Type: GrantFiled: May 2, 2018Date of Patent: April 7, 2020Assignee: New York Blood Center, Inc.Inventors: Beth H. Shaz, Christopher D. Hillyer
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Patent number: 10576059Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: July 24, 2019Date of Patent: March 3, 2020Assignees: New York Blood Center, Inc., The United States of America, as Represented by the Secretary, Department of Human ServicesInventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 10413527Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: November 1, 2018Date of Patent: September 17, 2019Assignees: New York Blood Center, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human ServicesInventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 10385317Abstract: The disclosure provides methods of making a red blood cell, plasma, and platelet products having a uniform dose and volume. The method comprises pooling a plurality of blood units, leukoreducing the blood and inactivating any pathogen contained therein. Plasma, RBCs, and platelets are then divided into uniform dose and volume units which have an extended shelf life.Type: GrantFiled: May 30, 2012Date of Patent: August 20, 2019Assignee: NEW YORK BLOOD CENTER, INC.Inventors: Beth Shaz, Christopher D. Hillyer
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Patent number: 10137107Abstract: Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.Type: GrantFiled: September 18, 2015Date of Patent: November 27, 2018Assignees: New York Blood Center, Inc., National Institutes of HealthInventors: Asim Kumar Debnath, Francesca Curreli, Peter D. Kwong, Young Do Kwon
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Patent number: 9982230Abstract: The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from a plurality of blood units, and inactivating any pathogen contained therein. A storage solution added to the cellular component results in a cell-containing product that is essentially pathogen and white blood cell free and has an extended shelf life of about 42 to about 100 days. The cell-containing product is further divided into units which comprise a uniform dose of RBCs per unit.Type: GrantFiled: June 13, 2016Date of Patent: May 29, 2018Assignee: NEW YORK BLOOD CENTER, INC.Inventors: Beth H. Shaz, Christopher D. Hillyer
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Patent number: 9943589Abstract: Disclosed herein are immunogenic compositions for preventing infection with influenza viruses wherein the immunogenic compositions comprises an immunogen such as a hemagglutinin of an influenza virus, and an immunopotentiator such as an Fc fragment of human IgG and optionally a stabilization sequence. The immunogen is linked to the stabilization sequence which in turn is linked to the immunopotentiator.Type: GrantFiled: January 26, 2017Date of Patent: April 17, 2018Assignee: NEW YORK BLOOD CENTER, INC.Inventors: Shibo Jiang, Lanying Du
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Patent number: 9889194Abstract: Described herein are immunogenic compositions for preventing infection with Middle East respiratory syndrome coronavirus (MERS-CoV) wherein the immunogenic compositions comprise at least a portion of the MERS-CoV S protein and an immunopotentiator.Type: GrantFiled: February 28, 2014Date of Patent: February 13, 2018Assignee: New York Blood Center, Inc.Inventors: Shibo Jiang, Lanying Du, Yusen Zhou, Guangyu Zhao