Patents Assigned to New York Hospital-Cornell Medical Center
  • Small cell lung cancer associated antigens and uses therefor
    Patent number: 7314721
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with small cell lung cancer. The invention provides, among other things, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: January 1, 2008
    Assignees: Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York Hospital-Cornell Medical Center
    Inventors: Ali O. Gure, Elisabeth Stockert, Matthew J. Scanlan, Dirk Jager, Lloyd J. Old, Yao-Tseng Chen
  • Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and treating colon cancer
    Patent number: 6982316
    Abstract: Various molecules associated with disorders such as cancer are disclosed. The invention also discloses diagnostic aid therapeutic methods based upon these molecules, as well as compositions for stimulating an immune response and methods for identifying cancer-associated nucleic acid and polypeptide molecules.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: January 3, 2006
    Assignees: Ludwig Institute for Cancer Research, The New York Hospital-Cornell Medical Center
    Inventors: Matthew J. Scanlan, Yao-Tseng Chen, Elisabeth Stockert, Lloyd J. Old
  • Renal cancer associated antigens and uses therefor
    Patent number: 6440663
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in renal cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with renal cancer. The invention provides, inter alia, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided. The molecules provided by the invention can be used in the diagnosis, monitoring, research, or treatment of conditions characterized by the expression of one or more cancer associated antigens.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: August 27, 2002
    Assignees: Ludwig Institute for Cancer Research, The New York Hospital-Cornell Medical Center
    Inventors: Matthew J. Scanlan, Elisabeth Stockert, Yao-Tseng Chen, Lloyd J. Old, Elke Jager, Alex Knuth