Patents Assigned to Newtree Co., Ltd.
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Patent number: 11622984Abstract: The present invention relates to a composition comprising Aster sphathulifolius Maxim extract for preventing, improving, or treating muscular diseases and for improving muscular functions. The Aster sphathulifolius Maxim extract according to the present invention exhibits effects of inhibiting the expression of muscle protein breakdown-related factors and increasing the expression of muscle protein synthesis-related factors, as well as alleviating the reduction of muscle tissue weight and cross-sectional area of muscle fibers, and thus can be useful for preventing, improving, or treating muscular diseases and improving muscular functions.Type: GrantFiled: May 20, 2019Date of Patent: April 11, 2023Assignee: NEWTREE CO., LTD.Inventors: Woo Chang Jung, Do Un Kim, Hee Chul Chung
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Patent number: 10960040Abstract: The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing a Platycodon grandiflorum extract. More specifically, the present invention relates to: a pharmaceutical composition for preventing and treating muscle diseases, containing a Platycodon grandiflorum extract; a food composition for preventing muscle diseases or improving muscular function; or a cosmetic for improving muscular function. The Platycodon grandiflorum extract of the present invention increases muscle formation by inducing muscular protein synthesis and muscle cell differentiation. Therefore, the extract is a natural product so as to be used safely without side effects, thereby being usable as an active ingredient of a pharmaceutical, food, or cosmetic composition exhibiting an excellent effect in preventing and treating muscle diseases or improving muscular function.Type: GrantFiled: May 26, 2016Date of Patent: March 30, 2021Assignee: NEWTREE CO., LTD.Inventors: Jae-Kwan Hwang, Mi-Bo Kim, Changhee Kim, Doun Kim, Heechul Chung
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Patent number: 10821153Abstract: Vigna angularis var. angularis according to the present invention is capable of increasing muscle mass and enhancing muscular function or exercise performance through an effect of promoting mRNA or protein expression and the activity of a gene involved in muscle functions, muscle mass increase of differentiation of muscle cells; can prevent, treat or ameliorate a decline in exercise performance, a decline in muscle function, muscle loss, etc. caused by various diseases; and may be effectively used for medicines or food products, etc., since it has no side effects in the body as natural substance.Type: GrantFiled: May 2, 2017Date of Patent: November 3, 2020Assignee: NEWTREE CO., LTD.Inventors: Jae Kwan Hwang, Se In Lee, Mi Bo Kim, Chang Hee Kim, Doun Kim, Heechul Chung, Hyeongmin Kim
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Patent number: 10576057Abstract: The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing, as an active ingredient, at least one selected from the group consisting of morusin, kuwanon G, and a Mori Cortex Radicis extract. The Mori Cortex Radicis extract, morusin, or kuwanon G, according to the present invention, has an effect of remarkably enhancing muscular function by increasing the expression of p-mTOR protein involved in muscular protein synthesis, inhibiting the expression of mRNAs of MuRF-1 and atrogin-1 involved in muscular protein degradation, and increasing the expression of mRNAs of MyoD and myogenin involved in muscular differentiation. In addition, the present invention is a natural product so as to be used safely without side effects, thereby being usable in drugs, food, or cosmetics.Type: GrantFiled: November 27, 2017Date of Patent: March 3, 2020Assignee: NEWTREE CO., LTD.Inventors: Jae-Kwan Hwang, Mi-Bo Kim, Changhee Kim, Doun Kim, Heechul Chung
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Patent number: 9452193Abstract: The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue and enhancing exercise performance, and more particularly to a composition for promoting an increase in muscles, anti-fatigue composition and a composition for enhancing muscle mass growth and recovery from fatigue to improve exercise performance, the composition comprising a panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata as an active ingredient, and to a method for enhancing muscle mass growth, of treating or preventing fatigue syndrome and enhancing exercise performance, the method comprising a panduratin derivative or a salt thereof or a extract of Boesenbergia pandurata to a subject in need thereof.Type: GrantFiled: September 4, 2015Date of Patent: September 27, 2016Assignees: Biocare Co., Ltd., Newtree Co., Ltd.Inventors: Jae-Kwan Hwang, Do Un Kim
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Patent number: 9198880Abstract: The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue and enhancing exercise performance. A panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-? in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.Type: GrantFiled: November 20, 2012Date of Patent: December 1, 2015Assignees: Biocare Co., Ltd., Newtree Co., Ltd.Inventors: Jae-Kwan Hwang, Do Un Kim
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Patent number: 8969408Abstract: The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.Type: GrantFiled: October 17, 2008Date of Patent: March 3, 2015Assignees: Biocare Co., Ltd., Newtree Co., Ltd.Inventors: Jae Kwan Hwang, Yu-Mi Cho, Gyu Hoi Kim, Jeong Hwan Kim, Hae Ji Lee, Do Un Kim, Hee Chul Chung, Jae Youn Chung, Hyun In Oh
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Patent number: 8653143Abstract: The present invention relates to a novel use of a panduratin derivative or a Boesenbergia pandurata extract. More specifically, the invention relates to a composition for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, containing a panduratin derivative represented by Chemical Formula 1, 2 or 3 or a Boesenbergia pandurata extract as an active ingredient, a method for treating a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, by administering an effective amount of the panduratin derivative or the Boesenbergia pandurata extract to a subject in need thereof, and a use of the panduratin derivative or the Boesenbergia pandurata extract to prepare a reagent for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes.Type: GrantFiled: October 9, 2009Date of Patent: February 18, 2014Assignees: Newtree Co., Ltd.Inventors: Jae-Kwan Hwang, Do Un Kim
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Publication number: 20130344182Abstract: The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue and enhancing exercise performance. A panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-? in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.Type: ApplicationFiled: November 20, 2012Publication date: December 26, 2013Applicants: NEWTREE CO., LTD., BIOCARE CO., LTD.Inventors: Biocare Co., Ltd., Newtree Co., Ltd.
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Patent number: 8435957Abstract: The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.Type: GrantFiled: June 20, 2008Date of Patent: May 7, 2013Assignees: Biocare Co., Ltd., Newtree Co., Ltd.Inventors: Jae-Kwan Hwang, Hae Ji Lee, Jae Young Lee, Jae-Seok Shim, Jeong Hwan Kim, Do Un Kim, Heechul Chung, Jae Youn Chung
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Publication number: 20120088840Abstract: The present invention relates to a novel use of a panduratin derivative or a Boesenbergia pandurata extract. More specifically, the invention relates to a composition for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, containing a panduratin derivative represented by Chemical Formula 1, 2 or 3 or a Boesenbergia pandurata extract as an active ingredient, a method for treating a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, by administering an effective amount of the panduratin derivative or the Boesenbergia pandurata extract to a subject in need thereof, and a use of the panduratin derivative or the Boesenbergia pandurata extract to prepare a reagent for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes.Type: ApplicationFiled: October 9, 2009Publication date: April 12, 2012Applicants: JAE-KWAN HWANG, NEWTREE CO., LTD.Inventors: Jae-Kwan Hwang, Do Un Kim
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Publication number: 20120065272Abstract: The present invention relates to a new use of panduratin derivatives or a Kaempferia pandurata extract comprising the same. More particularly, the present invention relates to a composition for improving wrinkles and/or preventing aging, which comprises a panduratin derivative or a Kaempferia pandurata extract comprising the same. The said the panduratin derivative or the Kaempferia pandurata extract comprising the same induces cell proliferation, inhibits degradation of collagen, and promotes synthesis of collagen, therefore, it shows excellent activity in prevention of aging, particularly preventing, improving or treating wrinkle and it can be used as an effective ingredient in a cosmetic, food or pharmaceutical composition.Type: ApplicationFiled: October 17, 2008Publication date: March 15, 2012Applicant: NEWTREE CO., LTD.Inventors: Jae Kwan Hwang, Jae-Seok Shim, Song Hui Gwon, Yi Young Kwon, Hyun In Oh, Young Sun Han, Eun Jung Choi, Do Un Kim
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Publication number: 20110118346Abstract: The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.Type: ApplicationFiled: October 17, 2008Publication date: May 19, 2011Applicants: BIOCARE CO., LTD., NEWTREE CO., LTD.Inventors: Jae Kwan Hwang, Yu-Mi Cho, Gyu Hoi Kim, Jeong Hwan Kim, Hae Ji Lee, Do Un Kim, Hee Chul Chung, Jae Youn Chung, Hyun In Oh
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Patent number: 7902254Abstract: Disclosed is a method for treating PPAR (peroxisome proliferator activated receptor)-mediated diseases, such as diabetes mellitus, which includes administering to a subject an effective amount of macelignan represented by the following Formula (I): or a pharmaceutically acceptable salt thereof.Type: GrantFiled: June 27, 2006Date of Patent: March 8, 2011Assignee: Newtree Co., Ltd.Inventors: Jae-Kwan Hwang, Kyu-Lee Han, Jong-Hee Sohn, Ah-Jin Kim, Jeong-Han Choo, Jae-Young Lee, Jeong-Hwan Kim, Do Un Kim, Heechul Chung, Jae Youn Chung