Abstract: The present invention describes a recombinant retroviral vector which cannot by itself achieve complete reverse transcription as well as its uses, in particular for transiently transferring in vitro, ex vivo or in vivo at least one ribonucleic acid sequence of interest in a cell. Such a transient transgene expression is of interest in the context of research, therapy and more generally in the field of biotechnology.
Type:
Grant
Filed:
October 26, 2012
Date of Patent:
June 4, 2019
Assignee:
NEWVECTYS
Inventors:
Chamsy Sarkis, Dorothee Altemir, Nicolas Grandchamp, Stephanie Philippe