Patents Assigned to NeXstar Pharmaceticals, Inc.
  • Systematic polypeptide evolution by reverse translation
    Patent number: 5843701
    Abstract: A method for preparing polypeptide ligands of target molecules wherein candidate mixtures comprised of ribosome complexes or mRNA.multidot.polypeptide copolymers are partitioned relative to their affinity to the target and amplified to create a new candidate mixture enriched in ribosome complexes or mRNA.multidot.polypeptide copolymers with an affinity to the target.
    Type: Grant
    Filed: January 31, 1992
    Date of Patent: December 1, 1998
    Assignee: NeXstar Pharmaceticals, Inc.
    Inventors: Larry Gold, Craig Tuerk, David Pribnow, Jonathan Drew Smith