Abstract: In an illustrative embodiment, a dual mode, high-sensitivity, and low-cost applicator array based on split-ring resonators (SRR) and microstrip coupled lines serves as both an imaging and treatment tool for skin cancers. The applicator array consists of 3×3 unit cells, in which each unit in a row is tuned to a separate frequency, ranging from 8 to 15 GHz (unloaded). Via fences surrounding the unit cells provide E-field shielding and enhance resonance. The excitation is coupled magnetically from microstrip to SRRs and generates strong E-fields across the gap between SRR loop terminals. By observing the resonance shift and attenuation under different material under test (MUT), skin in one case, permittivity differences can be analyzed to distinguish malignancies from healthy tissue. Using the same applicator array, hyperthermia capability requires less than 5 W of power to cause significant temperature elevation.