Abstract: Provided is a facial patch including a support, a pressure-sensitive adhesive layer, and a release layer in this order, in which (a) the pressure-sensitive adhesive layer satisfies the following conditions (a-1) to (a-3): (a-1) the pressure-sensitive adhesive layer contains a styrene-isoprene-styrene block copolymer, a tackifier resin, and a softening agent; (a-2) the ratio (mass ratio) of the styrene-isoprene-styrene block copolymer and the tackifier resin is 1:2 to 1:4; and (a-3) the content of the softening agent is 40% to 60% by mass; and (b) the support has elastic moduli with a Young's modulus of 0.01 GPa to 0.5 GPa, and also provided is a method for producing the facial patch, the method including a step of forming a pressure-sensitive adhesive layer on the upper surface of the release layer.

Abstract: A binding device that prevents damage to binding tape including a biodegradable material as a base material comprises a pressing surface formed on a resin attachment which is detachably mounted on a head of a tape holding plate, and therefore it is possible to mount an attachment of a shape and material suitable for binding tape to be used. Furthermore, because the tape receiving plate is formed by a rubber plate, the tape receiving plate is able to absorb a shock generated by the pointed end of the tape holding plate entering the tape receiving plate. With this arrangement, it possible to prevent damage to fragile binding tape including a biodegradable material as a base material.

Abstract: A sterile packaging container that can smoothly and repeatedly accommodate housed medicine without increasing the risk of contamination includes a front side film, and a back side film. An opening is formed on one side, and two sides and a bottom are heat sealed. The front side film is a non-breathable film with a strip of breathable sterile paper interposed and extending in the width direction. The backside film is composed of a non-breathable film. In the front side film, the vertical edges of the non-breathable film and the vertical edges of the breathable sterile paper have a structure in which they are heat-sealed to each other. All contact parts of the non-breathable film and the breathable sterile paper are heat sealed.

Abstract: A nonaqueous adhesive skin patch at least comprises a backing film and an adhesive layer placed thereabove, the adhesive layer containing a local anesthetic, wherein when the total mass of an adhesive is set to 100% by mass, the adhesive layer includes the following in the ratio of: 20 to 40% by mass of an elastomer; 20 to 35% by mass of a softener; 20 to 40% by mass of a resin; 3.0 to 7.0% by mass of the local anesthetic; and 0.3 to 4.0% by mass of organic acid, and wherein the adhesive layer has a mass per unit area of 100 to 200 g/m2.

Abstract: A method for manufacturing adhesive resin pellets includes adding an antiblocking agent to water, melting an adhesive resin and extruding the adhesive resin into the water, and cutting the adhesive resin extruded into the water to form adhesive resin pellets. Polyolefin fine particles used for the antiblocking agent have an average particle diameter of 1 ?m or more and less than 18 ?m, and the adhesive resin has an adhesive force of less than 15.00 N/25 mm.

Abstract: The present invention provides an adhesive tape or sheet with a separator comprising an adhesive tape or sheet comprising a support layer and an adhesive layer laminated on the upper side of the support layer; and a separator located on the upper side of the adhesive layer, wherein the separator has a three-layer structure in which a first A layer, a B layer, and a second A layer are laminated in this order from the lower side; the first A layer and the second A layer are formed of the same type of unstretched polyolefin film, and the B layer is formed of a biaxially stretched polyolefin film; and the thickness of the first A layer is 70% or more and 130% or less of the thickness of the second A layer.

Abstract: [PROBLEMS TO BE SOLVED] To provide a method of advantageously improving a transdermal permeation amount of a steroid drug to diseased portions when treating ophthalmic diseases such as chalazion, blepharitis, allergic conjunctivitis, vernal keratoconjunctivitis, and meibomian gland dysfunction. [SOLUTION] To provide the transdermal drug delivery system for administering a drug via the eyelid skins that have been treated with a microneedle array, featured in that the drug is a water-soluble steroid, and the transdermal drug delivery system is a water-containing base adhesive skin patch.

Abstract: To provide a packaging for a rivastigmine-containing adhesive patch having excellent temporal stability of rivastigmine, an adhesive patch product including the adhesive patch and a packaging bag, and a method for manufacturing the same. An adhesive patch product including a packaging bag formed from a laminate of at least three layers including an ethylene-vinyl alcohol copolymer film and a rivastigmine-containing adhesive patch housed in the packaging bag and having a residual oxygen concentration of 10% by volume or less in the packaging bag, and a method for manufacturing the same are provided. In addition, a packaging for a rivastigmine-containing adhesive patch formed from a laminate including an ethylene-vinyl alcohol copolymer film and having a residual oxygen concentration of 10% by volume or less therein is provided.

Abstract: A binding apparatus includes a pressure bonding mechanism in which pressure is applied by a pair of pressure bonding plates to a joining portion of a binding tape, which is an adhesive tape, to fasten it together by gripping and squeezing a pair of levers to rotate a pair of arms around a fulcrum. Thereby, any mixing of metal staples into an object to be bound as in a conventional binding apparatus is eliminated, and thus the quality of the object to be bound can be ensured. Further, the need for a strong grip strength like that when ejecting a staple is eliminated, and thus the burden on an operator can be reduced.

Abstract: To provide a packaging body for a patch exhibiting excellent temporal stability of a drug, a patch product equipped with the patch and a packaging bag, and a method of manufacturing the patch product. A patch product equipped with a packaging bag formed of a laminate composed of at least three or more layers including a cyclic polyolefin film and a lidocaine- or rivastigmine-containing patch housed in the packaging bag, a method of the patch product, and a packaging body for a patch formed of a laminate including a cyclic polyolefin film.

Abstract: A chip-resistant film includes a composite substrate having an ionomer layer and a polyolefin-based polymer layer, with a strength at upper yield point of 10 to 40 N/10 mm, wherein a pressure-sensitive adhesive, which may be an acrylic pressure-sensitive adhesive, is placed over the polyolefin-based polymer layer. The chip-resistant film may also include an intermediate adhesive layer positioned between the ionomer layer and the polyolefin-based polymer layer. The chip resistance of an object to which the chip-resistant film has been applied is improved.

Abstract: A device for interstitial fluid extraction, having a base material formed from a synthetic resin film, a pressure sensitive adhesive layer, a hydrogel layer formed from at least one hydrophilic polymer selected from the group consisting of polyvinyl alcohol and polyvinyl pyrrolidone, and a release layer, wherein the hydrogel layer has an area of a size that the pressure sensitive adhesive layer is exposed from around the hydrogel layer, does substantially not contain a sodium ion and causes no water separation.

Abstract: A transdermal patch for the treatment of Alzheimer's disease includes: a backing, a rivastigmine-containing layer, a pressure-sensitive adhesive layer, and a release liner. In the transdermal patch, the rivastigmine-containing layer contains rivastigmine and an alkyl(meth)acrylate resin, the pressure-sensitive adhesive layer is composed of an acrylic pressure-sensitive adhesive containing a (meth)acrylic acid ester having a hydroxyl group, and neither the rivastigmine-containing layer nor the pressure-sensitive adhesive layer contains an anti-oxidizing agent.

Abstract: An anti-chipping sheet includes at least a substrate layer and a pressure-sensitive adhesive layer, wherein the substrate layer comprises laminated multiple ionomer layers, each of which comprises an ionomer produced by neutralizing carboxyl groups of an ethylene-unsaturated carboxylic acid copolymer with metal ions, one of the multiple ionomer layers is a high-rigidity ionomer layer, located at the outermost layer and not in contact with the pressure-sensitive adhesive layer of the substrate layer, and having stiffness of 200 N/mm2 or higher, and another one of the multiple ionomer layers is a low-rigidity ionomer layer, located toward the pressure-sensitive adhesive layer in relation to the outermost layer, and having stiffness of lower than 200 N/mm2.

Abstract: A transdermal patch for the treatment of Alzheimer's disease includes: a backing, a rivastigmine-containing layer, a pressure-sensitive adhesive layer, and a release liner. In the transdermal patch, the rivastigmine-containing layer contains rivastigmine and an alkyl (meth)acrylate resin, the pressure-sensitive adhesive layer is composed of an acrylic pressure-sensitive adhesive containing a (meth)acrylic acid ester having a hydroxy group, and neither the rivastigmine-containing layer nor the pressure-sensitive adhesive layer contains an anti-oxidizing agent.

Abstract: A device for interstitial fluid extraction, having a base material formed from a synthetic resin film, a pressure sensitive adhesive layer, a hydrogel layer formed from at least one hydrophilic polymer selected from the group consisting of polyvinyl alcohol and polyvinyl pyrrolidone, and a release layer, wherein the hydrogel layer has an area of a size that the pressure sensitive adhesive layer is exposed from around the hydrogel layer, does substantially not contain a sodium ion and causes no water separation.

Abstract: A transdermal patch for the treatment of Alzheimer's disease includes: a backing, a rivastigmine-containing layer, a pressure-sensitive adhesive layer, and a release liner. In the transdermal patch, the rivastigmine-containing layer contains rivastigmine and an alkyl (meth)acrylate resin, the pressure-sensitive adhesive layer is composed of an acrylic pressure-sensitive adhesive containing a (meth)acrylic acid ester having a hydroxy group, and neither the rivastigmine-containing layer nor the pressure-sensitive adhesive layer contains an anti-oxidizing agent.

Abstract: An adhesive transfer device can reliably transfer by simple operation an adhesive onto a transfer target surface by either of spot-like transfer and linear transfer that are alternately selected. The adhesive transfer device has a supply reel (20) around which a transfer tape (1) having a backing material (2) provided with an adhesive (3) on one surface thereof is wound, a take-up reel (30) for taking up the transfer tape, and a transfer head (40) for transferring the adhesive onto the transfer target surface. The transfer head is pivotally supported at one end thereof and includes a first transfer section (45a) formed at a free end portion thereof and having a circular arc-shaped contact surface for mutual contact with the transfer target surface, a second transfer section (45b) having a flat transfer surface (45c) between the first transfer section and a pivot portion of the transfer head, and a spring member (46) for urging the free end portion of the transfer head toward the transfer target surface.