Abstract: The present invention is to provide a tissue slice selection method and an embedded block-preparing cassette which are capable of suppressing occurrence of errors in inspection results. The present invention makes it possible to suppress the occurrence of errors in inspection results by including: an embedded block-preparing process of preparing an embedded block by embedding both a biological tissue fragment and a standard substance in the same embedding agent; an embedded tissue slice preparing step of slicing the embedded block to prepare a sheet-like embedded tissue slice having a tissue slice and standard substance slices appearing on a surface thereof; and a tissue slice selecting step of selecting the tissue slice to be inspected, based on a light signal from the standard substance slice.

Abstract: The present invention relates to a combination product for detecting a target marker simply and with high sensitivity. More specifically, the present invention relates to a combination product for detecting a target marker in a biological sample in combination with a target marker binding molecule which is capable of binding specifically to the target marker in the biological sample, the combination comprising, at least: (a) a first binding agent comprising a first binding molecule which is capable of directly or indirectly binding specifically to the target marker binding molecule, and a labeling substance; (b) a linker molecule which is capable of binding specifically to the first binding agent; and (c) a second binding agent which is capable of binding specifically to the linker molecule, and comprises a second binding molecule and a labeling substance.

Abstract: An automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges an occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples in the first region, suspends a start of a treatment for the samples in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples in the first region when the horizontal direction movement unit is not occupied.

Abstract: The present invention is to provide a tissue slice selection method and an embedded block-preparing cassette which are capable of suppressing occurrence of errors in inspection results. The present invention makes it possible to suppress the occurrence of errors in inspection results by including: an embedded block-preparing process of preparing an embedded block by embedding both a biological tissue fragment and a standard substance in the same embedding agent; an embedded tissue slice preparing step of slicing the embedded block to prepare a sheet-like embedded tissue slice having a tissue slice and standard substance slices appearing on a surface thereof; and a tissue slice selecting step of selecting the tissue slice to be inspected, based on a light signal from the standard substance slice.

Abstract: The present invention relates to an agent for effectively suppressing an increase in a blood acetaldehyde level. More specifically, the present invention relates to an alcohol metabolism promoter comprising glycogen obtained from a Veneroida bivalve.

Abstract: The present invention relates to a combination product for detecting a target marker simply and with high sensitivity. More specifically, the present invention relates to a combination product for detecting a target marker in a biological sample in combination with a target marker binding molecule which is capable of binding specifically to the target marker in the biological sample, the combination comprising, at least: (a) a first binding agent comprising a first binding molecule which is capable of directly or indirectly binding specifically to the target marker binding molecule, and a labeling substance; (b) a linker molecule which is capable of binding specifically to the first binding agent; and (c) a second binding agent which is capable of binding specifically to the linker molecule, and comprises a second binding molecule and a labeling substance.

Abstract: The present invention relates to a combination product for detecting a target marker simply and with high sensitivity. More specifically, the present invention relates to a combination product for detecting a target marker in a biological sample in combination with a target marker binding molecule which is capable of binding specifically to the target marker in the biological sample, the combination comprising, at least: (a) a first binding agent comprising a first binding molecule which is capable of directly or indirectly binding specifically to the target marker binding molecule, and a labeling substance; (b) a linker molecule which is capable of binding specifically to the first binding agent; and (c) a second binding agent which is capable of binding specifically to the linker molecule, and comprises a second binding molecule and a labeling substance.

Abstract: An automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges an occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples in the first region, suspends a start of a treatment for the samples in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples in the first region when the horizontal direction movement unit is not occupied.

Abstract: An automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges an occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples in the first region, suspends a start of a treatment for the samples in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples in the first region when the horizontal direction movement unit is not occupied.

Abstract: The present invention relates to an agent for effectively suppressing an increase in a blood acetaldehyde level. More specifically, the present invention relates to an alcohol metabolism promoter comprising glycogen obtained from a Veneroida bivalve.

Abstract: Provided are an automatic tissue staining device and an automatic tissue staining method capable of advancing treatments according to precise treatment times without a hitch. The automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set.

Abstract: A liquid filling aid that is placed on a plate-shaped member and defines a reaction chamber to be filled with a liquid, the aid includes a main body, a storage section that is formed in the main body and stores the liquid, a reaction section that is a recess formed at a bottom of the main body, a communication aperture for fluid communication between the storage section and the reaction section, and an air vent for communication between the reaction section and outside air, wherein the reaction section and an upper surface of the plate-shaped member define the reaction chamber and a liquid filling method including a step of placing the liquid filling aid on the plate-shaped member, and a step of discharging the liquid in an amount equal to or larger than the volume of the reaction chamber for supply to the storage section.

Abstract: Disclosed are a pretreatment solution for immunohistochemical staining, which elutes a paraffin-containing embedding medium from a glass slide with a tissue specimen embedded in the medium, and retrieves antigenicity of the tissue specimen, and which is usable three or more times, and a pretreatment solution concentrate for immunohistochemical staining which allows ready preparation of the pretreatment solution and a method of immunohistochemical staining using the same. The pretreatment solution contains an antigen retrieving agent, particular nonionic surfactants, and cyclodextrin or a derivative thereof, with the balance being not less than 80 mass % of water. The content of the antigen retrieval agent is such that the pH of the pretreatment solution is in a predetermined range, and the content of cyclodextrin or a derivative thereof is a particular amount.

Abstract: The present invention relates to a combination product for detecting a target marker simply and with high sensitivity. More specifically, the present invention relates to a combination product for detecting a target marker in a biological sample in combination with a target marker binding molecule which is capable of binding specifically to the target marker in the biological sample, the combination comprising, at least: (a) a first binding agent comprising a first binding molecule which is capable of directly or indirectly binding specifically to the target marker binding molecule, and a labeling substance; (b) a linker molecule which is capable of binding specifically to the first binding agent; and (c) a second binding agent which is capable of binding specifically to the linker molecule, and comprises a second binding molecule and a labeling substance.

Abstract: This receptacle containing a test reagent is provided with: an information display part, situated on the upper surface, for display of information relating to a test reagent contained in the receptacle body; and a lid part connected to the upper surface and rotatable with respect to the receptacle body, for opening and closing a passage hole. The lid part closes off the passage hole such that the information display part is visible.

Abstract: Provided is a DAB-containing substrate kit that is capable of enhancing specific staining intensity and reducing precipitation due to DAB aggregation in DAB-containing substrate solution and nonspecific staining, such as background staining, in chromogenic reaction using a peroxidase-labeled antibody, by the use of chromogenic reaction solution containing DAB and its sensitizer imidazole. The kit includes chromophore-containing solution (A) containing a peroxidase chromophore DAB and water; and chromogenic reagent (B) containing: at least one chelating agent selected from the group consisting of EDTA-2Na, EDTA-2NH4, GEDTA, and NTA; POE and/or POP alkyl ether nonionic surfactant; imidazole; hydrogen peroxide; and water. The kit is in a system of two- or more components with at least the chromophore-containing solution (A) and the chromogenic reagent (B) being separately stored.

Abstract: A liquid filling aid that is placed on a plate-shaped member and defines a reaction chamber to be filled with a liquid, the aid includes a main body, a storage section that is formed in the main body and stores the liquid, a reaction section that is a recess formed at a bottom of the main body, a communication aperture for fluid communication between the storage section and the reaction section, and an air vent for communication between the reaction section and outside air, wherein the reaction section and an upper surface of the plate-shaped member define the reaction chamber and a liquid filling method including a step of placing the liquid filling aid on the plate-shaped member, and a step of discharging the liquid in an amount equal to or larger than the volume of the reaction chamber for supply to the storage section.

Abstract: This invention relates to an extract obtained from a plant of the genus Odontoglossum of the family Orchidaceae, or from a plant derived from a hybrid plant of the genus Odontoglossum and the genus Cochlioda, to a method for preparing the extract, and to an external agent for skin comprising the extract.

Abstract: Provided is a thermostat with reduced temperature difference within the tank when a solution is being heat-treated. Stirring guides (114) for guiding a water-flow generated by a stirring bar (113) to both ends of a tank (106) in the longitudinal direction are disposed on the bottom of the tank (106). Thus, the water-flow generated by the stirring bar (113) is efficiently guided to both ends of the tank (106) in the longitudinal direction while keeping its momentum, and therefore a circulating water-flow for homogenizing the temperature of the water within the tank (106) can be effectively generated.

Abstract: This invention provides a skin-whitening agent, a tyrosinase activity inhibitor, and melanin production inhibitor comprising, as an active ingredient, a compound exhibiting excellent solubility in various solvents. Such skin-whitening agent, tyrosinase activity inhibitor, and melanin production inhibitor comprise 3-hydroxy-2-pyrone.