Abstract: An object of the present application is to provide an orally-disintegrating tablet having excellent tablet hardness and disintegrability, and including a disintegrative particulate composition. This invention relates to a disintegrative particulate composition comprising the four components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component other than the acid-type carboxymethylcellulose, an excipient of a sugar or sugar alcohol, and crystalline cellulose; and to an orally-disintegrating tablet, including the disintegrative particulate composition and a medicinal ingredient.
Type:
Grant
Filed:
September 13, 2013
Date of Patent:
May 21, 2019
Assignees:
DAICEL CORPORATION, NICHIRIN CHEMICAL INDUSTRIES, LTD.
Abstract: A process for the preparation of a powdery calcium cellulose glycolate which comprises reacting cellulose glycolic acid in wet form with a calcium reagent, drying and pulverizing the resultant, wherein the calcium reagent is calcium hydroxide or a combination of calcium hydroxide and calcium carbonate.
Type:
Grant
Filed:
August 23, 1984
Date of Patent:
April 2, 1985
Assignees:
Daicel Chemical Industries Ltd., Nichirin Chemical Industries Ltd.