Patents Assigned to Niconovum AB
  • Patent number: 8833378
    Abstract: A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a suitably loaded combination with a mean particle size that is suitable for use e.g. in snuff compositions packed in pouches of gauze or other materials with opening. The invention further relates to the use of such a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: September 16, 2014
    Assignee: Niconovum AB
    Inventors: Anders Axelsson, Arne Kristensen
  • Publication number: 20140234392
    Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose, The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine-containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: Niconovum AB
    Inventors: Henri Hansson, Arne Kristensen
  • Patent number: 8741348
    Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose. The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: June 3, 2014
    Assignee: Niconovum AB
    Inventors: Henri Hansson, Arne Kristensen
  • Publication number: 20130160782
    Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.
    Type: Application
    Filed: November 30, 2012
    Publication date: June 27, 2013
    Applicant: NICONOVUM AB
    Inventors: NICONOVUM AB, Marianne Kristensen
  • Publication number: 20110214681
    Abstract: A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a suitably loaded combination with a mean particle size that is suitable for use e.g. in snuff compositions packed in pouches of gauze or other materials with opening. The invention further relates to the use of such a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.
    Type: Application
    Filed: September 17, 2009
    Publication date: September 8, 2011
    Applicant: NicoNovum AB
    Inventors: Anders Axelsson, Arne Kristensen
  • Patent number: 7900637
    Abstract: The present invention relates to an aerosol spray device (10, 20, 30, 40) for administration of a substance, specifically a substance having a disagreeable taste, such as nicotine, to the oral cavity of a subject; to an actuator (16, 26, 36, 46) included in said spray device and to methods for delivering the substance.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: March 8, 2011
    Assignee: Niconovum AB
    Inventors: Karl-Olov Fagerstrom, Henri Hansson
  • Publication number: 20100061940
    Abstract: Use of a nicotine-cellulose combination and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine.
    Type: Application
    Filed: March 16, 2007
    Publication date: March 11, 2010
    Applicant: NicoNovum AB
    Inventors: Anders Axelsson, Henri Hansson, Arne Kristensen
  • Publication number: 20100004294
    Abstract: Compositions comprising nicotine, which compositions provide a rapid release of nicotine. Nicotine is present in the form of a nicotine-cellulose combination. The compositions are designed for administration to the oral cavity where the nicotine is rapidly released from the composition and available for absorption through the oral mucosa. The compositions are lozenges and have excellent storage stability.
    Type: Application
    Filed: September 16, 2007
    Publication date: January 7, 2010
    Applicant: NicoNovum AB
    Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
  • Publication number: 20090293895
    Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 3, 2009
    Applicant: NicoNovum AB
    Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
  • Patent number: D608218
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: January 19, 2010
    Assignee: Niconovum AB
    Inventors: Timothy James Llewellyn, Dominic Peter Hale
  • Patent number: D634204
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: March 15, 2011
    Assignee: Niconovum AB
    Inventors: Timothy James Llewellyn, Dominic Peter Hale