Abstract: A method for the promotion or acceleration of wound healing by a treatment with minoxidil is disclosed. The minoxidial can be administered by topical application, oral administration, injection or any combination thereof. Treatment with minoxidil is effective for promoting the migration of epithelial cells in a wound or in tissues such as cornea and the like. Methods for identifying binding sites for minoxidil in cells based on their affinity for the compound in attachment or chemotactic assays are described.
Type:
Grant
Filed:
December 7, 1988
Date of Patent:
March 27, 1990
Assignees:
The Upjohn Company, NIDR NIH
Inventors:
Anthony C. Sank, George R. Martin, Steven R. Ledbetter