Abstract: The disclosed subject matter related to methods and apparatus for determining brain swelling in a patient as well as predicting an increase in intracranial pressure in the patient. The apparatus can include a transducer such as an ultrasound transducer communicatively connected to a controller via wires or via wireless communications device(s). A monitor and/or alarm device can be provided to notify a practitioner when the controller has determined brain swelling is occurring and/or when an imminent increase in intracranial pressure is likely to occur.
Abstract: A protection circuit module includes an insulating substrate, a first surge withstand chip resistor mounted on a pair of first pads formed on one surface of the insulating substrate, a second surge withstand chip resistor mounted on a pair of second pads formed on the other surface of the insulating substrate, and arranged at a position on the other surface of the insulating substrate overlapping the first surge withstand chip resistor in a plan view, a first wiring coupled to one first pad, a second wiring coupled to one second pad, a third wiring coupling the other first pad and the other second pad to the same potential, and a shield wiring provided on an inner layer of the insulating substrate and arranged in a region in which at least the one first pad and the one second pad oppose each other.
December 7, 2018
Date of Patent:
October 6, 2020
SHINKO ELECTRIC INDUSTRIES CO., LTD., NIHON KOHDEN CORPORATION
Abstract: A headwear for electroencephalography is provided. The headwear includes a first arm to be attached to an area extending from a forehead or an occiput of a subject to a top of a head of the subject and configured to hold a first electroencephalogram electrode, a second arm connected to the first arm to be attached to a lateral side of the head of the subject and configured to hold a second electroencephalogram electrode, a third arm connected to the first arm to be attached to another lateral side of the head of the subject and configured to hold a third electroencephalogram electrode, a stretchable support member connectable to the first to third arms to cover at least a portion of the head in a direction toward the first arm, and at least one adjusting mechanism to adjust tightness of the first to third arms to the head.
Abstract: A venous pressure measurement apparatus includes a pressure controller configured to change a pressure applied from a cuff to a portion of a body where a vein and an artery exist and to which the cuff is attached, a pulse wave detector configured to detect pulse waves from a pressure the cuff receives from the portion of the body, and a venous pressure calculating section configured to calculate a venous pressure based on the applied pressure and the pulse waves detected by the pulse wave detector during a period in which the applied pressure is changed. The pressure controller is configured to execute a plurality of measurement steps, the applied pressure being increased or reduced from an initial value in each of the measurement steps.
Abstract: A pulse wave analyzing apparatus comprises an acquiring section (11) which acquires a pulse wave that is non-invasively measured, and an analyzer (12) which calculates data on the frequency axis by using the pulse wave, and which obtains the index value of the respiratory-induced variation based on the calculated data on the frequency axis.
December 3, 2015
Date of Patent:
October 6, 2020
HIROSHIMA UNIVERSITY, NIHON KOHDEN CORPORATION
Abstract: The presently disclosed subject matter is to provide a hepatocyte structure, particularly, a hepatocyte structure that mimics nonalcoholic steatohepatitis (NASH). A hepatocyte construct including an aggregate containing hepatocytes and adherent cells that are non-hepatocytes, and wherein the hepatocytes include ballooned hepatocytes is provided. Further, a method for producing a hepatocyte construct, comprising: (i) forming an aggregate by aggregating a cell group comprising hepatocytes and adherent cells that are non-hepatocytes; and (ii) culturing the aggregate is provided.
July 3, 2019
September 17, 2020
NIHON KOHDEN CORPORATION, TOKYO WOMEN'S MEDICAL UNIVERSITY
Abstract: An automatic measurement point correction method includes acquiring vital signs information waveform data indicating a vital signs information waveform having a plurality of waveforms which periodically appear on a time axis, determining a plurality of measurement points for measuring a predetermined measurement item of each waveform included in the vital signs information waveform, causing the vital signs information waveform and measurement point displayers to be displayed on a displaying section, correcting a first measurement point for measuring the predetermined measurement item of a first waveform of the plurality of waveforms, as a first correction, recording the corrected first measurement point as a reference measurement point, extracting a waveform which is analogous to the first waveform, from the plurality of waveforms, and automatically correcting a measurement point for measuring the predetermined measurement item of the extracted waveform, as a second correction.
Abstract: A pulse photometry probe includes a holding member that includes a contact face which is to be in contact with living tissue of a patient, an emitter that is placed in the holding member, a detector that is placed in the holding member and detects light emitted from the emitter, and, a spacer that is disposed between the contact face and the emitter and has an opening, wherein an air layer defined by the opening is disposed between an emitting face of the emitter and the contact face.
Abstract: A device for measuring a tension of a cell structure containing muscle cells includes a first and a second gel adaptor holder. The first gel adaptor holder includes a frame member and a first gel holding portion which is disposed protrudingly from a part of an inner surface of the frame member for fixing one end of a gel. The second gel adaptor holder includes a second gel holding portion that fixes another end of the gel, and connecting members connected with the second gel holding portion. A kit including the device, a substrate and a gel forming cover. The substrate includes a pair of gel shaping convex parts fitted along the inner surface of the frame member. The gel forming cover includes a surface parallel to a gel contacting surface of the substrate, in order to form an upper surface of the gel.
Abstract: A transmission device can be carried by the subject. A biological signal recording device can perform wireless communication with the transmission device. A transmitter transmits biological signal data corresponding to a biological signal of a subject. A storage stores the biological signal data. A receiver receives the biological signal data. A recorder records the biological signal data received by the receiver. A detector detects a missing portion in the biological signal data recorded by the recorder or a receipt of the biological signal data by the receiver. A notifier notifies the missing portion or transmits an acknowledgment of the receipt to the transmission device. A complementary transmitter retrieves biological signal data corresponding to the notified missing portion from the storage or identifies unreceived biological signal data and retrieves the identified biological signal data, and transmits the retrieved biological signal data.
Abstract: A vital information monitor (1) includes a vital sign acquiring section (39) which acquires vital signs of a patient into whom a tracheal tube (14) connected to a respirator (13) is intubated, a producing section (31) which produces an extubation process display screen (72) on which determination items contained in an extubation process for removing the tracheal tube (14) from the patient are displayed, a displaying section (7) on which the vital signs acquired by the vital sign acquiring section and the extubation process display screen (72) are displayed, and a determining section (30) which determines whether the determination items satisfy predetermined conditions.
Abstract: A biological signal acquirer is attached to a subject and acquires a biological signal of the subject. A transmitter carried by the subject transmits the biological signal. A first communication port and a first camera are installed in a first location and connectable to a network. A second communication port and a second camera are installed in a second location and connectable to the network. A biological information acquiring device is connectable to the network and provided with a switcher. The switcher acquires, when communication establishment between the transmitter and the first communication port is detected, the biological signal through the first communication port as well as a first image taken by the first camera, and acquires, when communication establishment between the transmitter and the second communication port is detected, the biological signal through the second communication port as well as a second image taken by the second camera.
Abstract: An electrode package includes an electrode pad to be attached to a subject, the electrode pad having a gel layer, a lead wire having one end electrically coupled to the gel layer, and a packaging cover having an opening portion, the opening portion being sealed such that the electrode pad and a part of the lead wire are housed inside the packaging cover. A sealing width in at least a part of a section where the packaging cover is sealed together with the lead wire is narrower than a sealing width in a section where only the packaging cover is sealed. A sealing apparatus is configured to seal the packaging cover.
Abstract: Disclosed is a method for detecting lipid bilayer membrane particles or fragments thereof, having predetermined molecules existing on surfaces thereof, in a biological sample collected from a subject, the method comprising: adding to the biological sample a dye that stains a lipid bilayer membrane; adding a substance that specifically binds to the predetermined molecules; trapping the substance bound to the predetermined membrane molecules and separating unbound components; and detecting the separated stained lipid bilayer membrane particles or fragments thereof by measurement of the dye emission spectrum. The specific binding substance is conjugated to a magnetic bead or binds to a magnetic bead, the trapping and separating steps are performed magnetically, and the particle size of the magnetic bead is equal to or less than the minimum detection sensitivity of the measurement system.
April 13, 2018
Date of Patent:
August 4, 2020
NIHON KOHDEN CORPORATION
Yutaka Nagai, Masashi Takao, Masami Ito
Abstract: A medical photometer includes a processor and a memory that stores an instruction readable by a computer. When the instruction is executed by the processor, the medical photometer acquires a first light attenuation of a first light beam that is transmitted through or reflected from a tissue of a living body, and that has a first wavelength, based on a first intensity signal corresponding to an intensity of the first light beam, acquires a second light attenuation of a second light beam that is transmitted through or reflected from the tissue, and that has a second wavelength, based on a second intensity signal corresponding to an intensity of the second light beam, calculates a tissue thickness based on a ratio of the first light attenuation and the second light attenuation, and detects an artifact of the living body based on a temporal variation of the tissue thickness.
Abstract: A medical photometer includes a processor and a memory that stores an instruction readable by a computer. When the instruction is executed by the processor, the medical photometer acquires an intensity of one of a first intensity signal and a second intensity signal, the first intensity signal corresponding to an intensity of a first light beam that has a first wavelength and that is transmitted through or reflected from a tissue of a living body, and a second intensity signal corresponding to an intensity of a second light beam that has a second wavelength and that is transmitted through or reflected from the tissue of the living body acquires an intensity ratio of the first intensity signal and the second intensity signal, and detects an artifact of the living body based on the acquired intensity and the acquired intensity ratio.
Abstract: A myocardial excitation complementation/visualization apparatus includes an acquiring section that acquires intracardiac electrocardiograms of a subject, the intracardiac electrocardiograms being recorded by a recording unit having a plurality of electrodes, a processing section that performs a computation for completing and visualizing a state of excitation in a myocardium of the subject based on the intracardiac electrocardiograms, and a displaying section that displays the state of excitation in the myocardium of the subject based on an output of the processing section. The processing section includes a first generating section, a correcting section, a second generating section, and a third generating section. The displaying section displays a change of the state of excitation in the myocardium of the subject based on the visualized data.
March 25, 2020
July 16, 2020
SHIGA UNIVERSITY OF MEDICAL SCIENCE, NIHON KOHDEN CORPORATION, Takeshi TSUCHIYA, NATIONAL CERERAL AND CARDIOVASCULAR CENTER
Abstract: A remote maintenance system includes: a medical device which includes: a first power source; a first power source controller which controls an ON/OFF operation of the first power source; a checker which checks a check item; and a first communicator which transmits first information including a result of a check by the checker; and a relay unit which includes: a second power source; a second power source controller which automatically controls an ON/OFF operation of the second power source; and a second communicator which communicates with the first communicator and which receives the first information from the first communicator.
Abstract: A pulse photometer includes a light emitter, a light detector, a first signal separator that separates a first signal component and a first noise component, a second signal separator that separates a second signal component and a second noise component, a first determining section, a second determining section, and a concentration calculating section that calculates a concentration of a light absorption material in blood of the subject based on a fundamental frequency of the first signal component or a fundamental frequency of the second signal component.
Abstract: A non-invasive venous pressure measurement apparatus is provided, including: a first cuff attached to a portion including a vein and an artery in a living body; a pressure control unit that changes a first applied pressure applied by the cuff to the portion; a pulse wave detection unit that detects a pulse wave from a pressure received by the cuff from the portion; another pulse wave detection unit that detects another pulse wave including at least an arterial pulse wave in another portion of the living body; an analyzing unit that analyzes a correlation between the two pulse waves, which are changed as the applied pressure is changed by the pressure control unit changes; and a venous pressure calculation unit that calculates a venous pressure based on the applied pressure and a result of analysis by the analyzing unit.