Patents Assigned to Nihon Kohden Corporation
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Patent number: 10737089Abstract: An electrode package includes an electrode pad to be attached to a subject, the electrode pad having a gel layer, a lead wire having one end electrically coupled to the gel layer, and a packaging cover having an opening portion, the opening portion being sealed such that the electrode pad and a part of the lead wire are housed inside the packaging cover. A sealing width in at least a part of a section where the packaging cover is sealed together with the lead wire is narrower than a sealing width in a section where only the packaging cover is sealed. A sealing apparatus is configured to seal the packaging cover.Type: GrantFiled: August 26, 2016Date of Patent: August 11, 2020Assignee: Nihon Kohden CorporationInventor: Michio Kanemoto
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Patent number: 10732181Abstract: Disclosed is a method for detecting lipid bilayer membrane particles or fragments thereof, having predetermined molecules existing on surfaces thereof, in a biological sample collected from a subject, the method comprising: adding to the biological sample a dye that stains a lipid bilayer membrane; adding a substance that specifically binds to the predetermined molecules; trapping the substance bound to the predetermined membrane molecules and separating unbound components; and detecting the separated stained lipid bilayer membrane particles or fragments thereof by measurement of the dye emission spectrum. The specific binding substance is conjugated to a magnetic bead or binds to a magnetic bead, the trapping and separating steps are performed magnetically, and the particle size of the magnetic bead is equal to or less than the minimum detection sensitivity of the measurement system.Type: GrantFiled: April 13, 2018Date of Patent: August 4, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Yutaka Nagai, Masashi Takao, Masami Ito
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Patent number: 10722153Abstract: A medical photometer includes a processor and a memory that stores an instruction readable by a computer. When the instruction is executed by the processor, the medical photometer acquires an intensity of one of a first intensity signal and a second intensity signal, the first intensity signal corresponding to an intensity of a first light beam that has a first wavelength and that is transmitted through or reflected from a tissue of a living body, and a second intensity signal corresponding to an intensity of a second light beam that has a second wavelength and that is transmitted through or reflected from the tissue of the living body acquires an intensity ratio of the first intensity signal and the second intensity signal, and detects an artifact of the living body based on the acquired intensity and the acquired intensity ratio.Type: GrantFiled: October 25, 2017Date of Patent: July 28, 2020Assignee: Nihon Kohden CorporationInventors: Yoshinori Ueda, Teiji Ukawa, Kazumasa Ito, Hideki Fujisaki
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Patent number: 10722154Abstract: A medical photometer includes a processor and a memory that stores an instruction readable by a computer. When the instruction is executed by the processor, the medical photometer acquires a first light attenuation of a first light beam that is transmitted through or reflected from a tissue of a living body, and that has a first wavelength, based on a first intensity signal corresponding to an intensity of the first light beam, acquires a second light attenuation of a second light beam that is transmitted through or reflected from the tissue, and that has a second wavelength, based on a second intensity signal corresponding to an intensity of the second light beam, calculates a tissue thickness based on a ratio of the first light attenuation and the second light attenuation, and detects an artifact of the living body based on a temporal variation of the tissue thickness.Type: GrantFiled: October 25, 2017Date of Patent: July 28, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Yoshinori Ueda, Teiji Ukawa, Kazumasa Ito, Hideki Fujisaki
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Publication number: 20200221964Abstract: A myocardial excitation complementation/visualization apparatus includes an acquiring section that acquires intracardiac electrocardiograms of a subject, the intracardiac electrocardiograms being recorded by a recording unit having a plurality of electrodes, a processing section that performs a computation for completing and visualizing a state of excitation in a myocardium of the subject based on the intracardiac electrocardiograms, and a displaying section that displays the state of excitation in the myocardium of the subject based on an output of the processing section. The processing section includes a first generating section, a correcting section, a second generating section, and a third generating section. The displaying section displays a change of the state of excitation in the myocardium of the subject based on the visualized data.Type: ApplicationFiled: March 25, 2020Publication date: July 16, 2020Applicants: SHIGA UNIVERSITY OF MEDICAL SCIENCE, NIHON KOHDEN CORPORATION, Takeshi TSUCHIYA, NATIONAL CERERAL AND CARDIOVASCULAR CENTERInventors: Takashi ASHIHARA, Koji Takizawa, Tatsuo Nishihara, Nobuhiro Suzuki, Yuuho Iwanaga, Akio Ota, Takeshi Tsuchiya, Kazuo Nakazawa, Shin Inada
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Patent number: 10708074Abstract: A remote maintenance system includes: a medical device which includes: a first power source; a first power source controller which controls an ON/OFF operation of the first power source; a checker which checks a check item; and a first communicator which transmits first information including a result of a check by the checker; and a relay unit which includes: a second power source; a second power source controller which automatically controls an ON/OFF operation of the second power source; and a second communicator which communicates with the first communicator and which receives the first information from the first communicator.Type: GrantFiled: February 25, 2011Date of Patent: July 7, 2020Assignee: Nihon Kohden CorporationInventors: Tsutomu Wakabayashi, Shinji Tezuka, Tadashi Nakayama
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Patent number: 10702196Abstract: A pulse photometer includes a light emitter, a light detector, a first signal separator that separates a first signal component and a first noise component, a second signal separator that separates a second signal component and a second noise component, a first determining section, a second determining section, and a concentration calculating section that calculates a concentration of a light absorption material in blood of the subject based on a fundamental frequency of the first signal component or a fundamental frequency of the second signal component.Type: GrantFiled: November 21, 2017Date of Patent: July 7, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Yoshinori Ueda, Teiji Ukawa, Kazumasa Ito, Hideki Fujisaki
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Publication number: 20200195724Abstract: A physiological information processing apparatus is to be communicatively connected to a plurality of physiological information sensors each of which is configured to acquire physiological information data of a subject being tested. The physiological information processing apparatus is configured to: receive first physiological information data from a first physiological information sensor of the plurality of physiological information sensors, in an xth first subframe (x: natural number) of a plurality of first subframes divided from an nth main frame (n: natural number); and receive the first physiological information data from the first physiological information sensor, in an xth second subframe of a plurality of second subframes divided from an mth main frame (m: natural number).Type: ApplicationFiled: December 4, 2019Publication date: June 18, 2020Applicant: NIHON KOHDEN CORPORATIONInventors: Hironori SUGAWARA, Yukio KOYAMA, Hiroshi Kubo
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Publication number: 20200178844Abstract: A condition change determination method and condition change determination apparatus that, when a medical person uses a method for determining a condition change of a patient, such as NEWS, can accurately determine the condition of the patient, and a program and computer readable medium that are to be used in the apparatus or the method are provided. A non-transitory computer readable medium including a program causes a computer to realize the functions of: acquiring at least one of apnea and hypopnea rates of a patient; acquiring vital signs information of the patient other than the apnea and hypopnea rates; and determining a condition change of the patient by a determination method for determining a condition change of a patient based on at least one of the apnea and hypopnea rates, and the vital signs information other than the apnea and hypopnea rates.Type: ApplicationFiled: December 5, 2019Publication date: June 11, 2020Applicant: NIHON KOHDEN CORPORATIONInventors: Takayuki SUGIYAMA, Akihiko YOSHIMURA, Kazuri HIGASHI
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Patent number: 10678531Abstract: A method includes: receiving, from at least one physiological information detecting sensor, flag information indicating whether an acceleration of the physiological information detecting sensor is higher than a threshold or not, and sensor identification information of the physiological information detecting sensor, wherein the flag information and the sensor identification information are associated with each other, and the physiological information detecting sensor stores first software; displaying the sensor identification information on a display; changing a visual aspect of the sensor identification information displayed on the display in accordance with the flag information; transmitting second software for updating a version of the first software to the physiological information detecting sensor indicated by the sensor identification information selected through a user input operation; and updating the version of the first software based on the second software.Type: GrantFiled: July 3, 2018Date of Patent: June 9, 2020Assignee: NIHON KOHDEN CORPORATIONInventor: Norihito Konno
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Publication number: 20200140807Abstract: The present invention provides a method for swiftly producing a layered cell sheet that is non-invasively obtained and is utilizable for transplantation, etc., the method including (1) a step of applying a centrifugal force to a first cell sheet on a temperature-responsive culture surface for a predetermined time in a temperature range from a lower critical solution temperature of the temperature-responsive culture surface to 45° C., (2) a step of further placing a second cell sheet on the first cell sheet, and (3) a step of applying a centrifugal force to the first cell sheet and the second cell sheet on the temperature-responsive culture surface for a predetermined time in the temperature range from the lower critical solution temperature to 45° C.; and also provides a layered cell sheet obtained by the method.Type: ApplicationFiled: June 28, 2018Publication date: May 7, 2020Applicants: NIHON KOHDEN CORPORATION, TOKYO WOMEN'S MEDICAL UNIVERSITYInventors: Yuki KAGAWA, Tatsuya SHIMIZU, Yuji HARAGUCHI, Hirotsugu KUBO
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Patent number: 10633709Abstract: An apparatus and a method for diagnosing a tumor are provided. A histogram generating section generates a histogram from a result of a measurement of fluorescence intensity of a suspension produced from a target sample. The histogram indicates a relation between the fluorescence intensity and the number of cells. A determination section detects an S phase fluorescence intensity range corresponding to S phase cells based on the fluorescence intensity corresponding to a peak of the number of cells in the histogram, detects an abnormal fluorescence intensity range corresponding to tumor cells, based on a change in the number of cells in the S phase fluorescence intensity range, and performs a diagnosis of a tumor in the target sample based on an index of the number of cells in a range defined by excluding the abnormal fluorescence intensity range from the S phase fluorescence intensity range.Type: GrantFiled: April 19, 2017Date of Patent: April 28, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Takahiro Shioyama, Akane Suzuki, Yoshitaka Amano
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Patent number: 10631790Abstract: A vital sign measurement apparatus including: an input operation section; a first measurement section capable of measuring first vital signs; first and second operating systems; a first arithmetic processing section that runs on the first operating system and that arithmetically processes the first vital signs on the basis of an input signal from the input operation section, thereby generating a first arithmetically processed signal; a second arithmetic processing section that runs on the second operating system, that is communicable with the first arithmetic processing section, and that generates a second arithmetically processed signal on the basis of the input signal from the input operation section by use of the first arithmetically processed signal transmitted from the first arithmetic processing section; and an output control section that can receive the first and second arithmetically processed signals and that outputs at least one of the received arithmetically processed signals.Type: GrantFiled: July 17, 2013Date of Patent: April 28, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Kenji Toyomura, Asao Igarashi
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Publication number: 20200123489Abstract: A sample storage apparatus includes: a lid member; a sample storage container; first and second fluid sucking sections; first and second fluid discharging sections; first to fourth flow paths; and a first fluid identification sensor. The first flow path is connected to the first fluid sucking section, the second flow path is connected to the second fluid sucking section, the third flow path is connected to the first fluid discharging section, and the fourth flow path is connected to the second fluid discharging section. The first fluid identification sensor for identifying a fluid is disposed in the first flow path.Type: ApplicationFiled: October 22, 2019Publication date: April 23, 2020Applicants: NIHON KOHDEN CORPORATION, OSAKA UNIVERSITYInventors: Hodaka MAKINO, Hirotsugu KUBO, Tetsuya OGAWA, Masahiro KINOOKA
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Patent number: 10624545Abstract: A biological information monitor includes: a measuring section which is configured to measure biological information having a periodically changing value; a sound outputting section which is configured to output a sound including a first sound and a second sound, in synchronization with a period of the biological information; and a sound controlling section which is configured to cause the second sound to be output in succession to the first sound, and which is configured to change the second sound in accordance with a value of the biological information.Type: GrantFiled: June 6, 2014Date of Patent: April 21, 2020Assignee: Nihon Kohden CorporationInventors: Toshiki Aoki, Shinji Yamamori, Masayuki Inoue, Katsuyuki Miyasaka, Kiyoyuki Miyasaka
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Patent number: 10624555Abstract: A myocardial excitation complementation/visualization apparatus includes an acquiring section that acquires intracardiac electrocardiograms of a subject, the intracardiac electrocardiograms being recorded by a recording unit having a plurality of electrodes, a processing section that performs a computation for completing and visualizing a state of excitation in a myocardium of the subject based on the intracardiac electrocardiograms, and a displaying section that displays the state of excitation in the myocardium of the subject based on an output of the processing section. The processing section includes a first generating section, a correcting section, a second generating section, and a third generating section. The displaying section displays a change of the state of excitation in the myocardium of the subject based on the visualized data.Type: GrantFiled: March 15, 2016Date of Patent: April 21, 2020Assignees: SHIGA UNIVERSITY OF MEDICAL SCIENCE, NIHON KOHDEN CORPORATION, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTERInventors: Takashi Ashihara, Koji Takizawa, Tatsuo Nishihara, Nobuhiro Suzuki, Yuuho Iwanaga, Akio Ota, Takeshi Tsuchiya, Kazuo Nakazawa, Shin Inada
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Publication number: 20200113436Abstract: A physiological information transmission method includes: by an information processing apparatus: acquiring sensor identification information of a physiological information detection sensor which is adapted to be attached to a living body, and living body identification information of the living body; and transmitting first association information associating the acquired sensor identification information and the acquired living body identification information, with each other; and by the physiological information detection sensor: receiving the first association information; determining whether or not the received first association information contains sensor identification information of the own sensor; and when the received first association information contains the sensor identification information of the own sensor, transmitting second association information associating the living body identification information in the received first association information, and physiological information which is detectType: ApplicationFiled: April 25, 2018Publication date: April 16, 2020Applicant: NIHON KOHDEN CORPORATIONInventors: Fumiyuki MATSUMURA, Norihito KONNO, Minori HOSOI
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Patent number: 10620702Abstract: An internal device of a brain-machine interface system includes: an electrode group including N electrodes, N being 2 or more; an amplification element group including N amplification elements; a communicator communicating with an external device; and a controller selectively executing one of: a normal operation mode in which electroencephalogram signals acquired through the N electrodes are supplied to the amplification element group in a manner that each of the N electrodes corresponds to a respective one of the N amplification elements, and N amplified electroencephalogram signals are transmitted; and a noise-reduction operation mode in which an electroencephalogram signal acquired through an M electrode of the electrode group is supplied to the amplification element group in a manner that each M electrode corresponds to respective plural ones of the amplification elements, and an M amplified electroencephalogram signal is transmitted, M being smaller than N.Type: GrantFiled: November 1, 2017Date of Patent: April 14, 2020Assignees: NIHON KOHDEN CORPORATION, OSAKA UNIVERSITY, NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGYInventors: Kaoru Imajo, Katsuyoshi Suzuki, Masayuki Hirata, Seiji Kameda, Takafumi Suzuki, Hiroshi Ando
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Publication number: 20200100689Abstract: A venous pressure measurement apparatus includes: a pressure controller that causes an internal pressure of a cuff to he attached to a subject, to change; a pressure detector that detects the internal pressure of the cuff; and a processor that causes the pressure controller to change the internal pressure of the cuff, acquires a statistical value relating to a distribution of amplitudes of a plurality of pressure changes corresponding to pressure vibration that occurs in the cuff, and that is detected by the pressure detector, and estimates a venous pressure of the subject based on a change of the statistical value due to the change of the internal pressure of the cuff.Type: ApplicationFiled: September 27, 2019Publication date: April 2, 2020Applicant: NIHON KOHDEN CORPORATIONInventors: Naoki KOBAYASHI, Haruka MORIMOTO
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Patent number: RE48076Abstract: A non-invasive venous pressure measurement apparatus is provided, including: a first cuff attached to a portion including a vein and an artery in a living body; a pressure control unit that changes a first applied pressure applied by the cuff to the portion; a pulse wave detection unit that detects a pulse wave from a pressure received by the cuff from the portion; another pulse wave detection unit that detects another pulse wave including at least an arterial pulse wave in another portion of the living body; an analyzing unit that analyzes a correlation between the two pulse waves, which are changed as the applied pressure is changed by the pressure control unit changes; and a venous pressure calculation unit that calculates a venous pressure based on the applied pressure and a result of analysis by the analyzing unit.Type: GrantFiled: April 29, 2019Date of Patent: July 7, 2020Assignee: NIHON KOHDEN CORPORATIONInventors: Teiji Ukawa, Tsuneo Takayanagi, Haruka Morimoto, Tatsuo Nishihara, Tatsuo Yoshida, Shiro Adachi, Mitsushi Hyogo