Patents Assigned to NIMBLEGEN SYSTEMS GmbH
  • DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS
    Publication number: 20140051605
    Abstract: The present disclosure relates to photoactivable protecting groups containing a diarylsulfide chromophore, a method for the synthesis thereof and their use as photoactivable protecting groups using maskless photolithography based array synthesis.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 20, 2014
    Applicant: NimbleGen Systems GmbH
    Inventor: Klaus-Peter Stengele
  • DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS
    Publication number: 20120258891
    Abstract: The present disclosure relates to photoactivable protecting groups containing a diarylsulfide chromophore, a method for the synthesis thereof and their use as photoactivable protecting groups using maskless photolithography based array synthesis.
    Type: Application
    Filed: March 29, 2012
    Publication date: October 11, 2012
    Applicant: NIMBLEGEN SYSTEMS GMBH
    Inventor: Klaus-Peter Stengele
  • Method of manufacturing labelled oligonucleotide conjugates
    Patent number: 7687618
    Abstract: The present invention relates to a method for the manufacture of labeled oligonucleotide conjugates comprising the reaction of (a) an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and (b) a labeling compound, wherein said labile protecting group is partially or completely substituted by said labeling compound in a nucleophilic substitution reaction.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: March 30, 2010
    Assignee: NIMBLEGEN SYSTEMS GmbH
    Inventors: Klaus Peter Stengele, Evgueni Kvassiouk