Patents Assigned to NIMBUS Biotechnologie GmbH
  • Patent number: 6868343
    Abstract: The invention relates to the analysis of interactions of substances or materials with surfaces or interfaces made from amphiphilic materials and in particular partition coefficients and/or binding constants are determined. For this purpose use is made of a carrier material, which is so coated with amphiphilic molecules in the so-called fluid phase that the lateral diffusion of the amphiphilic molecules is substantially unimpeded. The invention also relates to a kit suitable for such analyses, and to a process for analyzing these interactions in column chromatography, particularly high pressure or performance liquid chromatography.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: March 15, 2005
    Assignee: NIMBUS Biotechnologie GmbH
    Inventors: Thomas Bayerl, Angelika Loidl-Stahlhofen, Matthias Schoettner
  • Patent number: 6051372
    Abstract: A two-dimensional patterning of a three-dimensional surface by a template molecule (or object) involving non-covalent interactions between the template and the surface and the reversible fixation of the pattern by undergoing a phase transition in the patterned material. In this invention the surface provides a multitude of mobile functional groups (matrix) which are spatially arranged by the interaction with the template, the template selects and arranges only those groups out of a multitude of functional groups which allow for a maximum of interaction between the template and the surface. The resulting pattern is then stabilized by reducing the mobility of all functional groups present on the surface by undergoing a phase transition to a state of high surface viscosity. After separation of the template and the patterned surface, the pattern on the surface is used for recognition, separation or catalytic purposes.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: April 18, 2000
    Assignee: Nimbus Biotechnologie GmbH
    Inventors: Thomas Bayerl, Gero Decher, Thomas Braunschweig