Patents Assigned to Nimura Genetic Solutions Co., Ltd.
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Patent number: 9523082Abstract: The present invention relates to a luciferase derived from a Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 557 nm at pH 8, or the luciferase inducing luminescence having 1.5 times or more the luminous intensity of luminescence induced by Photinus pyralis firefly luciferase.Type: GrantFiled: April 11, 2014Date of Patent: December 20, 2016Assignees: OLYMPUS CORPORATION, NIMURA GENETIC SOLUTIONS CO., LTD., PERAK STATE DEVELOPMENT CORPORATIONInventors: Ryutaro Akiyoshi, Katsunori Ogo, Hirobumi Suzuki
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Patent number: 9234186Abstract: The present invention relates to a luciferase derived from a star-worm belonging to genus Diplocladon, the luciferase inducing luminescence such that a maximum luminous wavelength falls within a range of 557 to 562 nm over the entire pH range of 5.5 to 8.0, or the luciferase inducing luminescence having 1.5 times the luminous intensity of luminescence induced by Photinus pyralis firefly luciferase.Type: GrantFiled: September 13, 2013Date of Patent: January 12, 2016Assignees: OLYMPUS CORPORATION, NIMURA GENETIC SOLUTIONS CO., LTD., PERAK STATE DEVELOPMENT CORPORATIONInventors: Ryutaro Akiyoshi, Katsunori Ogo, Hirobumi Suzuki
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Publication number: 20150291938Abstract: The present invention relates to a luciferase derived from a Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 557 nm at pH 8, or the luciferase inducing luminescence having 1.5 times or more the luminous intensity of luminescence induced by Photinus pyralis firefly luciferase.Type: ApplicationFiled: April 11, 2014Publication date: October 15, 2015Applicants: OLYMPUS CORPORATION, PERAK STATE DEVELOPMENT CORPORATION, NIMURA GENETIC SOLUTIONS CO., LTD.Inventors: Ryutaro AKIYOSHI, Katsunori OGO, Hirobumi SUZUKI
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Patent number: 8722376Abstract: According to one embodiment, the present invention relates to luciferase derived from Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 580 nm at pH 8, or the luciferase indicating 23.3 times or more of luminescent intensity in comparison to that of Rhodamine 6G.Type: GrantFiled: August 20, 2012Date of Patent: May 13, 2014Assignees: Olympus Corporation, Nimura Genetic Solutions Co., Ltd., Perak State Development CorporationInventors: Katsunori Ogo, Ryutaro Akiyoshi, Hirobumi Suzuki
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Publication number: 20140073031Abstract: The present invention relates to a luciferase derived from a star-worm belonging to genus Diplocladon, the luciferase inducing luminescence such that a maximum luminous wavelength falls within a range of 557 to 562 nm over the entire pH range of 5.5 to 8.0, or the luciferase inducing luminescence having 1.5 times the luminous intensity of luminescence induced by Photinus pyralis firefly luciferase.Type: ApplicationFiled: September 13, 2013Publication date: March 13, 2014Applicants: OLYMPUS CORPORATION, PERAK STATE DEVELOPMENT CORPORATION, NIMURA GENETIC SOLUTIONS CO., LTD.Inventors: Ryutaro AKIYOSHI, Katsunori OGO, Hirobumi SUZUKI
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Publication number: 20130040326Abstract: According to one embodiment, the present invention relates to luciferase derived from Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 580 nm at pH 8, or the luciferase indicating 23.3 times or more of luminescent intensity in comparison to that of Rhodamine 6G.Type: ApplicationFiled: August 20, 2012Publication date: February 14, 2013Applicants: OLYMPUS CORPORATION, PERAK STATE DEVELOPMENT CORPORATION, NIMURA GENETIC SOLUTIONS CO., LTD.Inventors: Katsunori OGO, Ryutaro AKIYOSHI, Hirobumi SUZUKI
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Patent number: 8318684Abstract: Seven novel antibiotic substances can be produced by cultivation of a microbial strain which has been isolated from a soil sample and which is designated as Microbispora sp. A 34030 (deposited under an access number FERM BP-10505 in terms of Budapest Treaty). These seven antibiotic substances are named as bispolide A1, bispolide A2, bispolide A3, bispolide B1, bispolide B2a, bispolide B2b and bispolide B3, respectively. These bispolides are each novel compounds which have a chemical structure as collectively represented by the general formula (III) shown below: These bispolides have each a high antibacterial activity against a variety of bacteria, particularly Gram-positive bacteria and their antibiotic-resistant strains, and hence these bispolides each are effective and useful for therapeutically treating bacterial infections of Gram-positive bacteria in humans and animals.Type: GrantFiled: May 15, 2007Date of Patent: November 27, 2012Assignees: Nimura Genetic Solutions Co., Ltd., Forest Research Institute MalaysiaInventors: Keiichi Numata, Noriyuki Okujo, Siew Eim Khor, Lee Li Tan, Annie George, Szu Ting Ng, Chin Jye Tan, Hironobu Iinuma, Yasuo Fukagawa, Kunimoto Hotta, Seiji Shibahara, Shinichi Kondo, Satoshi Nimura