Abstract: The present invention provides a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including extract of Ribes fasciculatum leaves as an active ingredient, and a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including an extract of Cornus officinalis and extract of Ribes fasciculatum leaves as active ingredients.
Abstract: A pharmaceutical composition for preventing or treating female climacteric syndromes comprising Loganin which increases the concentration of estradiol (17?-estradiol, E2) in the blood of a menopausal mouse model and has shown efficacies such as an increase in the estrogen receptor alpha expression in the uterus, which remedies uterine contraction and degeneration, and decreases in the accumulation and the size of adipocytes in liver and the abdominal adipose tissues and the liver and weight loss, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
Type:
Grant
Filed:
January 13, 2017
Date of Patent:
September 14, 2021
Assignee:
NINE B CO., LTD.
Inventors:
Seon-Yong Jeong, Eun Kuk Park, Mun-Chang Kim, Jeong Hyun Kim
Abstract: The present invention provides a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including extract of Ribes fasciculatum leaves as an active ingredient, and a pharmaceutical composition and health functional food composition for preventing or treating female menopausal disease including an extract of Cornus officinalis and extract of Ribes fasciculatum leaves as active ingredients.
Type:
Application
Filed:
February 27, 2020
Publication date:
September 3, 2020
Applicants:
NINE B CO., LTD., AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Abstract: A pharmaceutical composition for preventing or treating female climacteric syndromes comprising Loganin which increases the concentration of estradiol (17?-estradiol, E2) in the blood of a menopausal mouse model and has shown efficacies such as an increase in the estrogen receptor alpha expression in the uterus, which remedies uterine contraction and degeneration, and decreases in the accumulation and the size of adipocytes in liver and the abdominal adipose tissues and the liver and weight loss, a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
Type:
Application
Filed:
January 13, 2017
Publication date:
January 3, 2019
Applicant:
NINE B CO., LTD.
Inventors:
Seon-Yong JEONG, Eun Kuk PARK, Mun-Chang KIM, Jeong Hyun KIM