Patents Assigned to NINGXIA MEDICAL UNIVERSITY
  • Patent number: 11911426
    Abstract: The disclosure provides the use of a plant in the preparation of medicines and health products for preventing and treating ovarian injury. The application found that seabuckthorn fruit pulp and seabuckthorn seed oil have good preventive and therapeutic effects on ovarian injury. Seabuckthorn fruit pulp and seabuckthorn seed oil can prevent mouse ovarian injury and estrus cycle disorders, and can improve ovarian reserve, etc. Meanwhile, they also have good therapeutic effects on the above-mentioned injuries. This application provides a basis for the prevention and treatment of ovarian injury directly by seabuckthorn fruit pulp and seabuckthorn seed oil.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: February 27, 2024
    Assignee: Ningxia Medical University
    Inventors: Rui He, Guangyong Li, Puguang Yu, Yang Niu, Huiming Ma
  • Patent number: 11827901
    Abstract: Use of Cistanche deserticola polysaccharide (CDP) in promoting the proliferation and differentiation of female germline stem cells (FGSCs) is provided. Specifically, the addition of CDP in an in vitro cultivation system can promote the proliferation and differentiation of FGSCs, and especially can enhance the in vitro directed differentiation of FGSCs into oocytes, which provides a new research reference for studying the generation of oocytes in vivo and in vitro and also brings a new hope for research on physiological infertility.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: November 28, 2023
    Assignee: Ningxia Medical University
    Inventors: Xiuying Pei, Xiaoli Yu, Yikai Qiu, Ji Wu, Jianqiang Yu, Yanrong Wang, Xinrui Liu, Jing Pu
  • Publication number: 20210386810
    Abstract: The disclosure provides the use of a plant in the preparation of medicines and health products for preventing and treating ovarian injury. The application found that seabuckthorn fruit pulp and seabuckthorn seed oil have good preventive and therapeutic effects on ovarian injury. Seabuckthorn fruit pulp and seabuckthorn seed oil can prevent mouse ovarian injury and estrus cycle disorders, and can improve ovarian reserve, etc. Meanwhile, they also have good therapeutic effects on the above-mentioned injuries. This application provides a basis for the prevention and treatment of ovarian injury directly by seabuckthorn fruit pulp and seabuckthorn seed oil.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 16, 2021
    Applicant: Ningxia Medical University
    Inventors: Rui He, Guangyong Li, Puguang Yu, Yang Niu, Huiming Ma
  • Publication number: 20210371814
    Abstract: Use of Cistanche deserticola polysaccharide (CDP) in promoting the proliferation and differentiation of female germline stem cells (FGSCs) is provided. Specifically, the addition of CDP in an in vitro cultivation system can promote the proliferation and differentiation of FGSCs, and especially can enhance the in vitro directed differentiation of FGSCs into oocytes, which provides a new research reference for studying the generation of oocytes in vivo and in vitro and also brings a new hope for research on physiological infertility.
    Type: Application
    Filed: March 25, 2021
    Publication date: December 2, 2021
    Applicant: Ningxia Medical University
    Inventors: Xiuying PEI, Xiaoli YU, Yikai QIU, Ji WU, Jianqiang YU, Yanrong WANG, Xinrui LIU, Jing PU
  • Patent number: 11007196
    Abstract: A method for preparing a composition of matter, the method including: 1) mixing a Zn(NO3)2 solution, a Hg(NO3)2 solution, and a mercaptopropionic acid solution, thereby yielding a precursor solution of Zn2+—Hg2+-mercaptopropionic acid; dissolving a selenium powder and a NaBH4 solid in water thereby yielding a NaHSe slurry; mixing the precursor solution and the NaHSe slurry thereby yielding zinc-mercury-selenium (ZnHgSe) quantum dot; 2) preparing a drug delivery system including dextran-magnetic layered double hydroxide-fluorouracil (DMF); binding the drug delivery system and the ZnHgSe quantum dot in a mass ratio of 1:1-3; and grinding the drug delivery system including the ZnHgSe quantum dot (QD) thereby yielding powders; and 3) dissolving the powders in absolute ethyl alcohol thereby yielding a first suspension; ultrasonically dispersing the first suspension thereby yielding a second suspension, magnetically separating the second suspension thereby yielding a solid product, centrifuging and washing the soli
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: May 18, 2021
    Assignee: NINGXIA MEDICAL UNIVERSITY
    Inventors: Guojing Gou, Xueqin Jin, Rui Wang, Qinyu Pei, Huiqin Yao, Yumei Zhang, Lingxia Zuo
  • Publication number: 20130108589
    Abstract: The present invention belongs to the field of cell transplantation. Particularly, the present invention provides a method of producing neurons for treating injuries with the loss of neuron function from stem cells, wherein the stem cell is a human derived mesenchymal stem cell, preferably human derived placental mesenchymal stem cell, bone marrow mesenchymal stem cell, adipose mesenchymal stem cell and liver mesenchymal stem cell. The present invention also provides the uses of said method and the nerve cells produced by said method in the preparation of medicines for treating injuries with the loss of neuron function and in the treatment of injuries with the loss of neuron function. The present invention further provides a method of treating injuries with the loss of neuron function.
    Type: Application
    Filed: July 22, 2010
    Publication date: May 2, 2013
    Applicant: AFFILIATED HOSPITAL OF NINGXIA MEDICAL UNIVERSITY
    Inventors: Yinxue Yang, Jun Wei, Yukui Li, Libin Wang, Lijun Ma, Ting Liu, Xiaona Ma, Heng Fan, Yongzhao Zhu, Ping Ye, Yiran Jin
  • Publication number: 20100272694
    Abstract: The present invention relates to a method for processing human placental cell sample, a human placental cell sample obtained according to said method for processing human placental cell sample, a human placental cell bank, a method for banking human placental cells, a method for searching human placental cell sample in said human placental cell bank according to the present invention, a method for preparing human cord blood serum, use of human placental cells obtained by said method for processing human placental cell sample or human placental cell bank established by said method for banking human placental cells in treating human dysfunction and diseases due to cell injury or cell malfunction, as well as a method for treating human dysfunction and diseases due to cell injury or cell malfunction.
    Type: Application
    Filed: October 17, 2008
    Publication date: October 28, 2010
    Applicant: AFFILIATED HOSPITAL OF NINGXIA MEDICAL UNIVERSITY
    Inventors: Yinxue Yang, Jun Wei, Yukui Li, Libin Wang, Ting Liu, Xiaona Ma, Guangyi Zhang