Patents Assigned to Nippon Fine Chemical Co., Ltd.
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Publication number: 20230348750Abstract: The present invention provides a coating agent composition capable of making interference fringes inconspicuous and suppressing the generation of cracks during the production of a hard coat layer without blending fine particles of metal oxides such as zirconium oxide and titanium oxide in an optical article in which a hard coat layer or a functional layer including a primer layer and a hard coat layer is formed on a plastic layer having a high refractive index. The coating agent composition comprises a trifunctional silane coupling agent and a bifunctional silane coupling agent in a solid content ratio of 95:5 to 10:90.Type: ApplicationFiled: October 16, 2020Publication date: November 2, 2023Applicant: NIPPON FINE CHEMICAL CO., LTD.Inventors: Kou Oishi, Toshiya Ueno, Yoshiaki Miyamoto
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Publication number: 20230312620Abstract: The present invention provides a charge-reversible phospholipid that is not positively charged at a pH of the body fluid (typically in the neutral range) and has low cytotoxicity. The present invention provides a phospholipid represented by formula (1): wherein m represents a natural number of 9 to 25, n represents a natural number of 10 to 15, X1, X2, and X3 are the same or different and each represent H or OH, and R1 represents the following formula (i) or (ii): wherein p represents 1 or 2, q represents 1 or 2, and r represents an integer of 1 to 4; or wherein s represents an integer of 1 to 3, and R2 represents a hydrogen atom or a hydrocarbon group.Type: ApplicationFiled: June 2, 2022Publication date: October 5, 2023Applicant: NIPPON FINE CHEMICAL CO., LTD.Inventors: Koji Tomita, Yuki Inoue, Ayano Yokouchi, Sae Asayama, Naofumi Fukata
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Publication number: 20230295199Abstract: Provided is a charge-reversible and ethanol-soluble phospholipid suitable for the preparation of lipid particles. A phospholipid represented by formula (1): wherein R1 and R2 are the same or different and each represent a chain hydrocarbon group, R3 represents a hydrogen atom or a hydrocarbon group, and m represents an integer of 1 to 3.Type: ApplicationFiled: March 1, 2022Publication date: September 21, 2023Applicant: NIPPON FINE CHEMICAL CO., LTD.Inventors: Koji Tomita, Yuki Inoue, Ayano Yokouchi, Naofumi Fukata, Noriyuki Maeda
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Publication number: 20220380562Abstract: The present invention provides a composition for forming a hard coat and a laminate using the same. The composition for forming a hard coat includes at least metal oxide fine particles; a hydrolysate of an organosilicon compound; an adhesion promoting component having an alkoxysilyl group; a curing catalyst; and a solvent, wherein by introducing, as the organosilicon compound, an organosilicon compound having a hydrocarbon group having (6 to 18) carbon atoms substituted with a glycidoxy group, and an organosilicon compound having a hydrocarbon group having (1 to 5) carbon atoms substituted with a glycidoxy group, even when applied to a flexible resin substrate, the composition for forming a hard coat has excellent adhesion and scratch resistance, and bending resistance (crack resistance) and surface hardness as well.Type: ApplicationFiled: June 16, 2020Publication date: December 1, 2022Applicant: NIPPON FINE CHEMICAL CO., LTD.Inventors: Hiroyoshi Warabino, Yoshiaki Miyamoto, Toshiya Ueno
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Patent number: 11034708Abstract: An object is to provide a lipid particle that is not positively charged at a pH of the body fluid (typically in the neutral range), and that enables efficient onset of the effect of a medicinal substance encapsulated in the lipid particle; and to provide a lipid for forming the lipid particle. The object is achieved by the phospholipid represented by formula (1), and a lipid particle containing the phospholipid: wherein R1 and R2 are identical or different, and represent a chain hydrocarbon group, m represents 1 or 2, n represents 1 or 2, and p represents an integer of 1 to 4.Type: GrantFiled: March 1, 2018Date of Patent: June 15, 2021Assignees: NIPPON FINE CHEMICAL CO., LTD., SHIZUOKA PREFECTURAL UNIVERSITY CORPORATIONInventors: Tomohiro Asai, Naoto Oku, Noriyuki Maeda, Naofumi Fukata, Koji Tomita
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Publication number: 20200031853Abstract: An object is to provide a lipid particle that is not positively charged at a pH of the body fluid (typically in the neutral range), and that enables efficient onset of the effect of a medicinal substance encapsulated in the lipid particle; and to provide a lipid for forming the lipid particle. The object is achieved by the phospholipid represented by formula (1), and a lipid particle containing the phospholipid: wherein R1 and R2 are identical or different, and represent a chain hydrocarbon group, m represents 1 or 2, n represents 1 or 2, and p represents an integer of 1 to 4.Type: ApplicationFiled: March 1, 2018Publication date: January 30, 2020Applicants: NIPPON FINE CHEMICAL CO., LTD., SHIZUOKA PREFECTURAL UNIVERSITY CORPORATIONInventors: Tomohiro ASAI, Naoto OKU, Noriyuki MAEDA, Naofumi FUKATA, Koji TOMITA
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Patent number: 7427640Abstract: An oil material comprising a dimerdiol ester with a monocarboxylic acid having 4 to 34 carbon atoms or with a dimerdiol ester with a dicarboxylic acid; and a cosmetic and an external agent excellent in safety, stability, gloss, feeling and the like comprising the dimerdiol carboxylate.Type: GrantFiled: June 26, 2000Date of Patent: September 23, 2008Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Tsuyoshi Katayama, Masakazu Okumura, Nobuaki Hattori, Makoto Nakajima, Osamu Kimura
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Publication number: 20070154340Abstract: A lubricant for powder metallurgy which includes a polyhydroxycarboxylic acid amide. The lubricant improves both flowability and lubricity, irrespective of a presence or absence of any complicated pretreatment step.Type: ApplicationFiled: January 19, 2005Publication date: July 5, 2007Applicants: Kabushiki Kaisha Kobe Seiko Sho, Nippon Fine Chemical Co., Ltd.Inventors: Hironori Suzuki, Kazuhisa Fujisawa, Takayasu Fujiura, Kiyoshi Horie, Masaki Kojima, Takeshi Yoshihara
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Patent number: 6183759Abstract: An acylated peptide or a salt thereof obtainable by condensing a protein-derived peptide with a lanolin-derived non-hydroxyl fatty acid containing 30-45% by weight of iso-type fatty acid of the following formula (I), 30-50% by weight of anteiso-type fatty acid of the following formula (II), 10-30% by weight of normal type fatty acid of the following formula (III): CH3˜CH (CH3)—(CH2) n-COOH (n=6˜2 7) (I) CH3CH2—CH (CH3)—(CH2)n-COOH (n=6˜2 6) (II) CH3-(CH2) n-COOH (n=8˜2 8) (III) and less than 10% by weight of hydroxyl fatty acid, the total amount of said iso-type fatty acid and said anteiso-type fatty acid being at least 60% by weight; and a cosmetic composition for hair or skin containing the acylated peptide or a salt thereof; and the cosmetic composition gives excellent moist feel and gloss and the like to hair and an excellent feeling on use, such as smoothness and moistness to skin.Type: GrantFiled: April 27, 1998Date of Patent: February 6, 2001Assignees: Nippon Fine Chemical Co., Ltd., Seiwa Kasei Co., Ltd.Inventors: Nobuaki Hattori, Masakazu Okumura, Masato Yoshioka, Sueko Kobayashi
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Patent number: 5686636Abstract: The invention provides a process for preparing high-purity cholesterol, the process comprising selectively reducing the impurities (mainly desmosterol) contained in a crude cholesterol to cholesterol.According to the invention, high-purity cholesterol can be obtained in a yield of at least 85%, the cholesterol containing 0.3% or less of desmosterol, 0.5% or less of dihydrocholesterol and having a purity of at least 99% after reduction and crystallization.Type: GrantFiled: August 14, 1995Date of Patent: November 11, 1997Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Takeshi Osada, Katsunori Myojyo
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Patent number: 5173554Abstract: The present invention provides a glycoside derivative represented by the formula ##STR1## wherein G--O-- is a saccharide residue having no protective group, R is a hydrogen atom or a methyl group, m is 1 or 2, n is an integer of 1 to 4, and l is an integer of 1 or more provided that l.ltoreq.n; a polymer containing the glycoside derivative; a process for their preparation, and the use of the polymers.Type: GrantFiled: May 21, 1992Date of Patent: December 22, 1992Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Sadaya Kitazawa, Masakazu Okumura, Masaki Kojima, Keisuke Kinomura, Toshiyuki Sakakibara
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Patent number: 5169636Abstract: The invention provides liposomes characterized in that the lipid membrane thereof contains a glycolipid resulting from O-glycoside or S-glycoside bonding of a lipid and at least one carbohydrate selected from the group consisting of uronic acids, uronosyl-oligosaccharides, oligosaccharides composed of glucosamine and glucuronic acid, oligosaccharides composed of galactosamine and glucuronic acid, oligosaccharides composed of glucuronic acid and xylose, oligosaccharides composed of glucuronic acid and glucose, oligosaccharides composed of glucuronic acid and galactose, oligosaccharides composed of glucuronic acid and mannose, oligosaccharides composed of galacturonic acid and rhamnose, ketoaldonic acids, 2-acetamido-2-deoxyuronic acids, 2-acetamido-2-deoxyuronic acid-containing oligosaccharides, 6-O-carboxyethyl-.beta.-D-glucose, 6-O-carboxymethyl-.beta.-D-glucose, 6'-O-carboxymethyl-.beta.-D-maltose and 6'-O-carboxyethyl-.beta.-D-maltose.Type: GrantFiled: November 14, 1989Date of Patent: December 8, 1992Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Yukihiro Nanba, Toshiyuki Sakakibara, Naoto Oku
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Patent number: 5164492Abstract: The present invention provides a glycoside derivative represented by the formula ##STR1## wherein G--O-- is a saccharide residue having no protective group, R is a hydrogen atom or a methyl group, m is 1 or 2, n is an integer of 1 to 4, and l is an integer of 1 or more provided that l.ltoreq.n; a polymer containing the glycoside derivative; a process for their preparation, and the use of the polymers.Type: GrantFiled: June 26, 1990Date of Patent: November 17, 1992Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Sadaya Kitazawa, Masakazu Okumura, Masaki Kojima, Keisuke Kinomura, Toshiyuki Sakakibara
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Patent number: 5096629Abstract: The present invention provides(1) a method for preparing lipid powder for use in the preparing liposome, which comprises supplying at a constant speed an organic solvent solution of lipids having liposome membrane forming ability to a tubular heater heated externally, evaporating the organic solvent in the heater to prepare a mixture substantially of solids and organic solvent vapor and introducing this mixture at a high speed into a vacuum chamber of not more than 300 mm Hg, to volatilize the organic solvent instantaneously and dry the solids, and(2) a method for preparing liposomes comprising dispersing the lipid powder obtained by the above method (1) into an aqueous solvent.Type: GrantFiled: August 28, 1989Date of Patent: March 17, 1992Assignee: 501 Nippon Fine Chemical Co., Ltd.Inventors: Yukihiro Nanba, Toshiya Ueno, Toshiyuki Sakakibara
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Patent number: 4874852Abstract: Disclosed are a glycosidation catalyst comprising at least one of heteropoly acids represented by the formulaH.sub.a X.sub.p M.sub.q O.sub.r .multidot.bH.sub.2 Owherein X is P, As, Si or Ge, M is at least one species selected from the group consisting of Mo, W and V, a is 3 4 or 6, b is an integer of 0 to 30, p is 1 or 2, q is 12 or 18, and r is 40 or 62, with the proviso that when X is P or As, a is 3 or 6; when X is Si or Ge, a is 4; and further (1) when X is P or As and a is 3, or when X is Si or Ge and a is 4, M is at least one species selected from the group consisting of Mo, W and V, p is 1, q is 12 and r is 40; and (2) when X is P or As and a is 6, M is Mo or W, p is 2, q is 18 and r is 62, and a process for preparing a glycoside derivative by using said catalyst.Type: GrantFiled: March 10, 1989Date of Patent: October 17, 1989Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Keisuke Kinomura, Sadaya Kitazawa, Yasushi Takata, Toshiyuki Sakakibara
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Patent number: 4690784Abstract: This invention provides a process for preparing a phosphatidylcholine derivative represented by the formula ##STR1## wherein R represents straight- or branched-chain andsaturated or unsaturated hydrocarbon group, the process comprising the steps of(i) providing a suspension or solution of glycerophosphatidylcholine and a carrier in a solvent and removing the solvent from the suspension or solution by distillation to obtain a powder, and(ii) reacting the glycerophosphatidylcholine present in the powder with an acid anhydride or acid halide in a solvent and in the presence of a basic catalyst to acylate the glycerophosphatidylcholine.Type: GrantFiled: May 28, 1985Date of Patent: September 1, 1987Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Yukihiro Nanba, Toshiyuki Sakakibara
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Patent number: 4291098Abstract: This invention provides a composition for coating plastics articles comprising (A) a hydrolyzed product of an organoalkoxysilane represented by the formulaR.sup.1.sub.n Si(OR.sup.2).sub.4-n (I)wherein R.sup.1 is a saturated or unsaturated hydrocarbon residue having 1 to 4 carbon atoms, R.sup.2 is a saturated hydrocarbon residue having 1 to 4 carbon atoms, and n is 0, 1 or 2, (B) an epoxy resin having an epoxy equivalent of about 120 to about 700, and (C) a bicyclic amidine represented by the formula ##STR1## wherein m is 3 or 5, or a salt thereof; a method of coating plastics articles with use of the composition; and plastics articles having a cured coating of the composition.Type: GrantFiled: January 9, 1980Date of Patent: September 22, 1981Assignees: Nippon Fine Chemical Co., Ltd., Nippon Aspherical Lens Co., Ltd.Inventors: Mitsuaki Tanaka, Masaharu Suzuki