Patents Assigned to Nippon Kayaku Co., Ltd.
  • Patent number: 11267787
    Abstract: [Problem] The present invention provides a method for producing and isolating a target quinolone derivative using general industrial facilities with high purity. [Solving means] The present invention also provides a method for producing a quinolone derivative, the method including reacting a ketone with an anthranilic acid derivative using an aluminum halide and removing the aluminum halide under basic conditions.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: March 8, 2022
    Assignees: NIPPON KAYAKU CO., LTD, MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Akinori Morikawa, Hirokazu Kuroda, Kazumi Yamamoto, Nozomu Nakanishi
  • Publication number: 20210219552
    Abstract: Disclosed is a wettable agrochemical composition comprising an agrochemical active component (A), which is a compound represented by the following formula (I) or an agriculturally and horticulturally acceptable acid addition salt thereof, one or more additives, and one or more surfactants, the wettable agrochemical composition being solid at 30° C. This wettable agrochemical composition has excellent physical properties of the formulation and storage stability.
    Type: Application
    Filed: June 7, 2019
    Publication date: July 22, 2021
    Applicants: NIPPON KAYAKU CO., LTD., MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Yoshinori MURAMATSU, Hidetoshi SHIRAKURA, Atsushi SATO, Mitsuyuki YABUZAKI, Shigeru UENO
  • Publication number: 20210070710
    Abstract: [Problem] The present invention provides a method for producing and isolating a target quinolone derivative using general industrial facilities with high purity. [Solving means] The present invention also provides a method for producing a quinolone derivative, the method including reacting a ketone with an anthranilic acid derivative using an aluminum halide and removing the aluminum halide under basic conditions.
    Type: Application
    Filed: December 12, 2018
    Publication date: March 11, 2021
    Applicants: NIPPON KAYAKU CO., LTD., MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Akinori MORIKAWA, Hirokazu KURODA, Kazumi YAMAMOTO, Nozomu NAKANISHI
  • Patent number: 10758484
    Abstract: The present invention discloses a method for administering SN-38-loaded polymeric micelles into the central nervous system of a human subject via a convection-enhanced delivery system. The convection-enhanced delivery is achieved by using an osmotic pump or an infusion pump. Further, SN-38-loaded polymeric micelles are administered into a target region of the brain of the subject.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: September 1, 2020
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Ryuta Saito, Teiji Tominaga
  • Publication number: 20180214375
    Abstract: The present invention discloses a method for administering SN-38-loaded polymeric micelles into the central nervous system of a human subject via a convection-enhanced delivery system. The convection-enhanced delivery is achieved by using an osmotic pump or an infusion pump. Further, SN-38-loaded polymeric micelles are administered into a target region of the brain of the subject.
    Type: Application
    Filed: August 24, 2015
    Publication date: August 2, 2018
    Applicant: Nippon Kayaku Co., Ltd.
    Inventors: Ryuta Saito, Teiji Tominaga
  • Patent number: 9869805
    Abstract: The present invention has the objective of providing an infrared reflective film by means of which it is possible to achieve an effective heat-shielding performance with a smaller number of layers than hitherto using a construction employing specified infrared reflective layers. Solution Means The infrared reflective film of the present invention has at least two infrared reflective layers and, of these infrared reflective layers, the center reflective wavelength of at least one infrared reflective layer is between 1200 and 1300 nm. Furthermore, the laminated glass of the present invention is formed by interposing this infrared reflective film between two sheets of intermediate film, and laminating these between two sheets of glass.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: January 16, 2018
    Assignees: Nippon Kayaku Co., Ltd., BASF SE, Central Glass Co., Ltd.
    Inventors: Kouichi Tanaka, Hideyoshi Fujisawa, Kensuke Izutani, Satoshi Nishiyama, Atsushi Takamatsu, Akira Matsumoto, Masayoshi Furukawa
  • Patent number: 9485987
    Abstract: The present invention provides an aqueous suspended agricultural chemical composition comprising an agricultural chemical active ingredient, an alkyl naphthalene sulfonate formalin condensate and one or two or more compounds selected from the group consisting of an alkyl sulfate, a polyoxyalkylene alkyl ether sulfate, an alkyl phosphoric acid and a salt thereof, a polyoxyalkylene alkyl ether phosphoric acid and a salt thereof, and a polyoxyalkylene alkyl ether acetic acid and a salt thereof. The aqueous suspended agricultural chemical composition suppresses the crystal growth of the agricultural chemical active ingredient, and has an excellent effect on pest control and an excellent storage stability.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: November 8, 2016
    Assignees: MEIJI SEIKA PHARMA CO., LTD., NIPPON KAYAKU CO., LTD.
    Inventors: Atsushi Sato, Mitsuyuki Yabuzaki, Shigeru Ueno, Yoshinori Muramatsu, Kazuteru Ogawa, Hidetoshi Shirakura
  • Publication number: 20160085002
    Abstract: The present invention has the objective of providing an infrared reflective film by means of which it is possible to achieve an effective heat-shielding performance with a smaller number of layers than hitherto using a construction employing specified infrared reflective layers. Solution Means The infrared reflective film of the present invention has at least two infrared reflective layers and, of these infrared reflective layers, the center reflective wavelength of at least one infrared reflective layer is between 1200 and 1300 nm. Furthermore, the laminated glass of the present invention is formed by interposing this infrared reflective film between two sheets of intermediate film, and laminating these between two sheets of glass.
    Type: Application
    Filed: May 23, 2014
    Publication date: March 24, 2016
    Applicants: Nippon Kayaku Co., Ltd., BASF SE, Central Glass Co., Ltd.
    Inventors: Kouichi TANAKA, Hideyoshi FUJISAWA, Kensuke IZUTANI, Satoshi NISHIYAMA, Atsushi TAKAMATSU, Akira MATSUMOTO, Masayoshi FURUKAWA
  • Patent number: 9126934
    Abstract: An objective of the present invention is to provide a process for producing 4-carbonyl oxyquinoline derivatives useful as agricultural and horticultural pesticides and fungicides. The objective can be attained by a process for producing 4-carbonyl oxyquinoline derivatives represented by general formula (1), the process including reacting a quinolone derivative with a halogenated compound or an acid anhydride in the presence of a phase transfer catalyst and a base.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: September 8, 2015
    Assignees: NIPPON KAYAKU CO., LTD., MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Shizuo Shimano, Akinori Morikawa, Kenichi Yamamoto, Hiroki Hotta, Kazumi Yamamoto, Nozomu Nakanishi, Nobuto Minowa
  • Patent number: 8648195
    Abstract: An objective of the present invention is to provide a crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate having stable physicochemical properties. The objective is attained by a crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate that exhibits a diffraction peak pattern shown in FIG. 1 as determined by powder X-ray diffractometry.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: February 11, 2014
    Assignees: Nippon Kayaku Co., Ltd., Meiji Seika Pharma Co., Ltd.
    Inventors: Kouki Tanigakiuchi, Mikio Sekiguchi, Hiroki Hotta, Shizuo Shimano, Akinori Morikawa, Kazumi Yamamoto, Nozomu Nakanishi, Nobuto Minowa, Takashi Watanabe
  • Publication number: 20130245271
    Abstract: An objective of the present invention is to provide a process for producing 4-carbonyl oxyquinoline derivatives useful as agricultural and horticultural pesticides and fungicides. The objective can be attained by a process for producing 4-carbonyl oxyquinoline derivatives represented by general formula (1), the process including reacting a quinolone derivative with a halogenated compound or an acid anhydride in the presence of a phase transfer catalyst and a base.
    Type: Application
    Filed: November 16, 2011
    Publication date: September 19, 2013
    Applicants: MEIJI SEIKA PHARMA CO., LTD., NIPPON KAYAKU CO., LTD.
    Inventors: Shizuo Shimano, Akinori Morikawa, Kenichi Yamamoto, Hiroki Hotta, Kazumi Yamamoto, Nozomu Nakanishi, Nobuto Minowa
  • Patent number: 8367833
    Abstract: Disclosed is a process for producing 6-aryloxyquinoline derivatives useful as insecticides or fungicides for agricultural and horticultural use. The process comprises a cyclization reaction step of reacting an anthranilic acid derivative represented by general formula (1) with a kenone in the presence of an acid to obtain a quinolone derivative and a condensation reaction step of reacting the quinolone derivative with a halogen compound or an acid anhydride to obtain a quinoline derivative.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: February 5, 2013
    Assignees: Nippon Kayaku Co., Ltd., Meiji Seika Pharma Co., Ltd.
    Inventors: Yasuhito Kato, Shizuo Shimano, Akinori Morikawa, Hiroki Hotta, Kazumi Yamamoto, Nozomu Nakanishi, Nobuto Minowa, Hiroshi Kurihara
  • Patent number: 7880006
    Abstract: Disclosed are compounds that have excellent insecticidal activity and are usable as agricultural and horticultural insecticides. Compounds represented by formula (I) or agriculturally and horticulturally acceptable acid addition salts thereof have excellent insecticidal activity and are usable as agricultural and horticultural insecticides.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: February 1, 2011
    Assignees: Meiji Seika Kaisha, Ltd., Nippon Kayaku Co., Ltd.
    Inventors: Kazumi Yamamoto, Ryo Horikoshi, Kazuhiko Oyama, Hiroshi Kurihara, Shizuo Shimano, Takaaki Miyake, Hiroki Hotta, Jun Iwabuchi
  • Patent number: 7282324
    Abstract: Photoresist compositions that demonstrate superior photolithographic performance and hardened resist films that show superior resistance to solvents, have excellent resistance to under plating during the electrodeposition of metals, and show excellent resist stripping characteristics. These photoresist compositions according to the invention are well-suited as for applications in the manufacture of MEMS and micromachine devices. These photoresist compositions according to the invention comprise one or more epoxide-substituted, polycarboxylic acid Resin Component (A), one or more photoacid generator compounds (B), and one or more solvent (C).
    Type: Grant
    Filed: January 3, 2005
    Date of Patent: October 16, 2007
    Assignees: MicroChem Corp., Nippon Kayaku Co., Ltd.
    Inventors: William Weber, Satoshi Mori, Nao Honda
  • Publication number: 20070203181
    Abstract: Disclosed are compounds that have excellent insecticidal activity and are usable as agricultural and horticultural insecticides. Compounds represented by formula (I) or agriculturally and horticulturally acceptable acid addition salts thereof have excellent insecticidal activity and are usable as agricultural and horticultural insecticides.
    Type: Application
    Filed: August 3, 2005
    Publication date: August 30, 2007
    Applicants: MEIJI SEIKA KAISHA, LTD., NIPPON KAYAKU CO., LTD.
    Inventors: Kazumi Yamamoto, Ryo Horikoshi, Kazuhiko Oyama, Hiroshi Kurihara, Shizuo Shimano, Takaaki Miyake, Hiroki Hotta, Jun Iwabuchi
  • Patent number: 6794031
    Abstract: A cover-lay film comprising a heat-resistant film and an adhesive layer, wherein the adhesive layer is formed of an epoxy resin composition containing (a) an epoxy resin, (b) a curing agent, (c) a phenolic hydroxyl-containing polyamide-poly(butadiene-acrylonitrile) copolymer, and (d) an ion capturing agent and having a glass transition temperature of 80° C. or higher after cure, and the heat-resistant film mainly comprises a polyimide containing a 3,3′,4,4′-biphenyltetracarboxylic acid component and a p-phenylenediamine component and has a specific coefficient of linear thermal expansion and a specific tensile modulus in both machine and transverse directions.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: September 21, 2004
    Assignees: Ube Industries, Ltd., Nippon Kayaku Co., Ltd.
    Inventors: Tooru Murakami, Toyofumi Asano, Masahiro Imaizumi
  • Patent number: 6399606
    Abstract: Neuroprotective agents are disclosed having the following structure: wherein R1, R2, R3, R4 and R5 are as defined herein. Such compounds have utility in the treatment of conditions which benefit from administration of neuroprotective agents generally, including treatment of central and peripheral nervous condition as well as for promoting nerve cell differentiation. Methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more of the compounds of this invention.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: June 4, 2002
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Moorthy S. S. Palanki, Shripad S. Bhagwat, Hiroshi Sato, Paul E. Erdman, Mary Doubleday
  • Patent number: 6340772
    Abstract: Three processes are described for preparing (hetero)aromatic substituted benzene derivatives which comprise aromatization of cyclohexenone derivatives via (chloro)cyclohexadiene derivatives.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: January 22, 2002
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Tetsuya Toya, Hidetoshi Shirakura, Junichi Kon
  • Patent number: 6271418
    Abstract: Three processes are described for preparing (hetero)aromatic substituted benzene derivatives which comprise aromatization of cyclohexenone derivatives via (chloro)cyclohexadiene derivatives.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: August 7, 2001
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Tetsuya Toya, Hidetoshi Shirakura, Junichi Kon
  • Patent number: 6114364
    Abstract: The present invention relates to a compound represented by the following general formula (1) ##STR1## (wherein X represents O, S, SO, SO.sub.2, or NH, Y is a substituted or unsubstituted hydrocarbon residue containing 1 through 6 carbon atoms and having an overall molecular weight of not less than 15 and not more than 400, and the hydrocarbon residue, when the residue is ring, may contain one or two hetero-atoms in the ring, and Z is a carboxyl group, a group derived therefrom or an aliphatic hydrocarbon residue having from 1 to 4 carbon atoms which may be substituted or unsabstituted) or a pharmacologically acceptable salt thereof (excluding (1R,2S)-2-[(2R)-(2-acetyl-amino-2-carboxyethyl)thiomethyl]-3-oxo-1-cyclope ntane-carboxylic acid (cystacyclin)), a method for production thereof and a medicinal use thereof. The compound of the present invention is useful as a neuron differentiation accelerator.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: September 5, 2000
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Seiichi Saito, Tomio Morino, Kuniko Masuda