Patents Assigned to Nippon Soda Company Limited
  • Patent number: 5204255
    Abstract: A hybrid plasminogen activator-like polypeptide comprising a polypeptide region responsible for an affinity to fibrin derived from a tissue plasminogen activator polypeptide and a polypeptide region responsible for an enzyme activity derived from a prourokinase polypeptide; a DNA segment coding for the hybrid polypeptide; plasmid containing the DNA segment; a microorganism transformed with the DNA; and a process for production of the hybrid polypeptide comprising culturing the microorganism and recovering the hybrid polypeptide from the cultured cells.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: April 20, 1993
    Assignees: Sagami Chemical Research Center, Central Glass Company, Limited, Hodogaya Chemical Co., Ltd., Nippon Soda Company, Limited, Nissan Chemical Industries, Limited, Toyo Soda Manufacturing Co., Ltd.
    Inventors: Michito Tagawa, Masakatsu Wada, Masayuki Yamada, Midori Yokoyama, Naganori Numao
  • Patent number: 5188829
    Abstract: A human prourokinase-like polypeptide having the following amino acid sequence:(Met).Ser.sup.1 -X.sup.156.Y.sup.157.Z.sup.158 --wherein Met is an occasionally present methionine, Ser is the first N-terminal serine, X is the 156th arginine or other amino acid, Y is the 157th proline, glycine, alanine or valine, Z is the 158th lysine or arginine, and the solid lines represent the same amino acid sequences as corresponding parts of an amino acid sequence of a natural type human prourokinase or a human prourokinase-like polypeptide wherein the 135th lysine is changed to an amino acid other than a basic amino acid, or substantially the same amino acid sequence as the above-mentioned amino acid sequence, is provided.Moreover, a DNA segment coding for the above-mentioned polypeptide; a plasmid containing the DNA segment; E. coli transformed with the plasmid; a process for production of the polypeptide characterized by culturing the E.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: February 23, 1993
    Assignees: Sagami Chemical Research Center, Central Glass Company, Limited, Hodogaya Chemical Co., Ltd., Nippon Soda Company, Limited, Nissan Chemical Industries, Limited, Tosoh Corporation
    Inventors: Yo-ichi Kobayashi, Muneki Omori, Chikako Yamada
  • Patent number: 4970157
    Abstract: An isolated gene coding for phenylalanine dehydrogenase of a microorganism belonging to a genus selected from the group consisting of the genera Bacillus and Sporosarcina origin; plasmids containing the gene; microorganism transformed with the plasmid, a process for the production of phenylalanine dehydrogenase using the microogranism; and a process for the production of L-phenylalanine using the enzyme.
    Type: Grant
    Filed: August 11, 1987
    Date of Patent: November 13, 1990
    Assignees: Sagami Chemical Research Center, Central Glass Company, Limited, Hodogaya Chemical Co., Ltd., Nippon Soda Company, Limited, Nissan Chemical Industries, Limited, Toyo Soda Manufacturing Co., Ltd.
    Inventors: Yasuo Hibino, Yasuhisa Asano, Noriko Okazaki, Naganori Numao
  • Patent number: 4568766
    Abstract: 4-Hydroxy-4'-isopropoxydiphenylsulfone useful as color developer for heat-sensitive color-developable recording material.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: February 4, 1986
    Assignee: Nippon Soda Company Limited
    Inventors: Masakichi Yahagi, Tetsuo Igaki, Shinji Yoshinaka, Kosaku Morita, Kimiaki Kinoshita, Masashi Enokiya, Akio Kaneko, Toshiyuki Yamashita
  • Patent number: 4532363
    Abstract: There is a method for the production of 3-phenylpyrrole derivatives having the general formula ##STR1## wherein X is halogen, nitro or haloalkyl having 1 to 3 carbon atoms;n is 0, 1 or 2; andZ is hydrogen or halogen;which comprises reacting a compound having the general formula ##STR2## wherein X and n are as previously defined; andY is hydrogen or halogen;with ammonia or aqueous ammonia in an organic solvent.A compound having the general formula [I] is useful as fungicide or intermediate thereof.
    Type: Grant
    Filed: May 30, 1984
    Date of Patent: July 30, 1985
    Assignee: Nippon Soda Company Limited
    Inventors: Akiyoshi Ueda, Humiko Nagasaki, Yutaka Takakura, Shigeru Kojima
  • Patent number: 4529552
    Abstract: Composite oxyalkoxides and their derivatives are novel organometallic compounds which give alkaline earth metal titanates such as barium titanate or strontium titanate by hydrolysis or thermal decomposition. The oxyalkoxides are synthesized by the reaction between an alkoxytitanium and an alkaline earth metal hydroxide, and their derivatives are synthesized by the reaction between the composite oxyalkoxide and a chelating agent.
    Type: Grant
    Filed: January 24, 1983
    Date of Patent: July 16, 1985
    Assignee: Nippon Soda Company Limited
    Inventors: Iwao Kato, Yoshihiko Nakamura, Tetsuo Yoshimoto, Masanori Iwamori, Kazuo Ozawa, Makoto Asai
  • Patent number: 4515729
    Abstract: A cyclohexane derivative having the formula ##STR1## wherein R.sub.1 is C.sub.1-4 alkyl or halo phenyl;R.sub.2 is C.sub.1-3 alkyl or cyano group;R.sub.3 is C.sub.1-4 alkyl;R.sub.4 is C.sub.1-4 alkyl or C.sub.1-4 alkenyl;X is straight or branched chain C.sub.1-4 alkylene; andn is 0, 1 or 2,which possess herbicidal properties, and the process for its preparation.
    Type: Grant
    Filed: January 26, 1983
    Date of Patent: May 7, 1985
    Assignee: Nippon Soda Company Limited
    Inventors: Isao Iwataki, Kagari Fujita, Hisao Ishikawa, Hideo Hosaka, Kenichi Kohara
  • Patent number: 4482740
    Abstract: A compound having the general formula ##STR1## wherein R.sub.1 is ethyl or allyl; andR.sub.2 is alkyl having 1-4 carbon atoms;and a metal salt of the compound defined herein above.The compound is useful as herbicides.
    Type: Grant
    Filed: December 27, 1982
    Date of Patent: November 13, 1984
    Assignee: Nippon Soda Company Limited
    Inventors: Isao Iwataki, Akira Nakayama, Minoru Kaeriyama, Hisao Ishikawa, Hideo Hosaka, Kenichi Kohara, Shozo Yamada
  • Patent number: 4476303
    Abstract: Compounds having the formula ##STR1## wherein R.sub.1 denotes hydrogen atom, halogen group atom or methyl radical,R.sub.2 denotes cyclohexyl radical, phenyl radical or phenyl radical substituted with methyl radical or nitro radical, andX denotes oxygen atom or sulfur atom,are useful for the control of phytophthora diseases and downy mildew of vegetable and fruit trees.The compounds of formula [I] can be prepared by reacting compounds having the formula ##STR2## wherein R.sub.1, R.sub.2 and X are defined previously, are reacted with a carbonic acid derivative in the presence of an acid-binding agent.
    Type: Grant
    Filed: February 8, 1983
    Date of Patent: October 9, 1984
    Assignee: Nippon Soda Company Limited
    Inventors: Kuniyasu Maeda, Minoru Kaeriyama, Nobuo Matsui, Masami Mizuno, Yasushi Yasuda, Akira Nakata
  • Patent number: 4471126
    Abstract: There is a method for the production of 3-phenylpyrrole derivatives having the general formula ##STR1## wherein X is halogen, nitro or haloalkyl having 1 to 3 carbon atoms;n is 0, 1 or 2; andZ is hydrogen or halogen;which comprises reacting a compound having the general formula ##STR2## wherein X and n are as previously defined; andY is hydrogen or halogen;with ammonia or aqueous ammonia in an organic solvent.A compound having the general formula [I] is useful as fungicide or intermediate thereof.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: September 11, 1984
    Assignee: Nippon Soda Company Limited
    Inventors: Akiyoshi Ueda, Humihiko Nagasaki, Yutaka Takakura, Shigeru Kojima
  • Patent number: 4442116
    Abstract: A compound of the formula ##STR1## wherein typical representations of X, Y and Z is oxygen or sulfur; R.sub.1 is methyl; R.sub.2 is phenyl substituted with chlor, methyl, methoxy, nitro or methylenedioxy; and R.sub.3 is cyclohexyl, methylcyclohexyl or tetrahydropyranyl, is useful as an acaricide.
    Type: Grant
    Filed: February 19, 1982
    Date of Patent: April 10, 1984
    Assignee: Nippon Soda Company, Limited
    Inventors: Isao Iwataki, Minoru Kaeriyama, Nobuo Matsui, Tomio Yamada
  • Patent number: 4433079
    Abstract: Water-dispersion adhesives stable in storage and dilution dispersion and excellent in adhesive properties for extrusion lamination which comprise a dispersion of a resin in water, wherein the resin (A) is obtained from a reaction of a polyepoxy compound (B) with a reaction mixture (C) of a polyethyleneimine (D) and a monoepoxy compound (E).
    Type: Grant
    Filed: March 9, 1983
    Date of Patent: February 21, 1984
    Assignee: Nippon Soda Company Limited
    Inventors: Noriyuki Kobayashi, Akihiko Funamoto
  • Patent number: 4431814
    Abstract: A compound of the formula ##STR1## wherein typical representations of X, Y and Z is oxygen or sulfur; R.sub.1 is methyl; R.sub.2 is phenyl substituted with chlor, methyl, methoxy, nitro or methylenedioxy; and R.sub.3 is cyclohexyl, methylcyclohexyl or tetrahydropyranyl, is useful as an acaricide.
    Type: Grant
    Filed: February 16, 1982
    Date of Patent: February 14, 1984
    Assignee: Nippon Soda Company Limited
    Inventors: Isao Iwataki, Minoru Kaeriyama, Nobuo Matsui, Tomio Yamada
  • Patent number: 4391743
    Abstract: An organic solution of a composition consisting essentially of 100 parts of an indium compound represented by the formulaIn(X).sub.l (Y).sub.mwherein X denotes a chelate ring formed by .beta.-diketones, esters of .beta.-ketoacids or the like, Y denotes an alkoxide formed by aliphatic alcohols or the like, and l and m denote an integer which is either 1 or 2 having the relationship of l+m=3, and from 5 to 20 parts of a tin compound represented by the formulaSn(X').sub.2 or Sn(Y')m'wherein X' denotes a chelate ring formed by .beta.-diketones or esters of .beta.-ketoacids, Y' denotes an alkoxide formed by aliphatic alcohols, and m' denotes 2 or 4, is suitable for deposition of transparent, hardened and low resistivity film coatings of tin-doped indium oxide on a substrate by dipcoating.
    Type: Grant
    Filed: November 30, 1981
    Date of Patent: July 5, 1983
    Assignee: Nippon Soda Company Limited
    Inventors: Umio Maeda, Hirofumi Shoji, Yasusuke Wada, Yoshio Horie
  • Patent number: 4355184
    Abstract: .alpha., .beta.-unsaturated-ketones are synthesized by reacting with an aldehyde and an alkali metal salt of acetoacetic acid in the presence of an aliphatic secondary amine in the mixture of heterogeneous solvents producing an oil layer and a water layer.
    Type: Grant
    Filed: April 27, 1981
    Date of Patent: October 19, 1982
    Assignee: Nippon Soda Company Limited
    Inventors: Tsutomu Kaku, Kiyoshi Katsuura, Mikio Sawaki
  • Patent number: 4346098
    Abstract: A fungicidal composition containing as the active component a mixture of (I) a compound having the formula of ##STR1## wherein R.sub.1 is methylene or C.sub.2-4 alkylene, andR.sub.2 is C.sub.1-4 alkyl,and(II) a compound having the formula of ##STR2## wherein R.sub.3 is C.sub.1-2 alkyl.
    Type: Grant
    Filed: December 5, 1980
    Date of Patent: August 24, 1982
    Assignee: Nippon Soda Company Limited
    Inventors: Yasushi Yasuda, Masami Mizuno, Hiroaki Nishikawa, Akira Murakami
  • Patent number: 4336196
    Abstract: Sodium salts of phenylmalonic acid mono-esters are produced by reacting a phenylacetic acid ester with carbon dioxide in the presence of a sodium substituted compound, which is prepared by substituting a sodium atom for a hydrogen atom of an organic compound selected from a group consisting of acetylene, cumene, triphenylmethane, methyl-methylthiomethyl-sulfoxide and dimethyl-sulfoxide, at a temperature in a range of -20.degree. C. to -40.degree. C.
    Type: Grant
    Filed: July 21, 1980
    Date of Patent: June 22, 1982
    Assignees: Nippon Soda Company Limited, Shionogi Company Limited
    Inventors: Shigeo Kitamura, Kazuo Yoshioka, Yoshiharu Seriyama, Hiroshi Misuta
  • Patent number: 4326881
    Abstract: Compounds of the general formula ##STR1## wherein Xn is 2-Cl, 3-Cl, 2,3-Cl.sub.2 or 3-CF.sub.3, andR is hydrogen or acetyl,with the proviso that Xn is 2,3-Cl.sub.2 in the case of R being hydrogen, are outstanding effective fungicides.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: April 27, 1982
    Assignee: Nippon Soda Company Limited
    Inventors: Akiyoshi Ueda, Hideo Takagi, Kazuhiko Ohkuma
  • Patent number: 4321363
    Abstract: Highly pure urokinase can be produced by affinity chromatography on a novel adsorbent which comprises a water insoluble carrier and a ligand united to the carrier. The ligand is shown by the general formula ##STR1## wherein X is oxygen, sulfur or imino group, and R is amino or carboxyl group.
    Type: Grant
    Filed: February 21, 1980
    Date of Patent: March 23, 1982
    Assignee: Nippon Soda Company Limited
    Inventors: Daigaku Takiguchi, Eiji Itou, Hiroaki Nakamura, Izumi Kumita
  • Patent number: 4316044
    Abstract: Isovaleric acid derivatives having the formula ##STR1## wherein typical representations of X is halophenyl, R.sub.1 is hydrogen or cyano, R.sub.2 is hydrogen or lower alkyl, and Y is halophenyl. These derivatives possess insecticidal and acaricidal properties. The process for their preparation is described.
    Type: Grant
    Filed: August 29, 1980
    Date of Patent: February 16, 1982
    Assignee: Nippon Soda Company Limited
    Inventors: Keiichi Ishimitsu, Isamu Kasahara, Tomio Yamada, Michihiko Matsuda, Hidemitsu Takahashi, Shuichi Soma