Abstract: A photo-spectroscopic analytic device is given for detecting analytes in a sample. The analyte may be microbial pathogen, a food sample, a sample of a body fluid, water, or a combination thereof. The device comprises an electromagnetic radiation (EMR) source in operative communication with one or more optic inputs, one or more receptors for receiving one or more sample holders, each receptor comprising one or more of the optic inputs which are operatively coupled to one or more optic outputs thereby forming an optic input-optic output pair. Each of the receptors may comprise different cross-sectional profiles corresponding to cross-sectional profiles of the sample holders.