Patents Assigned to Nissan Chemical Industries Limited
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Publication number: 20140051857Abstract: A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: October 28, 2013Publication date: February 20, 2014Applicant: Nissan Chemical Industries LimitedInventors: Shingo OWADA, Shunsuke Iwamoto, Kazufumi Yanagihara, Katsuaki Miyaji, Takanori Nakamura, Norihisa Ishiwata, Yutaka Hirokawa
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Publication number: 20140023798Abstract: To provide a liquid crystal aligning agent useful to obtain a liquid crystal alignment film excellent in liquid crystal alignment properties, alignment controlling power and rubbing resistance, having high voltage retention characteristics and having reduced charge accumulation, and a liquid crystal display device which is less susceptible to display failure, to lowering of contrast or to image persistence. A liquid crystal aligning agent comprising a low resistance polyimide precursor having a volume resistivity of from 1×1010 to 1×1014 ?cm when formed into a film, and a high alignment polyimide precursor or polyimide having a specific structure, and a liquid crystal display device employing this liquid crystal aligning agent.Type: ApplicationFiled: September 26, 2013Publication date: January 23, 2014Applicant: Nissan Chemical Industries LimitedInventors: Kimiaki Tsutsui, Takahiro Sakai, Kohei Goto
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Publication number: 20130012708Abstract: A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: September 13, 2012Publication date: January 10, 2013Applicant: Nissan Chemical Industries LimitedInventors: Shingo Owada, Shunsuke Iwamoto, Kazufumi Yanagihara, Katsuaki Miyaji, Takanori Nakamura, Norihisa Ishiwata, Yutaka Hirokawa
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Publication number: 20110077290Abstract: A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: June 26, 2009Publication date: March 31, 2011Applicant: Nissan Chemical Industries LimitedInventors: Shingo OWADA, Shunsuke Iwamoto, Kazufumi Yanagihara, Katsuaki Miyaji, Takanori Nakamura, Norihisa Ishiwata, Yutaka Hirokawa
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Publication number: 20100310537Abstract: An object of the present invention is to expand CD34+ cells ex vivo efficiently in a short term using a biologically safe and inexpensively obtainable low molecular weight compound. A still another object of the present invention is to provide an expansion agent for CD34+ cells useful for treatment of various hematopoietic disorders caused by dysfunctional hematopoietic stem cells and/or hematopoietic progenitor cells. A method for expanding CD34+ cells, which comprises culturing CD34+ cells ex vivo in the presence of a compound represented by the formula (I) (wherein A, B, L1, L2, L3, L4, R1, R2, R3, X and Y are defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: December 5, 2008Publication date: December 9, 2010Applicant: Nissan Chemical Industries LimitedInventors: Takanori Nakamura, Atsushi Miyamura, Taito Nishino, Norihisa Ishiwata, Katsuaki Miyaji
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Publication number: 20100310536Abstract: An object of the present invention is to expand CD34+ cells ex vivo efficiently in a short term using a biologically safe and inexpensively obtainable low molecular weight compound. A still another object of the present invention is to provide an expansion agent for CD34+ cells useful for treatment of various hematopoietic disorders caused by dysfunctional hematopoietic stem cells and/or hematopoietic progenitor cells. A method for expanding CD34+ cells, which comprises culturing CD34+ cells ex vivo in the presence of a compound represented by the formula (I) (wherein A, B, L1, L2, L3, L4, R1, R2, R3, X and Y are defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: December 5, 2008Publication date: December 9, 2010Applicant: Nissan Chemical Industries LimitedInventors: Takanori Nakamura, Atsushi Miyamura, Taito Nishino, Norihisa Ishiwata, Katsuaki Miyaji
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Publication number: 20100312000Abstract: To provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) from the corresponding amino compound having a carboxyl group(s). A method for producing an isothiocyanate compound which has a carboxyl group(s) and is represented by the formula (2). And the method comprises reacting an amino compound which has a carboxyl group(s) and is represented by the formula (1) (wherein A is e.g. a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group, and B is e.g. a single bond, a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group), in a solvent, with carbon disulfide (CS2) and then with a halogen as a simple substance.Type: ApplicationFiled: February 27, 2009Publication date: December 9, 2010Applicant: Nissan Chemical Industries LimitedInventors: Satoshi Nakano, Daisuke Saito
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Publication number: 20090220707Abstract: To provide a liquid crystal aligning agent useful to obtain a liquid crystal alignment film excellent in liquid crystal alignment properties, alignment controlling power and rubbing resistance, having high voltage retention characteristics and having reduced charge accumulation, and a liquid crystal display device which is less susceptible to display failure, to lowering of contrast or to image persistence. A liquid crystal aligning agent comprising a low resistance polyimide precursor having a volume resistivity of from 1×1010 to 1×1014 ?cm when formed into a film, and a high alignment polyimide precursor or polyimide having a specific structure, and a liquid crystal display device employing this liquid crystal aligning agent.Type: ApplicationFiled: July 15, 2008Publication date: September 3, 2009Applicant: Nissan Chemical Industries LimitedInventors: Kimiaki Tsutsui, Takahiro Sakai, Kohei Goto
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Publication number: 20080027068Abstract: A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or is pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: August 13, 2007Publication date: January 31, 2008Applicant: Nissan Chemical Industries LimitedInventors: Shingo OWADA, Shunsuke IWAMOTO, Kazufumi YANAGIHARA, Katsuaki MIYAJI, Takanori NAKAMURA, Norihisa ISHIWATA, Yutaka HIROKAWA
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Publication number: 20070267966Abstract: A composite thin film-holding substrate for a surface light emitter, which is a transparent substrate including a composite thin film containing fine particles and a binder formed on the surface of a transparent base material. The refractive index of the composite thin film is higher than the refractive index of the transparent base material. The difference in the refractive index between the fine particles and the binder contained in the composite thin film is at least 0.1, and the ratio of (solid content mass of the fine particles)/(solid content mass of the binder+solid content mass of the fine particles) of the composite thin film is from 0.01 to 0.5. A surface light emitter can use the substrate.Type: ApplicationFiled: May 24, 2005Publication date: November 22, 2007Applicant: Nissan Chemical Industries LimitedInventors: Satoru Numajiri, Kenichi Motoyama
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Publication number: 20070155897Abstract: To provide a process for forming an improved coating film on a substrate, particularly to provide a coating film formed on a substrate, as adhered to the surface of the substrate, having a refractive index of from 1.28 to 1.38 and a contact angle with water of from 90° to 115°. A coating film having a refractive index of from 1.28 to 1.38 and a contact angle with water of from 90° to 115°, which is formed as adhered to a substrate surface by forming a reaction mixture comprising a silicon compound (A) of the formula Si(OR)4, a silicon compound (B) of the formula (R1O)3SiCH2CH2(CF2)nCH2CH2Si(OR1)3, an alcohol (C) of the formula R2CH2OH, and oxalic acid (D), in a specific ratio; heating this reaction mixture at a temperature of from 50 to 180° C. in the absence of water, to form a solution of a polysiloxane; then applying a coating fluid comprising the polysiloxane solution on a substrate surface to form a coating; and heat-curing the coating at a temperature of from 80 to 450° C.Type: ApplicationFiled: December 17, 2004Publication date: July 5, 2007Applicant: Nissan Chemical Industries LimitedInventors: Yoshihiro Tani, Kenichi Motoyama
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Publication number: 20060094694Abstract: A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13 SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: December 6, 2005Publication date: May 4, 2006Applicant: Nissan Chemical Industries LimitedInventors: Shingo Owada, Shunsuke Iwamoto, Kazufumi Yanagihara, Katsuaki Miyaji, Takanori Nakamura, Norihisa Ishiwata, Yutaka Hirokawa
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Patent number: 6835805Abstract: A method of production of a homopolymer or copolymer or homo-oligomer or co-oligomer product characterised in that the product is obtained by condensation reaction of a diaminoanthracene, substituted or not, optionally with a diiminoanthracene substituted or not in the absence of anthraquinone substituted or not.Type: GrantFiled: November 26, 2001Date of Patent: December 28, 2004Assignee: Nissan Chemical Industries LimitedInventors: Poopathy Kathirgamanathan, Subramaniam Ganeshamurugan
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Publication number: 20040086724Abstract: A stable modified metal oxide sol which contains from 2 to 50 wt %, as calculated as metal oxides, of particles (c) comprising colloidal particles (a) of a metal oxide having primary particle diameters of from 2 to 60 nm, as nuclei, and a coating material (b) consisting of colloidal particles of an acidic oxide coated on the surface of the particles (a), and which has primary particle diameters of from 2 to 100 nm.Type: ApplicationFiled: June 25, 2003Publication date: May 6, 2004Applicant: Nissan Chemical Industries LimitedInventors: Keitaro Suzuki, Yoshinari Koyama, Motoko Iijima
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Publication number: 20040018235Abstract: The present invention is drawn to a pharmaceutical composition characterized by containing a composition (A) which contains pitavastatin, a salt thereof, or an ester thereof and which initiates release thereof at least in the stomach, and an enteric composition (B) which contains pitavastatin, a salt thereof, or an ester thereof. By use of the controlled release pharmaceutical composition of the present invention, the blood level of pitavastatin can be maintained at an appropriate level immediately after administration over a long period of time. Thus, highly safety and effective treatment of hypercholesterolemia can be performed.Type: ApplicationFiled: June 16, 2003Publication date: January 29, 2004Applicants: KOWA CO., LTD, Nissan Chemical Industries LimitedInventors: Yoshio Tanizawa, Tatsuharu Shimokawa, Hirotada Ogawa, Mayumi Watanabe, Chihiro Ohashi, Hiroyuki Kawashima, Yasuo Shinoda, Toshio Inagi
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Publication number: 20020111485Abstract: Optically active &bgr;-type tris-(2,3-epoxypropyl)-isocyanurate is obtained by a method of reacting isocyanuric acid with an optically active epihalohydrin, or a method of optically resolving a racemic modification of tris-(2,3-epoxypropyl)-isocyanurate by using an amylose or cellulose derivative. It is a method for producing a high melting point type tris-(2,3-epoxypropyl)-isocyanurate obtained by mixing two enantiomers of optically active &bgr;-type tris-(2,3-epoxypropyl)-isocyanurate.Type: ApplicationFiled: April 9, 2002Publication date: August 15, 2002Applicant: Nissan Chemical Industries LimitedInventors: Hisao Ikeda, Motohiko Hidaka, Atsumi Aoki
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Publication number: 20020095013Abstract: A method of production of a homopolymer or copolymer or homo-oligomer or co-oligomer product characterised in that the product is obtained by condensation reaction of a diaminoanthracene, substituted or not, optionally with a diiminoanthracene substituted or not in the absence of anthraquinone substituted or not.Type: ApplicationFiled: November 26, 2001Publication date: July 18, 2002Applicant: Nissan Chemical Industries LimitedInventors: Poopathy Kathirgamanathan, Subramaniam Ganeshamurugan
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Patent number: 5380900Abstract: Disclosed herein is an .alpha.-methylene-cyclopentanone derivative represented by the formula [I] below which is useful as an intermediate for pharmaceuticals and insecticides, especially prostaglandins. Also disclosed herein is a process for producing the derivative advantageously on an industrial scale. ##STR1## where X denotes (.alpha.-OZ, .beta.-H) or (.alpha.-H, .beta.-OZ), with Z representing a protecting group for the hydroxyl group; U denotes (.alpha.-H, .beta.-R.sup.1) or (.beta.-R.sup.1, .alpha.-H); R.sup.1 denotes ##STR2## where R.sup.2 denotes a protected hydroxyl group, a substituted or unsubstituted C.sub.1-15 alkyl group, a substituted or unsubstituted C.sub.2-15 alkenyl group, a substituted or unsubstituted C.sub.2-15 alkynyl group, or a substituted or unsubstituted C.sub.6-15 aryl group; Z' denotes a protecting group for the hydroxyl group; and k is 0 or 1).Type: GrantFiled: February 12, 1992Date of Patent: January 10, 1995Assignee: Nissan Chemical Industries, LimitedInventors: Fumie Sato, Kazutaka Arai, Katsuaki Miyaji
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Patent number: 5292693Abstract: A sheet-forming slurry composition is composed of zirconia powder, an organic binder, and a solvent. The zirconia powder contains 2 to 10 mol % of yttria in solid solution form and has a BET specific surface area of up to about 12 m.sup.2 /g and a mean particle size multiplied by the specific surface area of up to 3 .mu.m.m.sup.2 /g. The composition is formed into a green sheet having improved flexibility, binder removal capability, sinterability, and dimensional stability, which is then fired into a sintered part having improved denseness, gas barrier property, and surface smoothness.Type: GrantFiled: February 20, 1992Date of Patent: March 8, 1994Assignee: Nissan Chemical Industries, LimitedInventors: Takao Kaga, Yuzi Hoshi, Yutaka Kimura
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Patent number: 5204255Abstract: A hybrid plasminogen activator-like polypeptide comprising a polypeptide region responsible for an affinity to fibrin derived from a tissue plasminogen activator polypeptide and a polypeptide region responsible for an enzyme activity derived from a prourokinase polypeptide; a DNA segment coding for the hybrid polypeptide; plasmid containing the DNA segment; a microorganism transformed with the DNA; and a process for production of the hybrid polypeptide comprising culturing the microorganism and recovering the hybrid polypeptide from the cultured cells.Type: GrantFiled: July 3, 1991Date of Patent: April 20, 1993Assignees: Sagami Chemical Research Center, Central Glass Company, Limited, Hodogaya Chemical Co., Ltd., Nippon Soda Company, Limited, Nissan Chemical Industries, Limited, Toyo Soda Manufacturing Co., Ltd.Inventors: Michito Tagawa, Masakatsu Wada, Masayuki Yamada, Midori Yokoyama, Naganori Numao