Patents Assigned to Nisshin Oil Mills, Ltd.
  • Patent number: 5380829
    Abstract: Disclosed are thioglycoside analogs of gangliosides represented by the formula ##STR1## in which Y represents a radical of the following formula ##STR2## and X represents a radical of the formula ##STR3## wherein m is an integer of 15 to 25, l is an integer of 0 to 3 and n is an integer of 11 to 15. The thioglycoside analogs are expected to exert specific enzyme-inhibitory effects.
    Type: Grant
    Filed: February 27, 1992
    Date of Patent: January 10, 1995
    Assignees: The Nisshin Oil Mills, Ltd., Akira Hasegawa
    Inventors: Akira Hasegawa, Makoto Kiso
  • Patent number: 5371202
    Abstract: An improved process for the preparation of O-glycosyl compounds of sialic acid, which are useful as intermediates in the synthesis of sialoconjugated glycosides. This process comprises effecting condensation reaction between thioglycosides of sialic acid and sugar derivatives in the presence of N-iodosuccinimide and trifluoromethanesulfonic acid. O-glycosyl compounds of sialic acid are prepared in high resio- and stereo-selectivity and in high yields.
    Type: Grant
    Filed: February 12, 1992
    Date of Patent: December 6, 1994
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventor: Akira Hasegawa
  • Patent number: 5369096
    Abstract: Disclosed are glycolipid derivatives of formula (I) ##STR1## wherein X is a group selected from ##STR2## n is 0 or an integer of 1-10 and R denotes a branched hydrocarbon chain containing from 19 to 39 carbon atoms. Those compounds are useful as antiinflammatory agents, or as agents for the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: November 29, 1994
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Yutaka Yamada, Naofumi Takahashi, Keisuke Adachi, Akihiko Kameyama
  • Patent number: 5305476
    Abstract: A shower bathing device comprising a passage through which hot water is passed, a chamber filled with a medical solution to supply the medical solution into the passage, a stream pump for mixing the medical solution in the chamber with hot water passing through the passage, and a screw inserted into a through hole for adjusting the amount of the medical solution supplied to the stream pump, wherein hot water can be showered while including a desired density of medicine therein.
    Type: Grant
    Filed: April 15, 1993
    Date of Patent: April 26, 1994
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Keiichi Ohyama, Ayami Inaba, Takashi Murata
  • Patent number: 5252761
    Abstract: A branched monoester represented by the formula R.sup.1 COOR.sup.2 acts as a silicone-dissolving or solubilizing agent. In the formula, R.sup.1 is an isoalkyl group having 4 to 17 carbon atoms, and R.sup.2 is an isoalkyl group having 3 to 18 carbon atoms.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: October 12, 1993
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Tadashiro Hirose, Yoshihiro Ueda, Yoshiaki Takagi
  • Patent number: 5227403
    Abstract: A nutrient comprising fats and oils having superior digestibility and absorptivity are provided, which fats and oils are comprised of at least one triglyceride having fatty acids of C.sub.8 to C.sub.14 at the 2-position of the triglyceride and identical unsaturated acids of C.sub.18 or higher at both the 1- and 3-positions thereof. Examples of the unsaturated fatty acids of C.sub.18 or higher are linolic acid, linolenic acid, arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid.
    Type: Grant
    Filed: October 23, 1991
    Date of Patent: July 13, 1993
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Akira Seto, Osamu Yamada
  • Patent number: 5183675
    Abstract: A process for producing a salad oil comprises transesterifying a mixture of (A) an oil or fat produced from palm oil and having the following characteristics:______________________________________ iodine value: 55 to 75 constituent fatty acids: palmitic acid: 30 to 42% by weight oleic acid: 42 to 48% by weight linoleic acid: 11 to 20% by weight tripalmitin: 2% by weight or less open-tube melting point: 5 to 25.degree. C. ______________________________________and (B) a liquid edible oil other than the component (A) in a weight ratio of 5:95 to 95:5 with immobilized lipase having 1,3-specificity in the absence of solvent and then fractionating the product in the absence of solvent. Thereby, the salad oil can be efficiently derived from palm oil which is a solid oil and the relative amount of the starting material obtained from palm oil in the salad oil can be increased. The thus-produced salad oil has a satisfactory cooling resistance.
    Type: Grant
    Filed: July 9, 1991
    Date of Patent: February 2, 1993
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Koichi Tamura, Nobuo Taguchi, Satoshi Tashiro
  • Patent number: 5176909
    Abstract: A stable immunogen composition for oral administration which includes a dried spherical form comprised of an immunogen capable of immunizing human or animals and a gelatin having an average molecular weight of 80,000-120,000 and jelly strength of more than 150 (Bloom, g, 6.2/3%), and is enteric.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: January 5, 1993
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Kuniaki Nerome, Kuniharu Seki, Katsuhiko Ohyama
  • Patent number: 5100787
    Abstract: A method for preparing highly purified phosphatidylinositol comprises the steps of treating a mixed phospholipid with a phospholipase D, then treating the product with an alkali or acidic phosphatase and separating unreated phosphatidylinositol from the reaction mixture. The method makes it possible to isolate phosphatidylinositol useful in various fields in a high purity in the order of 80 to 99%.
    Type: Grant
    Filed: July 30, 1990
    Date of Patent: March 31, 1992
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Shoichi Shimizu, Tsuneo Yamane, Dongxiu Li, Lekh R. Juneja
  • Patent number: 5081048
    Abstract: An agent or device for the determination of antigen or antibody comprising capsules of a water-insoluble, dye-permeable polymer or a liquor-pool covered by said polymer, an antien, antibody or hapten immobilized on the surface of said polymer, and a dye solution enclosed or held in said capsules or liquor-pool, and a method for determining antigen or antibody using said agent or device, which can be conveniently used for the serodiagnosis of various diseases.
    Type: Grant
    Filed: March 10, 1989
    Date of Patent: January 14, 1992
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Yoshio Okahata, Naofumi Takahashi, Takuro Sada
  • Patent number: 5077202
    Abstract: A process for producing a glycolipid having a high eicosapentaenoic acid (EPA) content is provided, which process comprises fractionating the whole lipids of marine chlorella by means of a combination of solvent-fractionation with column chromatography, which glycolipid has platelet agglutination-inhibiting effect, serum cholesterol-increase-inhibiting effect, etc. of EPA and also having a higher absorption rate in intestinal canal than EPA triglyceride or ethyl ester.
    Type: Grant
    Filed: August 28, 1985
    Date of Patent: December 31, 1991
    Assignee: Nisshin Oil Mills, Ltd.
    Inventors: Akira Seto, Kiyohiro Kitagawa, Shoko Yamashita, Tadasu Fujita
  • Patent number: 5026644
    Abstract: A lipid composition having a high .gamma.-linolenic acid content is prepared by culturing mold fungi of the genus Cunninghamella in an aqueous nutrient culture medium having a relatively high concentration of a carbon source, and the lipid composition is recovered from the cultured mold fungi.
    Type: Grant
    Filed: September 6, 1989
    Date of Patent: June 25, 1991
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Yumiko Manoh, Akira Seto
  • Patent number: 4956109
    Abstract: Herein disclosed is a lubricating oil comprising at least one member selected from the group consisting of esterified products obtained by reacting: (A) a compound selected from the group consisting of alcohols represented by the following general formula (I), alcohols represented by the following general formula (II) and hydrogenated derivatives thereof; with (B) a fatty acid having not less than 6 carbon atoms or a mixture of the fatty acid with a rosin selected from the group consisting of rosin, hydrogenated rosins, disproportionated rosins and polymerized rosins: ##STR1## in the general formulas (I) and (II), X.sub.1 and X.sub.2 each independently represents a hydrogen atom or a methyl group and n is an integer ranging from 0 to 10. The lubricating oil is used as rolling mill oils, hydraulic oils cutting-grinding oils, lubricating oils for metal plastic working and those for internal combustion engines.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: September 11, 1990
    Assignees: The Nisshin Oil Mills, Ltd., Nippon Steel Corporation
    Inventors: Keiichi Tanikawa, Higaki Yuzo
  • Patent number: 4954443
    Abstract: Enzymes or microorganisms are immobilized by bringing a first aqueous solution into contact with a second aqueous solution containing metal ions having a valence of 3 or more. The first solution contains enzymes or microorganisms, and at least one immobilizing agent selected from the group consisting of Xanthan gum and derivatives thereof. The immobilizing agent is thereby hardened in a state to enclose the enzymes or microorganisms. Preferably, the metal ions are iron, tin, manganese or titanium ions.
    Type: Grant
    Filed: November 18, 1988
    Date of Patent: September 4, 1990
    Assignee: The Nisshin Oil Mills, LTD.
    Inventors: Osamu Yamada, Tadasu Fujita
  • Patent number: 4931291
    Abstract: Feeds comprising unicellular algaes whose cell wall are disrupted are provided as the feeds for larvae of crustaceans and shellfishes to be cultivated. With such feeds, it is possible to achieve the rates of survival and growth equivalent to, or higher than, those achieved with untreated diatom.
    Type: Grant
    Filed: July 12, 1988
    Date of Patent: June 5, 1990
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Eiji Kojima, Kiyohiro Kitagawa, Akira Seto
  • Patent number: 4906479
    Abstract: A feedstuff for cultivating Artemia as a feedstuff for larvae of cultivated fishes or crustaceans is provided, which feedstuff for cultivation is a product obtained by treatment of breaking the cell wall of monocellular algae, the thus obtained Artemia having a high survival rate, the body length thereof being large and the content of eisacopentaenoic acid and docosahexaenoic acid in the total fatty acids therein being much higher than those of conventional feedstuffs.
    Type: Grant
    Filed: May 11, 1988
    Date of Patent: March 6, 1990
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventors: Kiyohiro Kitagawa, Eiji Kojima, Akira Seto, Shuichi Sakamoto, Takuji Nozawa
  • Patent number: 4897280
    Abstract: A processed soybean curd (tofu) food having a texture similar to meat. The food contains soybean curd and a fibrous soybean protein material mixed therein. The protein material is prepared by using a single or twin screw extruder.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: January 30, 1990
    Assignee: The Nisshin Oil Mills, Ltd.
    Inventor: Hideo Ohtsu
  • Patent number: 4895835
    Abstract: Muramyl peptide derivatives having the formula (I) ##STR1## wherein R.sub.3 is a long chain acyloxyacyl group, R.sub.1 is hydrogen or hydroxy mercapto, acyloxy or acylthio group, R.sub.2 is hydrogen or alkyl group and R.sub.4 is acyl, which are useful as immunomodulators.
    Type: Grant
    Filed: November 17, 1988
    Date of Patent: January 23, 1990
    Assignee: Nisshin Oil Mills, Ltd.
    Inventor: Akira Hasegawa
  • Patent number: 4891161
    Abstract: A cold rolling mill lubricant for steel sheets, contains a monoester oil represented by general formula (A):R.sup.1 COO--(R.sup.2 --O).sub.n --R.sup.3(Wherein R.sup.1 is an alkyl, alkenyl, hydroxyalkyl, or hydroxyalkenyl group having 7 or more carbon atoms, R.sup.2 is an alkylene group, R.sup.3 is an alkyl or phenyl group, and n is an integer of 1 to 5), and/or a diester oil represented by general formula (B): ##STR1## (wherein each R.sup.4 or R.sup.6 is independently an alkyl, alkenyl, hydroxyalkyl or hydroxyalkenyl group having 5 or more carbon atoms, R.sup.5 is an alkylene group having 2 to 4 carbon atoms, and m is an integer of 1 or more).
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: January 2, 1990
    Assignees: Nisshin Oil Mills, Ltd., Nippon Steel Corp.
    Inventors: Keiichi Tanikawa, Yuji Fujioka, Yuzo Higaki, Hiroyuki Goto
  • Patent number: 4889648
    Abstract: Lubricating oils for rolling of steel plates, which are composed of synthetic ester compounds obtainable from tri- or higher-valent alcohols having tertiary nitrogen such as isocyanuric derivatives or ethylene oxide addition products of ethylenediamine and fatty acids, possess well-balanced rolling lubricating properties and mill cleanability at a high level.
    Type: Grant
    Filed: July 18, 1988
    Date of Patent: December 26, 1989
    Assignees: The Nisshin Oil Mills, Ltd., Nippon Steel Corporation
    Inventors: Yuzo Higaki, Hiroyuki Goto, Keiichi Tanikawa