Patents Assigned to NitroSystems, Inc.
  • Method of stimulating nitric oxide synthase
    Patent number: 6465516
    Abstract: A method for treating a subject who would benefit from increased nitric oxide production comprising administering inhibitors of Hmg-CoA-Reductase is disclosed for the treatment of diseases related to endothelial dysfunction.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: October 15, 2002
    Assignee: Nitrosystems, Inc.
    Inventor: Wayne H. Kaesemeyer
  • Therapeutic mixture useful in inhibiting lesion formation after vascular injury
    Patent number: 6425881
    Abstract: Vessels are treated with a mixture of L-arginine and an agent which enhances the biotransformation of L-arginine into NO. The incidents associated with restenosis are expected to be substantially reduced and prevented providing for a reduced incidence of restenosis as a result of the injury.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: July 30, 2002
    Assignee: Nitrosystems, Inc.
    Inventor: Wayne H. Kaesemeyer
  • Formulations for treating disease and methods of using same
    Patent number: 6239172
    Abstract: A therapeutic mixture comprised of L-arginine and angiogenic growth factors is disclosed for the treatment of diseases related to endothelial dysfunction.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: May 29, 2001
    Assignee: NitroSystems, Inc.
    Inventor: Wayne H. Kaesemeyer
  • Method and formulation for treating vascular disease
    Patent number: 5968983
    Abstract: A therapeutic mixture comprised of L-arginine and inhibitors of Hmg--CoA-Reductase is disclosed for the treatment of diseases related to endothelial dysfunction, wherein the endothelial dysfunction is relieved by stimulating the constitutive form of nitric oxide synthase (cNOS) to produce native nitric oxide (NO).
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: October 19, 1999
    Assignee: Nitrosystems, Inc
    Inventor: Wayne H. Kaesemeyer