Abstract: The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit the ClC-1 ion channel.
Type:
Application
Filed:
December 14, 2017
Publication date:
June 20, 2019
Applicant:
NMD Pharma ApS
Inventors:
Lars J.S. Knutsen, Martin E. Cooper, Andrew W. Brown
Abstract: The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit the ClC-1 ion channel. The compounds include phenoxy propanoic acid, phenoxy propanoate, and phenoxy butanoate compounds.
Type:
Application
Filed:
December 14, 2017
Publication date:
June 20, 2019
Applicant:
NMD Pharma ApS
Inventors:
Lars J.S. Knutsen, Thomas Holm Pedersen, Claus Elsborg Olesen, Marc A. Labelle, Paul Brian Little, Martin E. Cooper, Neerja Saraswat, Dastagiri Dudekula, Rafiq A. Taj
Abstract: The present invention relates to compositions comprising compounds for use in treating, ameliorating and/or preventing neuromuscular disorders. The compounds as defined herein preferably inhibit the ClC-1 ion channel. The invention further relates to methods of treating, preventing and/or ameliorating neuromuscular disorders, by administering said composition to a person in need thereof.
Type:
Application
Filed:
June 15, 2016
Publication date:
April 12, 2018
Applicant:
NMD PHARMA APS
Inventors:
Thomas HOLM PEDERSEN, Martin BROCH-LIPS, Claus ELSBORG OLESEN, Marc LABELLE, Ole BÆKGAARD NIELSEN
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